Results 101 to 110 of about 4,134,311 (295)

Schematic of antigen processing and presentation pathway for Hsp70 and Hsp90 generated by DAVID.

open access: yes, 2012
DAVID utilized the KEGG pathways to diagram the role of Hsp70 and Hsp90 for antigen processing and presentation. Both Hsp70 and Hsp90 (red stars) are involved in MHC class I antigen processing.
Paul Grieco (135487)   +6 more
core   +1 more source

Differential Antigen Processing by Dendritic Cell Subsets in Vivo [PDF]

open access: yes, 2007
Dendritic cells (DCs) process and present self and foreign antigens to induce tolerance or immunity. In vitro models suggest that induction of immunity is controlled by regulating the presentation of antigen, but little is known about how DCs control ...
박채규
core   +1 more source

Antigen processing for amateurs and professionals

open access: yesTrends in Cell Biology, 1998
The initiation and propagation of immune responses is dependent on the ability of antigen-presenting cells (APCs) to convert proteins into peptides, to load them intracellularly onto major histocompatibility complex (MHC) products and then to deliver the peptide-MHC complexes to the plasma membrane.
I, Mellman, S J, Turley, R M, Steinman
openaire   +2 more sources

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

Overview of the 3 steps of antigen processing that are modeled using the current approach.

open access: yes, 2018
Overview of the 3 steps of antigen processing that are modeled using the current approach.
Dina Schneidman-Duhovny (10167)   +10 more
core   +1 more source

Cellular stress increases DRIP production and MHC Class I antigen presentation

open access: yesFrontiers in Immunology
BackgroundDefective ribosomal products (DRiPs) are non-functional proteins rapidly degraded during or after translation being an essential source for MHC class I ligands.
Natalie Pach   +2 more
doaj   +1 more source

An Unexpected Major Role for Proteasome-Catalyzed Peptide Splicing in Generation of T Cell Epitopes: Is There Relevance for Vaccine Development?

open access: yesFrontiers in Immunology, 2017
Efficient and safe induction of CD8+ T cell responses is a desired characteristic of vaccines against intracellular pathogens. To achieve this, a new generation of safe vaccines is being developed accommodating single, dominant antigens of pathogens of ...
Anouk C. M. Platteel   +6 more
doaj   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

open access: yesMolecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani   +7 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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