Results 11 to 20 of about 184,601 (247)
Identification of Circulating Bacterial Antigens by
mBio, 2011 Detection of microbial antigens in clinical samples can lead to rapid diagnosis of an infection and administration of appropriate therapeutics. A major barrier in diagnostics development is determining which of the potentially hundreds or thousands of ...
Dana E. Nuti +13 more
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Antigenic Variation in Bacterial Pathogens [PDF]
Microbiology Spectrum, 2016 ABSTRACT Antigenic variation is a strategy used by a broad diversity of microbial pathogens to persist within the mammalian host. Whereas viruses make use of a minimal proofreading capacity combined with large amounts of progeny to use random mutation for variant generation, antigenically variant bacteria have evolved mechanisms ...
Palmer, Guy H +2 more
openaire +4 more sources
Outer membrane vesicles: A bacterial-derived vaccination system
Frontiers in Microbiology, 2022 Outer membrane vesicles (OMVs) are non-living spherical nanostructures that derive from the cell envelope of Gram-negative bacteria. OMVs are important in bacterial pathogenesis, cell-to-cell communication, horizontal gene transfer, quorum sensing, and ...
Linda A. Lieberman
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Emerging Microbes and Infections, 2020 Burkholderia cenocepacia is an emerging opportunistic pathogen for people with cystic fibrosis and chronic granulomatous disease. Intracellular survival in macrophages within a membrane-bound vacuole (BcCV) that delays acidification and maturation into ...
Roberto Rosales-Reyes +10 more
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Frontiers in Immunology, 2022 Acinetobacter baumannii is a human bacterial pathogen of increasing concern in clinical settings due to the emergence of antibiotic resistant strains and the lack of effective therapeutics.
Somshukla Chaudhuri +6 more
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Synthetic carbohydrate-based vaccines: challenges and opportunities
Journal of Biomedical Science, 2020 Glycoconjugate vaccines based on bacterial capsular polysaccharides (CPS) have been extremely successful in preventing bacterial infections. The glycan antigens for the preparation of CPS based glycoconjugate vaccines are mainly obtained from bacterial ...
Ravinder Mettu +2 more
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The uptake of soluble and particulate antigens by epithelial cells in the mouse small intestine. [PDF]
PLoS ONE, 2014 Intestinal epithelial cells (IECs) overlying the villi play a prominent role in absorption of digested nutrients and establish a barrier that separates the internal milieu from potentially harmful microbial antigens.
Savannah E Howe +4 more
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Nature Communications, 2020 The O-antigen of LPS is known to limit the binding of antibody to bacterial surface antigens. Here the AUs show that the chemical and physical structure of the O-antigen are central factors in limiting the exposure of surface antigens to antibodies ...
C. Coral Domínguez-Medina +23 more
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Bacterial Spore Antigens: a Review [PDF]
Journal of General Microbiology, 1962 SUMMARY: Agglutinogens and precipitinogens have been detected in the spores of many species of aerobic and anaerobic spore-formers and these antigens are distinct from those of the vegetative growth phases of the corresponding organisms. Spore antigens are heat resistant and antibody response is elicited by the injection of autoclaved spores into ...
openaire +3 more sources
What are the likely causes of breast implant associated anaplastic large cell lymphoma (BIA-ALCL)?
JPRAS Open, 2022 Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a CD30-positive, anaplastic lymphoma kinase-negative T-cell lymphoma. Where implant history is known, all confirmed cases to date have occurred in patients with exposure to textured ...
Sepehr S. Lajevardi +3 more
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