Results 121 to 130 of about 878,839 (299)
The MHC Class II Antigen-Processing and Presentation Pathway Is Dysregulated in Type 1 Diabetes. [PDF]
J Immunol, 2023 Gilles A +6 more
europepmc +1 more source
Vaccine strategy when the smallpox model fails: 1. immune cognition, Malaria and the Fulani [PDF]
, 2001 We begin to examine the implications of IR Cohen's work on immune cognition [1-3] for vaccine strategies when simple elicitation of sterilizing immunity fails, as is the case for HIV, tuberculosis, and malaria.
Wallace, Robert G, Wallace, Rodrick
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Corrigendum: Elucidation of the Signatures of Proteasome-Catalysed Peptide Splicing
Frontiers in Immunology, 2021 Wayne Paes +5 more
doaj +1 more source
FAK suppresses antigen processing and presentation to promote immune evasion in pancreatic cancer. [PDF]
Gut, 2023 Canel M +10 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Brazilian Journal of Medical and Biological Research, 1999 The target of any immunization is to activate and expand lymphocyte clones with the desired recognition specificity and the necessary effector functions.
Cunha-Neto E.
doaj
Clonal variation in cell surface display of an H-2 protein lacking a cytoplasmic tail [PDF]
, 1986 Truncated variants of the gene encoding H-2Ld, an integral membrane protein encoded by the major histocompatibility complex, were constructed by in vitro mutagenesis to elucidate the function of charged amino acids found on the cytoplasmic side of the ...
Hood, Leroy E., Zuñiga, Martha C.
core