Results 41 to 50 of about 184,601 (247)

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

EFFECTIVENESS OF A TEST-SVSTEM FOR DIAGNOSTICS OF MELIOIDOSIS AND GLANDERS BASED ON PASSIVE HEMAGGLUTINATION REACTION AND SOLID-PHASE ENZYME IMMUNOASSAY

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Analysis of published results of studies of effect of various antigens of Burkholderia pseudomallei and B. mallei on operation characteristics (sensitivity and specificity) of tests for diagnostics of melioidosis and glanders based on reaction of passive
A. A. Budchenko
doaj   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Assessment of clinical state of the palatine tonsils of patients with chronic tonsillitis after immynotherapy in the form of vaccination with bacterial antigens

Acta Medica Leopoliensia, 2018
Aim. Determine the effect of mucosal vaccination on changes in the clinical status of patients with chronic tonsillitis. Materials and Metods. In these clinical studies, 92 patients aged 18 to 40 years participated.
O.I. Tynitovska
doaj   +1 more source

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

House dust mites as potential carriers for IgE sensitization to bacterial antigens

Revista Alergia México, 2018
Background: IgE-reactivity to antigens from gram-positive and negative bacteria is common in patients suffering from respiratory and skin manifestations of allergy, but the routes and mechanisms of sensitisation are not fully understood.
Sheron Dzoro, Irene Mittermann, Yvonne Resch, Susanne Vrtala, Marion Nehr, Alexander M. Hirschl, Gustav Wikberg, Lena Lundeberg, Catharina Johansson, Annika Scheynius, Rudolf Valenta   +10 more
doaj  

Salmonella modulates B cell biology to evade CD8+ T cell-mediated immune responses

Frontiers in Immunology, 2014
Although B cells and antibodies are the central effectors of humoral immunity, B cells can also produce and secrete cytokines and present antigen to helper T cells.
Marcela eLopez-Medina, Araceli ePerez-Lopez, Araceli ePerez-Lopez, Celia eAlpuche-Aranda, Vianney eOrtiz-Navarrete   +4 more
doaj   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

FEATURES OF IMMUNE RESPONSE DURING VARIOUS SCHEMES OF USE OF BACTERIAL THERAPEUTIC VACCINE IMMUNOVAC VP-4

Журнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. Study the dynamics of immunologic parameters in patients with chronic bacterial infections during various schemes of administration of Immunovac VP-4 vaccine. Materials and methods.
L. I. Krasnoproshina, T. A. Serova, E. P. Foshina, I. V. Bisheva, S. A. Skhodova   +4 more
doaj   +1 more source

Outer membrane vesicles (OMVs) and their therapeutic potential as anti-infectious agents

Nano Trends
Outer membrane vesicles (OMVs) derived from Gram-negative bacteria have emerged as promising therapeutic agents for combating infectious diseases. These small, spherical structures carry diverse cargo molecules, including virulence factors, antigens, and
Mariana Ottaiano Gonçalves, Paula Maria Pincela Lins, Giulia Kassab, Vanderlei Bagnato, Valtencir Zucolotto   +4 more
doaj   +1 more source