Regional and Sex‐Dependent Immune Profiling Across the Colon in A Mouse Model of Ulcerative Colitis
At baseline, males have higher IL‐10, TH17 cytokines, and higher macrophages, neutrophils, and CD8+ cells in the medial and distal colon. Whereas females displayed increasing macrophages, lower TNF‐α, and higher IL‐1β, IL‐17A, and dendritic cells in the cecum and proximal colon.
Diane M. Tshikudi +6 more
wiley +1 more source
CAR-T cell therapy: A new dawn in the treatment of autoimmune disease. [PDF]
Yan S, Zhu X, Xiao Y.
europepmc +1 more source
Manufacturing and clinical applications of non‐CAR‐T immune effector cells
Transfusion, EarlyView.
Thane Kubik +2 more
wiley +1 more source
Multiphysics‐Driven Assembly of Biomimetic Vesicles
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko +16 more
wiley +1 more source
CAR-T cells targeting CD19 for the treatment of ANCA vasculitis. [PDF]
Lodka D, Schreiber A.
europepmc +1 more source
Antibody Deficiency in Xeroderma Pigmentosum. [PDF]
Rossmanith R +3 more
europepmc +1 more source
Chimeric antigen receptor T-cell therapy for stiff-person syndrome: bridging innovation and clinical challenges in neuroimmunology. [PDF]
Wickel J +6 more
europepmc +1 more source
CRISPR-mediated generation of a tumor-associated antigen-deficient Raji platform to investigate antigen loss in CAR-T cell therapy. [PDF]
Iyer AR +8 more
europepmc +1 more source
CAR T cells: the missing piece needed to improve outcomes for children with cancer? [PDF]
Mackall C.
europepmc +1 more source

