Results 31 to 40 of about 156,998 (310)
Journal of Extracellular Vesicles, 2022 Tumour cells are characterized by having lost their differentiation state. They constitutively secrete small extracellular vesicles (sEV) called exosomes when they come from late endosomes.
Michel Record +14 more
doaj +1 more source
Immunoregulatory soluble CTLA-4 modifies effector T cell responses in systemic lupus erythematosus [PDF]
, 2016 Acknowledgments This work was supported by Arthritis Research UK (Grant no. 19282). We are grateful to Dr. Nick Fluck for his invaluable support in recruiting patients for the study, and Mrs.
Barker, Robert N. +6 more
core +3 more sources
Marine Life Science & Technology, 2022 AbstractCluster of differentiation (CD) antigens are cell surface molecules expressed on leukocytes and other cells associated with the immune system. Antibodies that react with CD antigens are known to be one of the most essential tools for identifying leukocyte subpopulations.
Tian, Hong-fei +5 more
openaire +2 more sources
PLoS ONE, 2010 BackgroundDendritic cells capture antigens through PRRs and modulate adaptive immune responses. The type of adaptive immune T cell response generated is dependent upon the type of PRR activated by the microbes.
Sudhanshu Agrawal +2 more
doaj +1 more source
HLA Variation and SARS-CoV-2 Specific Antibody Response
Viruses, 2023 Differences in SARS-CoV-2-specific immune responses have been observed between individuals following natural infection or vaccination. In addition to already known factors, such as age, sex, COVID-19 severity, comorbidity, vaccination status, hybrid ...
Dawit Wolday +6 more
doaj +1 more source
Journal for ImmunoTherapy of Cancer, 2021 Background A major current challenge is to exploit tertiary lymphoid structures (TLSs) to promote the lymphocyte infiltration, activation and differentiation by tumor antigens to increase antitumor immune responses.
Shu-Mei Yan +9 more
doaj +1 more source
Structure and function of T lymphocyte differentiation antigens
Trends in Genetics, 1986 Abstract In addition to the T cell reception for antigen, T lymphocytes express a variety of additional T cell-specific surface molecules which are involved in recognition, activation and function. The structure, evolutionary relationship and functions of four of these T cell differentiation antigens are discussed.
openaire +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Human T lymphocyte differentiation antigens: Effects of blood sample storage on LEU antibody binding [PDF]
Cytometry, 1983 AbstractCurrent studies of human T lymphocytes and their subsets often use quantitative immunofluorescence analysis with monoclonal antibodies against cell surface antigens. With storage of whole blood or separated mononuclear cells for more than a few hours we have found marked changes in lymphocyte analysis using a fluorescence activated cell sorter (
P A, Hensleigh +2 more
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source