Results 21 to 30 of about 320,891 (294)

Systematic Chemoenzymatic Synthesis of O-Sulfated Sialyl Lewis x Antigens. [PDF]

, 2015
O-Sulfated sialyl Lewis x antigens play important roles in nature. However, due to their structural complexity, they are not readily accessible by either chemical or enzymatic synthetic processes.
Chen, Xi, Kenyond, Nicholas J, Li, Yanhong, Louie, Angelique Y, Muthana, Musleh M, Santra, Abhishek, Tasnima, Nova, Yu, Hai, Zeng, Jie   +8 more
core   +1 more source

Epidemiologic Survey of Legionella Urine Antigen Testing Within a Large Wisconsin-Based Health Care System

Journal of Patient-Centered Research and Reviews, 2020
Purpose: Legionella pneumophila pneumonia is a life-threatening, environmentally acquired infection identifiable via Legionella urine antigen tests (LUAT).
Caroline P. Toberna, Hannah M. William, Jessica J. F. Kram, Kayla Heslin, Dennis J. Baumgardner   +4 more
doaj   +1 more source

Identification of Circulating Bacterial Antigens by In Vivo Microbial Antigen Discovery

mBio, 2011
Detection of microbial antigens in clinical samples can lead to rapid diagnosis of an infection and administration of appropriate therapeutics. A major barrier in diagnostics development is determining which of the potentially hundreds or thousands of ...
Dana E. Nuti, Reva B. Crump, Farida Dwi Handayani, Narisara Chantratita, Sharon J. Peacock, Richard Bowen, Philip L. Felgner, D. Huw Davies, Terry Wu, C. Rick Lyons, Paul J. Brett, Mary N. Burtnick, Thomas R. Kozel, David P. AuCoin   +13 more
doaj   +1 more source

Proteomics-identified Bvg-activated autotransporters protect against bordetella pertussis in a mouse model. [PDF]

PLoS ONE, 2014
Pertussis is a highly infectious respiratory disease of humans caused by the bacterium Bordetella pertussis. Despite high vaccination coverage, pertussis has re-emerged globally.
Daan de Gouw, Marien I de Jonge, Peter W M Hermans, Hans J C T Wessels, Aldert Zomer, Alinda Berends, Catherine Pratt, Guy A Berbers, Frits R Mooi, Dimitri A Diavatopoulos   +9 more
doaj   +1 more source

Outer membrane vesicles: A bacterial-derived vaccination system

Frontiers in Microbiology, 2022
Outer membrane vesicles (OMVs) are non-living spherical nanostructures that derive from the cell envelope of Gram-negative bacteria. OMVs are important in bacterial pathogenesis, cell-to-cell communication, horizontal gene transfer, quorum sensing, and ...
Linda A. Lieberman
doaj   +1 more source

Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]

, 2015
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam, Kerber, Sarah, Pluschke, Gerd, Zimmer, Gert   +3 more
core   +3 more sources

Lipopolysaccharide-specific acyloxyacyl hydrolase [PDF]

, 1991
" An acyloxyacyl hydrolase from the human promyelocyte cell line HL-60 has been found to specifically hydrolyze fatty acids from their ester linkages to hydroxy groups of 3-hydroxyfatty acids, the latter being being bound in turn to lipopolysaccharide ...
Hall, Catherine L., Munford, Robert S.
core   +1 more source

Interferon-gamma-activated macrophages infected with Burkholderia cenocepacia process and present bacterial antigens to T-cells by class I and II major histocompatibility complex molecules

Emerging Microbes and Infections, 2020
Burkholderia cenocepacia is an emerging opportunistic pathogen for people with cystic fibrosis and chronic granulomatous disease. Intracellular survival in macrophages within a membrane-bound vacuole (BcCV) that delays acidification and maturation into ...
Roberto Rosales-Reyes, Paola Garza-Villafuerte, Daniela Vences-Vences, Daniel F. Aubert, Rubi Aca-Teutle, Vianney F. Ortiz-Navarrete, Laura C. Bonifaz, Julio Cesar Carrero-Sánchez, Alfonso Olivos-García, Miguel A. Valvano, José Ignacio Santos-Preciado   +10 more
doaj   +1 more source

Deficiency of RgpG causes major defects in cell division and biofilm formation, and deficiency of LytR-CpsAPsr family proteins leads to accumulation of cell wall antigens in culture medium by Streptococcus mutans [PDF]

, 2017
Streptococcus mutans is known to possess rhamnose-glucose polysaccharide (RGP), a major cell wall antigen. S. mutans strains deficient in rgpG , encoding the first enzyme of the RGP biosynthesis
Beatty, Wandy L, Bitoun, Jacob P, De, Arpan, Liao, Sumei, Roth, Randy, Wen, Zezhang T, Wu, Hui   +6 more
core   +2 more sources

Hybrid antigens expressing surface loops of BauA from Acinetobacter baumannii are capable of inducing protection against infection

Frontiers in Immunology, 2022
Acinetobacter baumannii is a human bacterial pathogen of increasing concern in clinical settings due to the emergence of antibiotic resistant strains and the lack of effective therapeutics.
Somshukla Chaudhuri, Iraj Rasooli, Ramin Hatefi Oskouei, Mahdi Pishgahi, Abolfazl Jahangir, Vahid Farshchi Andisi, Anthony B. Schryvers   +6 more
doaj   +1 more source