Results 51 to 60 of about 1,666,323 (310)

Stability Assessment of Four Chimeric Proteins for Human Chagas Disease Immunodiagnosis

open access: yesBiosensors, 2021
The performance of an immunoassay relies on antigen-antibody interaction; hence, antigen chemical stability and structural integrity are paramount for an efficient assay.
Paola Alejandra Fiorani Celedon   +9 more
doaj   +1 more source

Myocardial aging as a T-cell–mediated phenomenon [PDF]

open access: yes, 2017
In recent years, the myocardium has been rediscovered under the lenses of immunology, and lymphocytes have been implicated in the pathogenesis of cardiomyopathies with different etiologies.
Abeßer, Marco   +15 more
core   +1 more source

Anti-CTLA-4 (CD 152) monoclonal antibody-induced autoimmune interstitial nephritis [PDF]

open access: yes, 2009
Targeted immune-modulating agents are entering clinical practice in many specialties, providing novel therapeutic possibilities but introducing new potential toxicities.
Clatworthy, Menna R   +4 more
core   +2 more sources

The Morphology and Phenotype of Monocyte-Macrophages When Cultured on Bionanofilms Substrates with Different Surface Relief Profiles

open access: yesBiomolecules, 2019
The effect of surface relief profiles of alkanoate-based bionanofilms to the monocyte-macrophages (MN-MPhs) from peripheral blood of patients with atherosclerosis was studied in vitro. Patients were subjected to coronary stenting.
Natalia G. Menzyanova   +7 more
doaj   +1 more source

CD Antigens 2001: Aims and Results of HLDA Workshops [PDF]

open access: yesStem Cells, 2001
aThe Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Oxford, United Kingdom; bCentre d'Immunologie, Parc Scientifique de Luminy, Cedex, France; cFaculte de Medicine de Creteil, Cedex, France; dDivision of Immunity and Infection, MRC Center for Immune Regulation, Department of Rheumatology, University of Birmingham, Edgbaston,
Curt I. Civin   +19 more
openaire   +2 more sources

Loss and Gain of Tolerance to Pancreatic Glycoprotein 2 in Celiac Disease.

open access: yesPLoS ONE, 2015
BackgroundAutoantibodies against pancreatic secretory-granule membrane glycoprotein 2 (GP2) have been demonstrated in patients with Crohn's disease but recently also with celiac disease (CD).
Martin W Laass   +5 more
doaj   +1 more source

The Gates Malaria Partnership: a consortium approach to malaria research and capacity development.

open access: yes, 2012
Recently, there has been a major increase in financial support for malaria control. Most of these funds have, appropriately, been spent on the tools needed for effective prevention and treatment of malaria such as insecticide-treated bed nets, indoor ...
Bhasin, Amit   +2 more
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Contribution of Infectious Agents to the Development of Celiac Disease

open access: yesMicroorganisms, 2021
The ingestion of wheat gliadin (alcohol-soluble proteins, an integral part of wheat gluten) and related proteins induce, in genetically predisposed individuals, celiac disease (CD), which is characterized by immune-mediated impairment of the small ...
Daniel Sánchez   +4 more
doaj   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

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