Results 201 to 210 of about 2,347,137 (336)

Flavonifractor Plautii or Its Metabolite Desaminotyrosine as Prophylactic Agents for Alleviating Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
The gut microbiome is a potential target for treating cardiovascular disease. It is found that prophylactic administration of Flavonifractor plautii or its metabolite desaminotyrosine (DAT) exerts pleiotropic cardioprotective effects via promoting cardiomyocyte survival and attenuating cardiac inflammation against myocardial ischemia/reperfusion (I/R ...
Heng Du, Xu Liu, Jianghua Shen, Hailong Yuan, Hao Zhang, Gan Xi, Yujing Li, Yuhan Wang, Jiahe Zhang, Chaofan Yang, Pengfei Xu, Jiawan Wang, Fang Wang, Siqi Liu, Yanan Zhou, Qi Gu, Jingjing Lu, Tuo Wei, Zeyu Gao, Jingyi Zang, Jun Wang, Moshi Song   +21 more
wiley   +1 more source

Development of a set of bacterial engineered glycoconjugates as novel serogroup-specific antigens for the serodiagnosis of Escherichia coli O26, O111, O103 and O45 infections associated to hemolytic uremic syndrome. [PDF]

Microb Cell Fact
Caillava AJ, Melli LJ, Landoni M, Landivar SM, Chinen I, Couto AS, Rivas M, Ugalde JE, Comerci DJ, Ciocchini AE.   +9 more
europepmc   +1 more source

Engineered Genetic Circuits Activated by Bezafibrate Improve ESC‐Based TAA Cancer Vaccine Efficacy and PD‐L1 Nanobody Therapy

Advanced Science, EarlyView.
Synthetic gene circuits regulated by bezafibrate are developed to express tumor antigens and PD‐L1 nanobody (PD‐L1nb), enhancing cancer immunotherapy. Delivered via HEK293T cells, ESCs, or directly injected the plasmids containing the circuit into the tumor, the circuits reduce tumor growth, boost CD8+ T cells, and minimize T cell exhaustion.
Meiling Jin, Shuzhen Liu, Mingshuo Zhan, Jian‐Dong Huang   +3 more
wiley   +1 more source

Rapid detection of Ornithobacterium rhinotracheale infection by a latex agglutination test in turkeys. [PDF]

Poult Sci
Yousefinejad S, Khosravi M, Gharibi D, Mayahi M, Shapouri MRSA.   +4 more
europepmc   +1 more source

STUDIES ON THE ANTIGENIC PATTERNS OF BACTERIAL FLAGELLA

Japanese Journal of Medical Science and Biology, 1952
Rintaro Nakaya, Hideo Fukumi, Hisao Uchida   +2 more
openaire   +3 more sources

T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease

Nature Structural & Molecular Biology, 2019
J. Petersen, Laura Ciacchi, Mai T. Tran, K. L. Loh, Y. Kooy-Winkelaar, N. Croft, M. Hardy, Zhenjun Chen, J. McCluskey, R. Anderson, A. Purcell, J. Tye-Din, F. Koning, H. Reid, J. Rossjohn   +14 more
semanticscholar   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

Advanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua, Limin Kong, Li Fan, Yanan Bai, Yujun Zhou, Yanfang Zhang, Qingwei Zhao, Xiaoyang Lu, Hongyu Yang, Hangyang Li, Peili Ding, Yuyu Nan, Qinghua Ji, Ping Yang, Lu Li, Yijing Xin, Lijuan Zhao, Wei Yang, Wenqiao Yu, Saiping Jiang   +19 more
wiley   +1 more source

rLVS Δ<i>capB</i>/Yp F1-V single vector platform vaccine expressing <i>Yersinia pestis</i> F1 and LcrV antigens provides complete protection against lethal respiratory challenge with virulent plague bacilli. [PDF]

Hum Vaccin Immunother
Jia Q, Bowen RA, Masleša-Galić S, Horwitz MA.   +3 more
europepmc   +1 more source

Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague

Advanced Science, EarlyView.
The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia, Yinon Levy, Hila Cohen, Ayelet Zauberman, David Gur, Inbal Hazan‐Halevy, Moshe Aftalion, Shani Benarroch, Erez Bar‐Haim, Orit Redy‐Keisar, Ofer Cohen, Dan Peer, Emanuelle Mamroud   +12 more
wiley   +1 more source

<i>Shigella</i> Mutant with Truncated O-Antigen as an Enteric Multi-Pathogen Vaccine Platform. [PDF]

Vaccines (Basel)
Kim JO, Nothaft H, Moon Y, Jeong S, Vortherms AR, Song M, Szymanski CM, White J, Walker R.   +8 more
europepmc   +1 more source