Results 111 to 120 of about 2,182,609 (246)
Antigenic Variation in Viruses
, 2016 Persistent virus Infections represent an immunologlcal paradox, in that viruses persist in the face of normal immune responses. The classical serological studies on viruses causing acute Infections established a remarkable degree of antigen and ...
Birrer, Michael J, Bloom, Barry R
core +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Understanding chromatin dynamics during antigenic variation in trypanosoma brucei [PDF]
, 2016 Tese de doutoramento, Ciências Biomédicas (Microbiologia e Parasitologia), Universidade de Lisboa, Faculdade de Medicina, 2016African trypanosomiasis is a disease restricted to sub-Saharian Africa and it assumes two forms: Human African trypanosomiasis ...
Branco, Francisco Maria dos Santos e Silva Aresta, 1985-
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Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
R-loops modulate Trypanosome antigenic variation.
PLoS Genetics, 2018 Lauren L Prister, H Steven Seifert
doaj +1 more source
Emerging Microbes and InfectionsSeasonal influenza A/H3N2 poses a significant public health burden due to its rapid antigenic evolution, necessitating frequent vaccine updates. This study systematically analysed the antigenic evolution of 14 H3N2 vaccine strains (2000–2022) using ...
Yimeng An +7 more
doaj +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Antigenic variation among circulating H5N1 highly pathogenic avian influenza A viruses mandates the continuous production of strain-specific pre-pandemic vaccine candidates and represents a significant challenge for pandemic preparedness.
core
Antigenic variation of the bovine ephemeral fever virus glycoprotein. [PDF]
, 1992 Antigenic variation in the bovine ephemeral fever virus glycoprotein was demonstrated using monoclonal antibodies and comparing a particular passage level of the BB7721 strain with (1) other Australian isolates of BEF virus, (2) the Beijing 1 strain of ...
T D St, George, D H Cybinski
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Publisher Correction: Fungal antigenic variation using mosaicism and reassortment of subtelomeric genes' repertoires. [PDF]
Nat Commun, 2023 Meier CS +8 more
europepmc +1 more source