Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source
Interferons and Resistance Mechanisms in Tumors and Pathogen-Driven Diseases-Focus on the Major Histocompatibility Complex (MHC) Antigen Processing Pathway. [PDF]
Massa C, Wang Y, Marr N, Seliger B.
europepmc +1 more source
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao +5 more
wiley +1 more source
Editorial: Insights in antigen presenting cell biology: 2022
Peter van Endert, Peter van Endert
doaj +1 more source
Modulating antigen processing through metal-organic frameworks to bias adaptive immunity. [PDF]
Cho E +8 more
europepmc +1 more source
The circadian clock influences T cell responses to vaccination by regulating dendritic cell antigen processing. [PDF]
Cervantes-Silva MP +21 more
europepmc +1 more source
Antigen Processing and Presentation [PDF]
openaire +2 more sources
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos +9 more
wiley +1 more source
Viral manipulation of the HLA class I antigen processing and presentation pathway. [PDF]
Nolan DS, Altenburg AF.
europepmc +1 more source
An antigen processing and presentation signature for prognostic evaluation and immunotherapy selection in advanced gastric cancer. [PDF]
Wang KW +8 more
europepmc +1 more source

