Results 51 to 60 of about 214,371 (284)

The HPB-AML-I cell line possesses the properties of mesenchymal stem cells

Journal of Experimental & Clinical Cancer Research, 2010
Background In spite of its establishment from the peripheral blood of a case with acute myeloid leukemia (AML)-M1, HPB-AML-I shows plastic adherence with spindle-like morphology.
Tatsumi Eiji, Kurimoto Chiyo, Jauharoh Siti NA, Kasagi Shimpei, Kawano Seiji, Sugimoto Takeshi, Ardianto Bambang, Morikawa Keiko, Kumagai Shunichi, Hayashi Yoshitake   +9 more
doaj   +1 more source

Expression of the human leukocyte adhesion molecule, LAM1. Identity with the TQ1 and Leu-8 differentiation antigens.

Journal of Immunology, 1990
The LAM1 molecule is a member of the new family of cellular adhesion/homing molecules that contain a lectin-like domain at their amino-terminal end followed by an epidermal growth factor-like domain and short consensus repeat units like those found in C3/
T. Tedder, Ann C. Penta, H. Levine, A. Freedman   +3 more
semanticscholar   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

The Superior Ability of Human BDCA3+ (CD141+) Dendritic Cells (DCs) to Cross-Present Antigens Derived From Necrotic Lung Cancer Cells

Frontiers in Immunology, 2020
Dendritic cells (DCs) play a key role in initiating and regulating the immune responses to pathogens, self-antigens, and cancers. Human blood DCs comprise a family of different subsets: plasmacytoid DCs (pDCs) and CD16+, CD1c/BDCA1+, and BDCA3+ (CD141 ...
Fei-fei Gu, Kai Zhang, Li-li Ma, Yang-yang Liu, Chang Li, Yue Hu, Qi-fan Yang, Jin-yan Liang, Yu-lan Zeng, Yan Wang, Li Liu   +10 more
doaj   +1 more source

Cross-Activation of Hemichannels/Gap Junctions and Immunoglobulin-Like Domains in Innate–Adaptive Immune Responses

Frontiers in Immunology, 2022
Hemichannels (HCs)/gap junctions (GJs) and immunoglobulin (Ig)-like domain-containing proteins (IGLDCPs) are involved in the innate–adaptive immune response independently.
Jiang-Hui Meng, Jiang-Hui Meng, Chang-Xu Chen, Chang-Xu Chen, Mohammad R. Ahmadian, Hong Zan, Kai-Jun Luo, Kai-Jun Luo, Jean X. Jiang   +8 more
doaj   +1 more source

Differentiation antigens identify subpopulations of rabbit T and B lymphocytes. Definition by flow cytometry

Journal of Experimental Medicine, 1983
A panel of six monoclonal antibodies produced against cell surface glycoproteins of a rabbit T lymphocyte line was used with flow cytometry to define rabbit lymphocyte subpopulations.
S. Jackson, T. Chused, J. Wilkinson, W. Leiserson, T. Kindt   +4 more
semanticscholar   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

9-cis-retinoic acid signaling in Sertoli cells regulates their immunomodulatory function to control lymphocyte physiology and Treg differentiation

Reproductive Biology and Endocrinology
Background Testis is an immune privileged organ, which prevents the immune response against sperm antigens and inflammation. Testicular cells responsible for immune tolerance are mainly Sertoli cells, which form the blood-testis barrier and produce ...
Alicja Kamińska, Laura Pardyak, Sylwia Lustofin, Karolina Gielata, Zbigniew Arent, Agnieszka Pietsch-Fulbiszewska, Anna Hejmej   +6 more
doaj   +1 more source

Multi-omics approaches reveal the mechanisms underlying the interaction between cyst fluid of Echinococcus granulosus and host immune cells

Frontiers in Immunology
BackgroundEchinococcus granulosus cyst fluid (EgCF) is a complex mixture of parasite’s containing a variety of antigens. Th9 cells are a newly reported subpopulation of Th cells whose primary function is to secrete IL-9 and exert biological effects ...
Rongdong He, Rongdong He, Ruofeng Yan, Yuanchun Shi, Aili Aierken, Xue Zhang, Hao Wen, Hao Wen, Kalibixiati Aimulajiang   +8 more
doaj   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source