Results 31 to 40 of about 74,124 (163)

Stability Assessment of Four Chimeric Proteins for Human Chagas Disease Immunodiagnosis

Biosensors, 2021
The performance of an immunoassay relies on antigen-antibody interaction; hence, antigen chemical stability and structural integrity are paramount for an efficient assay.
Paola Alejandra Fiorani Celedon, Leonardo Maia Leony, Ueriton Dias Oliveira, Natália Erdens Maron Freitas, Ângelo Antônio Oliveira Silva, Ramona Tavares Daltro, Emily Ferreira Santos, Marco Aurélio Krieger, Nilson Ivo Tonin Zanchin, Fred Luciano Neves Santos   +9 more
doaj   +1 more source

The Morphology and Phenotype of Monocyte-Macrophages When Cultured on Bionanofilms Substrates with Different Surface Relief Profiles

Biomolecules, 2019
The effect of surface relief profiles of alkanoate-based bionanofilms to the monocyte-macrophages (MN-MPhs) from peripheral blood of patients with atherosclerosis was studied in vitro. Patients were subjected to coronary stenting.
Natalia G. Menzyanova, Svetlana A. Pyatina, Alexander V. Shabanov, Ivan V. Nemtsev, Dmitry P. Stolyarov, Dmitry B. Dryganov, Eugene V. Sakhnov, Ekaterina I. Shishatskaya   +7 more
doaj   +1 more source

A Characterization of the Humoral Immune Response to Human Endogenous Retroviruses and Mycobacterium paratuberculosis in Crohn’s Disease

Pathogens
Crohn’s disease (CD) is a multifactorial polygenic inflammatory bowel disease linked to aberrant immune response. Mycobacterium paratuberculosis (MAP) has been associated with CD; however, detecting MAP in CD tissues remains highly challenging. Recently,
Alishba Fayyaz, Luigi Cugia, Marta Noli, Somaye Jasemi, Elena Rita Simula, Leonardo A. Sechi   +5 more
doaj   +1 more source

Loss and Gain of Tolerance to Pancreatic Glycoprotein 2 in Celiac Disease.

PLoS ONE, 2015
BackgroundAutoantibodies against pancreatic secretory-granule membrane glycoprotein 2 (GP2) have been demonstrated in patients with Crohn's disease but recently also with celiac disease (CD).
Martin W Laass, Nadja Röber, Ursula Range, Lydia Noß, Dirk Roggenbuck, Karsten Conrad   +5 more
doaj   +1 more source

Profiling CD antigens on leukaemias with an antibody microarray [PDF]

FEBS Letters, 2009
Cluster of differentiation (CD) antigens are defined when a surface molecule found on some members of a standard panel of human cells reacts with at least one novel antibody, and there is good accompanying molecular data. Monoclonal antibodies to surface CD antigens on leukocytes have been used for flow cytometry, and more recently to construct ...
Barber, Nicole, Gez, Swetlana, Belov, Larissa, Mulligan, Stephen P., Woolfson, Adrian, Christopherson, Richard I.   +5 more
openaire   +2 more sources

Contribution of Infectious Agents to the Development of Celiac Disease

Microorganisms, 2021
The ingestion of wheat gliadin (alcohol-soluble proteins, an integral part of wheat gluten) and related proteins induce, in genetically predisposed individuals, celiac disease (CD), which is characterized by immune-mediated impairment of the small ...
Daniel Sánchez, Iva Hoffmanová, Adéla Szczepanková, Věra Hábová, Helena Tlaskalová-Hogenová   +4 more
doaj   +1 more source

Epitopes identified in GAPDH from Clostridium difficile recognized as common antigens with potential autoimmunizing properties

Scientific Reports, 2018
Clostridium difficile (CD) infections are a growing threat due to the strain resistance to antibiotic treatment and the emergence of hypervirulent strains.
Agnieszka Razim, Katarzyna Pacyga, Małgorzata Aptekorz, Gayane Martirosian, Andrzej Szuba, Edyta Pawlak-Adamska, Monika Brzychczy-Włoch, Andrzej Myc, Andrzej Gamian, Sabina Górska   +9 more
doaj   +1 more source

Label-Free Immunosensor Based on Polyaniline-Loaded MXene and Gold-Decorated β-Cyclodextrin for Efficient Detection of Carcinoembryonic Antigen

Biosensors, 2022
Multiple strategies have been employed to improve the performance of label-free immunosensors, among which building highly conductive interfaces and introducing suitable biocompatible carriers for immobilizing antibodies or antigens are believed to be ...
Qi Wang, Huaqian Xin, Zhou Wang
doaj   +1 more source

A blood-based transcriptomic signature stratifies severe Crohn’s disease and defines potentially targetable therapeutic pathways

Frontiers in Gastroenterology, 2023
IntroductionDespite advances in medical therapy, many patients with Crohn’s disease (CD) ultimately require surgery for disease management. Identifying the underlying molecular pathways for subgroup stratification is critical to the improvement of ...
Rivkah Gonsky, Evan Adams, Alka A. Potdar, Gregory Botwin, Eva Biener-Ramanujan, Dermot P. B. McGovern, Jonathan G. Braun, Phillip Fleshner, Stephan R. Targan   +8 more
doaj   +1 more source

Symposium 8: Nutrition in diabetes and celiac disease

Revista de la Sociedad Argentina de Diabetes, 2020
Symposium 8: Nutritional treatment of diabetes: new horizons Nutrition in diabetes and celiac disease The existing genetic association between type 1 Diabetes Mellitus (T1D) and Celiac Disease (CD) has led to hypothesize about a possible common ...
Marta Milikowski
doaj   +1 more source