Results 41 to 50 of about 830,599 (290)

Serodiagnosis of Echinococcus spp. infection: explorative selection of diagnostic antigens by peptide microarray [PDF]

, 2010
BACKGROUND: Production of native antigens for serodiagnosis of helminthic infections is laborious and hampered by batch-to-batch variation. For serodiagnosis of echinococcosis, especially cystic disease, most screening tests rely on crude or purified ...
Maag, Eva, List, C, List, C., Gottstein, Bruno, Gottstein Bruno, Felger Ingrid, Felger, Ingrid, Qi, W, Gottstein, B., Ingrid Felger, Maag Eva, Qi Weihong, Müller, N., Felger, I, Müller, Norbert, Norbert Müller, List, Claudia, Gottstein, B, Müller Norbert, Felger, I., Maag, E., Müller, N, Qi, W., Eva Maag, Bruno Gottstein, List Claudia, Claudia List, Maag, E, Qi, Weihong, Weihong Qi   +29 more
core   +2 more sources

Stability Assessment of Four Chimeric Proteins for Human Chagas Disease Immunodiagnosis

Biosensors, 2021
The performance of an immunoassay relies on antigen-antibody interaction; hence, antigen chemical stability and structural integrity are paramount for an efficient assay.
Paola Alejandra Fiorani Celedon, Leonardo Maia Leony, Ueriton Dias Oliveira, Natália Erdens Maron Freitas, Ângelo Antônio Oliveira Silva, Ramona Tavares Daltro, Emily Ferreira Santos, Marco Aurélio Krieger, Nilson Ivo Tonin Zanchin, Fred Luciano Neves Santos   +9 more
doaj   +1 more source

Monoclonal antibodies against rat leukocyte surface antigens.

, 2001
Monoclonal antibodies have proven to be powerful tools for studying the properties of leukocyte surface antigens and the cells that express them. In the past decades many monoclonal antibodies (mAb) for identifying the different rat leukocyte surface ...
van den Berg, TK, Dijkstra, CD, Puklavec, MJ, Barclay, Neil   +3 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Human antibodies against Mycobacterium avium ssp. paratuberculosis combined with cytokine levels for the diagnosis and selection of Crohn's disease patients for anti-mycobacterial therapy-A pilot study.

PLoS ONE
Increasing evidence links a worldwide bacterial infection of cattle and other animal species by Mycobacterium avium ssp. paratuberculosis (MAP) to Crohn's disease (CD).
J Todd Kuenstner, Peilin Zhang, Raghava Potula, Jean-Michel Galarneau, Horacio Bach   +4 more
doaj   +1 more source

The Morphology and Phenotype of Monocyte-Macrophages When Cultured on Bionanofilms Substrates with Different Surface Relief Profiles

Biomolecules, 2019
The effect of surface relief profiles of alkanoate-based bionanofilms to the monocyte-macrophages (MN-MPhs) from peripheral blood of patients with atherosclerosis was studied in vitro. Patients were subjected to coronary stenting.
Natalia G. Menzyanova, Svetlana A. Pyatina, Alexander V. Shabanov, Ivan V. Nemtsev, Dmitry P. Stolyarov, Dmitry B. Dryganov, Eugene V. Sakhnov, Ekaterina I. Shishatskaya   +7 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A Characterization of the Humoral Immune Response to Human Endogenous Retroviruses and Mycobacterium paratuberculosis in Crohn’s Disease

Pathogens
Crohn’s disease (CD) is a multifactorial polygenic inflammatory bowel disease linked to aberrant immune response. Mycobacterium paratuberculosis (MAP) has been associated with CD; however, detecting MAP in CD tissues remains highly challenging. Recently,
Alishba Fayyaz, Luigi Cugia, Marta Noli, Somaye Jasemi, Elena Rita Simula, Leonardo A. Sechi   +5 more
doaj   +1 more source

Loss and Gain of Tolerance to Pancreatic Glycoprotein 2 in Celiac Disease.

PLoS ONE, 2015
BackgroundAutoantibodies against pancreatic secretory-granule membrane glycoprotein 2 (GP2) have been demonstrated in patients with Crohn's disease but recently also with celiac disease (CD).
Martin W Laass, Nadja Röber, Ursula Range, Lydia Noß, Dirk Roggenbuck, Karsten Conrad   +5 more
doaj   +1 more source

CD Antigens 2001: Aims and Results of HLDA Workshops [PDF]

Stem Cells, 2001
aThe Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Oxford, United Kingdom; bCentre d'Immunologie, Parc Scientifique de Luminy, Cedex, France; cFaculte de Medicine de Creteil, Cedex, France; dDivision of Immunity and Infection, MRC Center for Immune Regulation, Department of Rheumatology, University of Birmingham, Edgbaston,
D, Mason, P, André, A, Bensussan, C, Buckley, C, Civin, E, Clark, M, de Haas, S, Goyert, M, Hadam, D, Hart, V, Horejsí, S, Meuer, J, Morrissey, R, Schwartz-Albiez, S, Shaw, D, Simmons, M, Uguccioni, E, van der Schoot, E, Vivier, H, Zola   +19 more
openaire   +2 more sources