Results 241 to 250 of about 3,005,806 (377)

Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu, Hao Zhang, Chao Gao, Qiuhua Yu, Moli Fan, Lin‐Jie Zhang, Haipeng Zhang, Hengri Cong, Yuzhen Wei, Chotima Böttcher, Alexej Verkhratsky, Friedemann Paul, Fu‐Dong Shi, Tian Song   +13 more
wiley   +1 more source

Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery. [PDF]

J Neuroinflammation
Beretta C, Dakhel A, Eltom K, Rosqvist F, Uzoni S, Mothes T, Fletcher JS, Risérus U, Sehlin D, Rostami J, Michno WP, Erlandsson A.   +11 more
europepmc   +1 more source

Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia, Stephane Rodriguez, Emilie Dugast, Christine Lebrun‐Frenay, Eric Thouvenot, Jérôme de Sèze, Emmanuelle Le Page, Sandra Vukusic, Inès Doghri, Eric Berger, Olivier Casez, Pierre Labauge, Aurélie Ruet, Catarina Raposo, Fabienne Le Frère, Arnaud B. Nicot, Sandrine Wiertlewski, Pierre‐Antoine Gourraud, Laure Michel, Laureline Berthelot, David‐Axel Laplaud   +20 more
wiley   +1 more source

A synthetic cyclic peptide for promoting antigen presentation and immune activation. [PDF]

NPJ Vaccines
Zhang J, Madge HYR, Mahmoud A, Lu L, Wang W, Huang W, Koirala P, Gonzalez Cruz JL, Kong WY, Bashiri S, Shalash AO, Hussein WM, Khalil ZG, Wells JW, Toth I, Stephenson RJ.   +15 more
europepmc   +1 more source

Comparative Effect of Standard Versus Extended Interval Dosing of Rituximab or Ocrelizumab in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aimed to investigate the comparative effectiveness of standard versus personalized extended interval dosing of anti‐CD20 therapy on clinical and sub‐clinical outcomes in multiple sclerosis. Methods Clinical information was collected prospectively on Research Electronic Data Capture.
Nabil K. El Ayoubi, Fares Fahd, Hani Tamim, Salem Hannoun, Mark Bal, Elham El‐Hallak, Samia J. Khoury   +6 more
wiley   +1 more source

Antigen presentation of post-translationally modified peptides in major histocompatibility complexes. [PDF]

Immunol Cell Biol
de Wit AS, Bianchi F, van den Bogaart G.
europepmc   +1 more source

The Tyrosine-Containing Cytoplasmic Tail of CD1b Is Essential for Its Efficient Presentation of Bacterial Lipid Antigens [PDF]

, 1998
Robin M. Jackman, Steffen Stenger, Agnes Lee, D. Branch Moody, Rick A. Rogers, Kayvan Niazi, Masahiko Sugita, Robert L. Modlin, Peter J. Peters, Steven A. Porcelli   +9 more
openalex   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

The Oncologist, 2025, Vol, XX, Issue XX Predictive role of ARID1A and B2M mutations and the antigen presentation pathway in the efficacy of definitive chemoradiotherapy for cervical cancer. [PDF]

Oncologist
Zhu C, Gong Z, Yin P, Huang J, He D, Zhu B, Wu Y, Wang H, Zhang Y, Jing Q, Yin JC, Li Y, Liu J, Hu H, Xiao S, Sun Z, Xu H.   +16 more
europepmc   +1 more source

Processing and presentation of tetanus toxin by antigen-presenting cells from patients with chronic granulomatous disease (CGD) to human specific T cell clones are not impaired

, 1994
Catherine Barbey, J.‐M. Tiercy, Neil F. Fairweather, Heiner Niemann, Reinhard Seger, G Corradin   +5 more
openalex   +2 more sources