Results 11 to 20 of about 320,891 (294)
Human colon stem cells are the predominant epithelial responders to bacterial antigens [PDF]
Frontiers in ImmunologyIntestinal epithelial cells (IECs) are capable of mounting an adequate antimicrobial inflammatory response to pathogens while tolerating commensals. The underlying regulatory mechanisms of immune sensitivity remain incompletely understood, particularly ...
Maaike H. De Vries +24 more
doaj +2 more sources
Phenotypic and genotypic characterization of locally isolated Salmonella strains used in preparation of Salmonella antigens in Egypt [PDF]
Veterinary World, 2016 Aim: This work was conducted to study the phenotypic and genotypic characterization of locally isolated Salmonella strains (Salmonella Pullorum, Salmonella Enteritidis, and Salmonella Typhimurium) from poultry used in the preparation of Salmonella ...
Hazem Mohammed Ibrahim +3 more
doaj +1 more source
Glycosylation of bacterial antigens changes epitope patterns
Frontiers in Immunology, 2023 IntroductionUnlike glycosylation of proteins expressed in mammalian systems, bacterial glycosylation is often neglected in the development of recombinant vaccines.MethodsHere, we compared the effects of glycosylation of YghJ, an Escherichia coli protein ...
Karolin Kern +17 more
doaj +1 more source
Polysaccharide Vaccines: A Perspective on Non-Typhoidal Salmonella
Polysaccharides, 2021 Polysaccharides are often the most abundant antigens found on the extracellular surfaces of bacterial cells. These polysaccharides play key roles in interactions with the outside world, and for many bacterial pathogens, they represent what is presented ...
Sumudu R. Perera +2 more
doaj +1 more source
Comprehensive antigen screening identifies Moraxella catarrhalis proteins that induce protection in a mouse pulmonary clearance model. [PDF]
PLoS ONE, 2013 Moraxella catarrhalis is one of the three most common causative bacterial pathogens of otitis media, however no effective vaccine against M. catarrhalis has been developed so far. To identify M.
Margarita Smidt +13 more
doaj +1 more source
MicroRNA-762 is upregulated in human corneal epithelial cells in response to tear fluid and Pseudomonas aeruginosa antigens and negatively regulates the expression of host defense genes encoding RNase7 and ST2. [PDF]
, 2013 Mucosal surfaces regulate defenses against infection and excessive inflammation. We previously showed that human tears upregulated epithelial expression of genes encoding RNase7 and ST2, which inhibited Pseudomonas aeruginosa invasion of human corneal ...
Chan, Gary +5 more
core +5 more sources
Vaccines, 2020 This study was designed to evaluate the immunogenicity and protective efficacy of two VP1 chimeric antigens of bacterial ghosts. Inoculation of the two VP1 chimeric antigens of bacterial ghosts into BALB/c mice markedly elicited humoral and mucosal ...
Saisai Gong +11 more
doaj +1 more source
Diagnostics, 2021 Massive worldwide serological testing for SARS-CoV-2 is needed to determine the extent of virus exposure in a particular region, the ratio of symptomatic to asymptomatic infected persons, and the duration and extent of immunity after infection.
Alan Roberto Márquez-Ipiña +10 more
doaj +1 more source
Antigenic Variation in Bacterial Pathogens [PDF]
Microbiology Spectrum, 2016 ABSTRACT Antigenic variation is a strategy used by a broad diversity of microbial pathogens to persist within the mammalian host. Whereas viruses make use of a minimal proofreading capacity combined with large amounts of progeny to use random mutation for variant generation, antigenically variant bacteria have evolved mechanisms ...
Palmer, Guy H +2 more
openaire +3 more sources
Frontiers in Immunology, 2021 Antibody therapy may be an alternative treatment option for infections caused by the multi-drug resistant (MDR) bacterium Acinetobacter baumannii. As A.
Gathoni Kamuyu +10 more
doaj +1 more source