Results 231 to 240 of about 33,041 (261)

CD20 Antigen May Be Expressed by Reactive or Lymphomatous Cells of Transformed Mycosis Fungoides

American Journal of Surgical Pathology, 2013
Mycosis fungoides (MF), the most common primitive cutaneous T-cell lymphoma, can undergo transformation in about 10% of cases. Transformed mycosis fungoides (T-MF) is often associated with the appearance of a CD20 component. The aim of this study was to analyze whether such cells are reactive or lymphomatous and to evaluate their prognostic impact ...
Marie-Laure, Jullié, Martina, Carlotti, Alexandre, Vivot, Marie, Beylot-Barry, Nicolas, Ortonne, Eric, Frouin, Agnes, Carlotti, Anne, de Muret, Brigitte, Balme, Frédéric, Franck, Jean-Philippe, Merlio, Béatrice, Vergier   +11 more
openaire   +2 more sources

Generation and functional comparison of anti-CD20 chimeric antigen receptors

2019
Chimeric antigen receptor (CAR) T-cell therapy has proven effective, particularly in targeting relapsed, refractory haematological malignancies. However, optimal CAR design is not fully understood. It is known that the antigen epitope position, affinity of interaction and the length of the CAR construct can all impact function, but these factors often ...
openaire   +2 more sources

Neoplastic Epithelial Cells in a Subset of Human Thymomas Express the B Cell-Associated CD20 Antigen

The American Journal of Surgical Pathology, 1992
A series of 36 human thymomas have been immunohistochemically analyzed using a panel of antibodies recognizing B-cell markers including CD20. Most thymomas exhibiting the cortical pattern, according to the criteria of Marino and Muller-Hermelink, were characterized by areas of medullary differentiation containing variable numbers of CD20+ B lymphocytes,
Facchetti Fabio, MARTIGNONI, Guido, MOMBELLO, Aldo, Lestani Maurizio, SCARPA, Aldo, MENESTRINA, Fabio, PIZZOLO, Giovanni, MONTRESOR, Ettore, Castelli Paola, Truini Mauro   +9 more
openaire   +4 more sources

Structure of the gene encoding the human B lymphocyte differentiation antigen CD20 (B1).

The Journal of Immunology, 1989
Abstract The CD20 (B1) molecule is a differentiation Ag found only on the surface of B lymphocytes. This structurally unique phosphoprotein plays a role in the regulation of human B cell proliferation and differentiation. In this report genomic DNA clones containing the human CD20 gene were isolated and the structure of the CD20 gene ...
T F, Tedder, G, Klejman, S F, Schlossman, H, Saito   +3 more
openaire   +2 more sources

CD20 antigen imaging with ¹²⁴I-rituximab PET/CT in patients with rheumatoid arthritis.

Human antibodies, 2011
Visualization of the CD20-antigen expression could provide a tool to localize sites of inflammation and could be of additive value in the diagnosis, and subsequently, in the treatment follow-up of patients with rheumatoid arthritis. In this study, an anti-CD20 monoclonal antibody, rituximab (Mabthera®), was radiolabeled with ¹²⁴Iodine.
L, Tran, A D R, Huitema, M H, van Rijswijk, H J, Dinant, J W, Baars, J H, Beijnen, W V, Vogel   +6 more
openaire   +2 more sources

CD20 antigen imaging with 124I-rituximab PET/CT in patients with rheumatoid arthritis

Human Antibodies, 2011
Introduction: Visualization of the CD20-antigen expression could provide a tool to localize sites of inflammation and could be of additive value in the diagnosis, and subsequently, in the treatment follow-up of patients with rheumatoid arthritis. In this study, an anti-CD20 monoclonal antibody, rituximab (Mabthera®), was radiolabeled with 124Iodine. We
Tran, L., Huitema, A.D.R., van Rijswijk, M.H., Dinant, H.J., Baars, J.W., Beijnen, J.H., Vogel, W.V.   +6 more
openaire   +1 more source

Effects of cytokines on CD20 antigen expression on tumor cells from patients with chronic lymphocytic leukemia

Leukemia Research, 2000
Anti-CD20 antibody is an established treatment for low-grade non-Hodgkin's lymphoma (NHL). Augmenting the expression of CD20 antigen on the tumor cells may increase the cell kill and therefore increase the effectiveness of the antibody. To study this, we incubated peripheral blood lymphocytes from CLL patients with the following cytokines: EPO, SCF ...
P, Venugopal, S, Sivaraman, X K, Huang, J, Nayini, S A, Gregory, H D, Preisler   +5 more
openaire   +2 more sources

[Distribution and force spectroscopy of CD20 antigen-antibody binding on the B cell surface].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2012
The lower expression of CD20 antigen molecules on the B cell membrane is the primary characteristic of B-chronic lymphocytic leukemia (B-CLL). In this paper, we combined laser scanning confocal microscopy (LSCM) and quantum dots labeling to detect the expression and distribution of CD20 molecules on CD20+B lymphocyte surface.
Qiulan, Wang, Yuhong, Lu, Shengpu, Li, Mu, Wang, Jiye, Cai   +4 more
openaire   +1 more source

CD20 as a gatekeeper of the resting state of human B cells

Proceedings of the National Academy of Sciences of the United States of America, 2021
Kathrin Klasener, Julia Jellusova, Geoffroy Andrieux   +2 more
exaly  

[Expression of CD68 CD45RO CD20 and proliferating cell nuclear antigen in nasal polyps].

Zhonghua er bi yan hou ke za zhi, 2005
To study the cellular expression of CD45RO, CD20, CD68 and proliferating cell nuclear antigen (PCNA) in nasal polyps.Nasal polyp tissues from 50 patients were evaluated for cellular expression of CD45RO, CD20, CD68 and PCNA using immunohistochemistry SP by counting the average number in 5 chosen high-power fields, Histopathological observations were ...
Xu, Wu, Li-fen, Wang, Yu-hua, Zang
openaire   +1 more source