Results 161 to 170 of about 4,134,311 (295)

Pan-cancer analysis identifies immunoproteasome as the predominant survival-associated component of antigen processing machinery. [PDF]

Transl Oncol
Lai JI, Liu CY, Tsai YF, Huang CC, Tseng LM, Chao TC.   +5 more
europepmc   +1 more source

SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8⁺ T cell responses. [PDF]

Heliyon, 2023
Wellington D, Yin Z, Yu Z, Heilig R, Davis S, Fischer R, Felce SL, Antoun E, Hublitz P, Beveridge R, Dong D, Liu G, Yao X, Peng Y, Kessler BM, Dong T.   +15 more
europepmc   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

Transglutaminase 2 at the Interface of Gene Regulation and Antigen Processing in HLA-Restricted Immunity of Celiac Disease. [PDF]

Genes (Basel)
Cannea FB, Padiglia A.
europepmc   +1 more source

Alanine-based spacers promote an efficient antigen processing and presentation in neoantigen polypeptide vaccines. [PDF]

Cancer Immunol Immunother, 2023
Aguilar-Gurrieri C, Barajas A, Rovirosa C, Ortiz R, Urrea V, de la Iglesia N, Clotet B, Blanco J, Carrillo J.   +8 more
europepmc   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Modulating antigen processing through metal-organic frameworks to bias adaptive immunity. [PDF]

Proc Natl Acad Sci U S A
Cho E, Davis MA, Nowak JA, Izzo M, Ferrante AM, Sha F, Magdalenski JS, Farha OK, Teplensky MH.   +8 more
europepmc   +1 more source

A cell-free antigen processing system informs HIV-1 epitope selection and vaccine design. [PDF]

J Exp Med, 2023
Sengupta S, Zhang J, Reed MC, Yu J, Kim A, Boronina TN, Board NL, Wrabl JO, Shenderov K, Welsh RA, Yang W, Timmons AE, Hoh R, Cole RN, Deeks SG, Siliciano JD, Siliciano RF, Sadegh-Nasseri S.   +17 more
europepmc   +1 more source

“Activation‐Resistance Elimination” Regulation by Lanthanide/Transition Metal Ion‐Coordinated Nanostructures Intensifies Cuproptosis and Tumor Immunotherapy

Advanced Materials, EarlyView.
The lanthanide/transition metal ion coordination nanoparticles, La‐Cu@Lap/IWR‐1, with optimized coordination, have been proven to achieve remarkable results in realizing comprehensive tumor cuproptosis through efficient cuproptosis activation and multidimensional resistance elimination, thereby synchronously realizing the synergistic antitumor effects ...
Junrong Wang, Mengqian Xu, Huaping Zhao, Yulin Xie, Guoqing Zhu, Haoze Li, Qianqian Sun, Yong Lei, Chunxia Li   +8 more
wiley   +1 more source

Viral manipulation of the HLA class I antigen processing and presentation pathway. [PDF]

Front Immunol
Nolan DS, Altenburg AF.
europepmc   +1 more source