Results 181 to 190 of about 252,541 (298)

Predicted microbiome‐associated metabolic pathways are linked to immune checkpoint modulation in chronic lymphocytic leukaemia

British Journal of Haematology, EarlyView.
Summary Microbial metabolites are key regulators of host immunity, yet their functional impact in chronic lymphocytic leukaemia (CLL) remains unclear. Following up on our earlier observations of microbiome dysbiosis in CLL, we performed predictive metabolic profiling based on 16S ribosomal RNA (rRNA) sequencing of oral and stool samples collected from ...
Monika Szelest, Joanna Zaleska, Michał Kiełbus, Magdalena Paziewska, Marta Masternak, Ewa Wawrzyniak, Aleksandra Kotkowska, Monika Siemieniuk‐Ryś, Marta Morawska, Elżbieta Kalicińska, Paula Jabłonowska‐Babij, Tomasz Wróbel, Anna Wolska‐Washer, Jerzy Zdzisław Błoński, Tadeusz Robak, Krzysztof Giannopoulos   +15 more
wiley   +1 more source

CAR-T cells and CAR-Treg cells for treatment of inflammatory bowel diseases. [PDF]

EULAR Rheumatol Open
Neurath MF.
europepmc   +1 more source

Co-expression of non-signaling CARs enhances EGFRvIII-specific CAR T-cell cytotoxicity against head and neck squamous cell carcinoma. [PDF]

BMC Cancer
Grueter K, Sander N, Coen L, Hüsken S, Kleinfelder E, Haist C, Blaeschke F, Scheckenbach K, Monzel C, Hanenberg H, Wiek C.   +10 more
europepmc   +1 more source

Development of tandem canine CAR T cells to enable comparative studies of aggressive B-cell lymphoma. [PDF]

Mol Cancer Ther
Peng B, Jiang L, Lenz JA, Cesar Conti L, Rotolo A, Mason NJ, Atherton MJ.   +6 more
europepmc   +1 more source

H2-O deficiency in B cells or dendritic cells drives retrovirus-neutralizing antibody responses. [PDF]

J Virol
Dobkin J, Fink R, Lietuvninkas HB, Golovkina TV, Denzin LK.   +4 more
europepmc   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Resistance mechanisms and translational bottlenecks in CAR-T cell therapy for pediatric acute lymphoblastic leukemia: a perspective. [PDF]

Front Immunol
Xu J, Sui L, Yang W, Xu L, Shan M.
europepmc   +1 more source

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

Phenotypic Characteristics of B-Cell Subsets in Children with Allergic Diseases. [PDF]

Int J Mol Sci
Lipińska-Opałka A, Tomaszewska A, Leśnik M, Zdanowski R, Leszczyńska-Pilich M, Kalicki B.   +5 more
europepmc   +1 more source

Protein Corona‐Coated Crystal Silica From Sandstorms Amplifies Allergic Rhinitis by Regulating Epithelial Integrity in Mice and Human Nasal Epithelia

Allergy, EarlyView.
Cuishuang Dong, Xu Zhang, Haoyue Wang, Jiajing Cui, Shuai Han, Yibo Wang, Huanying Zhao, Yang Song, Yuan Zhang, Xiaobo Li   +9 more
wiley   +1 more source