Results 191 to 200 of about 53,090 (292)

Ultrasound priming gated by solid tumor hallmarks to guide CAR-T therapy. [PDF]

Sci Adv
Guo T, Zhu Z, Qu Y, Yu X, Zhu L, Wang Y, Liu K, Cui J, Dong X, Yoon CW, Kilic CY, He P, Gou S, Zeng Y, Datta P, Zhou Q, Xu H, Puri IK, Liu L, Shen K, Wang Y.   +20 more
europepmc   +1 more source

Impact of G‐CSF on Donor TCR Clonal Diversity and T Cell Function During Donor HSC Mobilisation

Cell Proliferation, EarlyView.
In this study, we found that G‐CSF mobilisation caused a reduction in TCR clonal diversity and down‐regulation of T‐cell function in donors. This may be one of the reasons for the low incidence of GVHD mediated by G‐CSF after allo‐HSCT. Source: Created in BioRender. Li https://BioRender.com/otownki.
Xinye Li, Zhixi Chen, Jie Chen, Xingwei Zhang, Jiamian Zheng, Zirui Liu, Meixue Pan, Yue Li, Bo Yu, Shaohua Chen, Jing Lai, Xianfeng Zha, Liye Zhong, Yikai Zhang, Yangqiu Li   +14 more
wiley   +1 more source

Chimeric antigen receptor technology: an emerging translational immunotherapy in nonneoplastic diseases. [PDF]

Front Immunol
Zhou S, Li Y, Zhao J, Zhan W, Zhou C, Zou Y, Li X, Cui J, Wu J, Xia J.   +9 more
europepmc   +1 more source

Extranodal Marginal Zone Lymphoma: Integrating Etiology, Microenvironment, and Genetics Into Clinical Decision‐Making

European Journal of Haematology, EarlyView.
ABSTRACT Extranodal marginal zone lymphoma (EMZL) represents a unique paradigm among indolent B‐cell neoplasms, in which lymphomagenesis is frequently driven by chronic antigenic stimulation within tissue‐specific microenvironments. Persistent infectious or autoimmune triggers promote the development of ectopic lymphoid tissue and sustain B‐cell ...
Mamdouh Skafi, Santino Caserta, Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Marco Fiorillo, Eugenio Lucia, Graziella D'Arrigo, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Maria Eugenia Alvaro, Giovanni Tripepi, Fortunato Morabito, Massimo Gentile   +15 more
wiley   +1 more source

Kidney Transplantation in Two Highly Sensitized Candidates after CAR T-Cell Therapy. [PDF]

N Engl J Med
Bhoj VG, Kaminski M, Zhao H, Jackson K, Wang W, Liu C, Montgomery RA, Ali N, Mangiola M, Spitzer TR, Safa K, Pattanayak V, Taj R, Chiu J, Bui TM, Sonnenberg EM, Markmann JF, Milone MC, June CH, Siegel DL, Fraietta JA, Gonzalez V, Locci M, Palmer M, Monos D, Hwang WT, Sledge T, Bridges ND, Goldstein JS, Odim J, Sweet SC, Besharatian BD, Hussain SM, Brown NK, Kamoun M, Garfall AL, Naji A.   +36 more
europepmc   +1 more source

169. Clinically Adaptable CD19-Specific Chimeric Antigen Receptor [PDF]

Molecular Therapy, 2014
openaire   +1 more source

Safety profile of chimeric antigen receptor T‐cell therapy in relapsed/refractory multiple myeloma: A systematic review and meta‐analysis of proportions from clinical trials

British Journal of Haematology, EarlyView.
Charalampos Filippatos, Ioannis Ntanasis‐Stathopoulos, Areti Voulomenou, Panagiotis Malandrakis, Efstathios Kastritis, Maria Gavriatopoulou, Meletios‐Athanasios Dimopoulos, Evangelos Terpos   +7 more
wiley   +1 more source

The Class I Scavenger Receptors CD5 and CD6 Play a Role in the Early Peritoneal Immune Response to <i>Echinococcus granulosus</i> Tegumental Antigens. [PDF]

Int J Mol Sci
García-Luna J, Català C, Dematteis S, Lozano F, Velasco-De-Andrés M, Mourglia-Ettlin G.   +5 more
europepmc   +1 more source

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala, Anna Maria Della Corte, Angela Bertolini, Marisa Gorrese, Francesca Picone, Bianca Serio, Danilo De Novellis, Laura Mettivier, Luca Pezzullo, Maria Carmen Martorelli, Denise Morini, Matteo D'Addona, Bianca Cuffa, Carmine Selleri, Valentina Giudice   +14 more
wiley   +1 more source

From CAR-T to CAAR-T: redefining targeting strategies in B-cell malignancies through idiotype-directed cellular therapy. [PDF]

Front Immunol
Buczek T, Butrym A.
europepmc   +1 more source