Results 121 to 130 of about 1,160,521 (256)

Rhoptry and Dense Granule Secreted Effectors Regulate CD8+ T Cell Recognition of Toxoplasma gondii Infected Host Cells

Frontiers in Immunology, 2019
Toxoplasma gondii secretes rhoptry (ROP) and dense granule (GRA) effector proteins to evade host immune clearance mediated by interferon gamma (IFN-γ), immunity-related GTPase (IRG) effectors, and CD8+ T cells.
Leah M. Rommereim, Barbara A. Fox, Kiah L. Butler, Viviana Cantillana, Gregory A. Taylor, Gregory A. Taylor, David J. Bzik   +6 more
doaj   +1 more source

Antigen presentation by supported planar membranes containing affinity-purified I-Ad. [PDF]

, 1984
Tania H. Watts, A A Brian, John W. Kappler, Philippa Marrack, Harden M. McConnell   +4 more
openalex   +1 more source

Modulation of cytomegalovirus immune evasion identifies direct antigen presentation as the predominant mode of CD8 T-cell priming during immune reconstitution after hematopoietic cell transplantation

Frontiers in Immunology
Cytomegalovirus (CMV) infection is the most critical infectious complication in recipients of hematopoietic cell transplantation (HCT) in the period between a therapeutic hematoablative treatment and the hematopoietic reconstitution of the immune system.
Rafaela Holtappels, Julia K. Büttner, Kirsten Freitag, Matthias J. Reddehase, Niels A. Lemmermann, Niels A. Lemmermann   +5 more
doaj   +1 more source

ETEC colonization factors modulate the antigen presentation function of porcine intestinal mononuclear phagocytes [PDF]

, 2013
C
Baert, Kim, Cox, Eric, Devriendt, Bert, Goddeeris, Bruno, Luo, Yu   +4 more
core   +1 more source

An Asymptotic Analysis of Bivalent Monoclonal Antibody-Antigen Binding [PDF]

arXiv
Ligand-receptor interactions are fundamental to many biological processes. For example in antibody-based immunotherapies, the dynamics of an antibody binding with its target antigen directly influence the potency and efficacy of monoclonal antibody (mAb) therapies.
arxiv  

Antigen presentation by resting B cells. Radiosensitivity of the antigen-presentation function and two distinct pathways of T cell activation. [PDF]

, 1984
Jonathan D. Ashwell, Anthony DeFranco, W E Paul, R H Schwartz   +3 more
openalex   +1 more source

The cellular redox environment alters antigen presentation

, 2014
Cysteine-containing peptides represent an important class of T cell epitopes, yet their prevalence remains underestimated. We have established and interrogated a database of around 70,000 naturally processed MHC-bound peptides and demonstrate that ...
Abdalla, Afonine, Alex Theodossis, Ambrose, Anderson, Anderson, Andrew I. Webb, Anghelina, Anthony W. Purcell, Bergmann, Bowen, Broughton, Buhl, Burnett, Butler, Butler, Campos-Perez, Castro, Chen, Collaborative Computational Project, Number 4, Craig Fett, David C. Tscharke, Davis, Davis, DeDiego, Depontieu, Dudek, Emsley, Gelderman, Ghezzi, Gong, Gonzalez-Dosal, Goulder, Griffith, Haque, Harada, Hassan, Henderson, Illing, Jamie Rossjohn, Jonathan A. Trujillo, Kim, Kittlesen, La Gruta, Lassoued, Lawless, Macdonald, Mannering, Mannering, Meadows, Merquiol, Michelle A. Dunstone, Mieyal, Mieyal, Mohammed, Murshudov, Nadine L. Dudek, Nathan P. Croft, Noah S. Butler, Otwinowski, Patricia T. Illing, Perlman, Petersen, Petersen, Petersen, Pewe, Pewe, Pierce, Purcell, Purcell, Qian, Qiao, Rudragouda Channappanavar, Saeed, Sakai, Scally, Scull, Shelton, Shilov, Stanley Perlman, Storoni, Suzuki, Tan, Theodossis, Trujillo, Trujillo-Alonso, van Venrooij, Viswanathan, Webb, Webb, Wu, Zarling, Zhao   +92 more
core   +1 more source

The antigen-processing mutant T2 suggests a role for MHC-linked genes in class II antigen presentation. [PDF]

, 1992
Janice M. Riberdy, Peter Cresswell
openalex   +3 more sources

Antigen presentation by human monocytes: evidence for stimulant processing and requirement for interleukin 1. [PDF]

, 1983
Giuseppe Scala, J J Oppenheim
openalex   +1 more source

Presenting lipid antigens

The Journal of Cell Biology, 2005
Immune cells inspect not just protein but also lipid antigens, thanks to presentation by the MHC relative CD1. Now, results from Peter van den Elzen, Michael Brenner (Harvard Medical School, Boston MA), and colleagues show that immune cells co-opt normal pathways of fat metabolism to deliver ...
openaire   +2 more sources