This study focuses on developing accurate immunoassays for diagnosing Chagas disease (CD), a challenging task due to antigenic similarities between Trypanosoma cruzi and other parasites, leading to cross-reactivity.
Emily F. Santos +13 more
doaj +1 more source
Study of Autoantibodies and DQ Antigens in Patient with Celiac Disease [PDF]
Introduction: Celiac Disease (CD) is a chronic autoimmune mediated disorder triggered by the ingestion of gluten. It is seen in genetically predisposed person and results in small intestine injury. Its aetiopathogenesis is not clear.
Andleeb Zehra +7 more
doaj +1 more source
Comparison of schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections [PDF]
A Schistosoma mansoni cercarial antigen preparation (cercarial transformation fluid – SmCTF) was evaluated for detection of anti-schistosome antibodies in human sera in 4 collaborating laboratories.
Dawson, E. +40 more
core +1 more source
Induction of Immune Tolerance to Dietary Antigens [PDF]
The intestinal immune system is continuously exposed to massive amounts of diverse antigens derived from both food and intestinal microbes. Immunological tolerance to these enteric antigens is critical for ensuring intestinal and systemic immune ...
Kwang Soon Kim +3 more
core +1 more source
Accuracy of chimeric proteins in the serological diagnosis of chronic chagas disease - a Phase II study. [PDF]
BACKGROUND:The performance of current serologic tests for diagnosing chronic Chagas disease (CD) is highly variable. The search for new diagnostic markers has been a constant challenge for improving accuracy and reducing the number of inconclusive ...
Fred Luciano Neves Santos +7 more
doaj +1 more source
Identification of protective antigens for vaccination against systemic salmonellosis [PDF]
There is an urgent medical need for improved vaccines with broad serovar coverage and high efficacy against systemic salmonellosis. Subunit vaccines offer excellent safety profiles but require identification of protective antigens, which remains a ...
Dirk eBumann, Bumann, Dirk, Dirk Bumann
core +1 more source
Serum anti-glycan-antibodies in relatives of patients with inflammatory bowel disease. [PDF]
Serum anti-glycan antibodies are a promising tool for differential diagnosis, disease stratification and prediction of Crohn's disease (CD). To investigate possible heritability of the markers we assessed the presence of serum anti-glycan antibodies in ...
Florian Kamm +8 more
doaj +1 more source
The role and mechanism of erythroid precursor cells in Alzheimer's disease
Objective To investigate the role and mechanism of erythroid precursor cells (EPC) and its subtypes in Alzheimer's disease (AD). Methods The patients with AD (AD group) firstly diagnosed and treated in Qinghai Provincial People's Hospital from October ...
LI Na +3 more
doaj +1 more source
Identification and characterization of peripheral T-cell lymphoma-associated SEREX antigens. [PDF]
Peripheral T-cell lymphomas (PTCL) are generally less common and pursue a more aggressive clinical course than B-cell lymphomas, with the T-cell phenotype itself being a poor prognostic factor in adult non-Hodgkin lymphoma (NHL).
Graham P. Collins +34 more
core +2 more sources
Human neutrophil clearance of bacterial pathogens triggers anti-microbial gamma delta T cell responses in early infection [PDF]
Human blood Vc9/Vd2 T cells, monocytes and neutrophils share a responsiveness toward inflammatory chemokines and are rapidly recruited to sites of infection.
Davey Martin S. +93 more
core +2 more sources

