Results 11 to 20 of about 156,998 (310)

The Role of Adaptor Proteins in the Biology of Natural Killer T (NKT) Cells

open access: yesFrontiers in Immunology, 2019
Adaptor proteins contribute to the selection, differentiation and activation of natural killer T (NKT) cells, an innate(-like) lymphocyte population endowed with powerful immunomodulatory properties.
Evelyn Gerth, Jochen Mattner
doaj   +1 more source

Enforced expression of the transcriptional coactivator OBF1 impairs B cell differentiation at the earliest stage of development. [PDF]

open access: yesPLoS ONE, 2008
OBF1, also known as Bob.1 or OCA-B, is a B lymphocyte-specific transcription factor which coactivates Oct1 and Oct2 on B cell specific promoters. So far, the function of OBF1 has been mainly identified in late stage B cell populations. The central defect
Alain Bordon   +7 more
doaj   +1 more source

ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS

open access: yesМедицинская иммунология, 2014
. The aim of the present research was to study the expression of Fas-receptor and differentiation antigens CD3, CD4, CD8, CD16, CD20 on mononuclear cells of peripheral blood in the group of people with asimptomatic Zn-deficiency caused by geochemical ...
L. M. Karzakova
doaj   +1 more source

Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine

open access: yesCase Reports in Medicine, 2016
Indoleamine 2,3-dioxygenase (IDO) expression in dendritic cells (DCs) inhibits T-cell activation and promotes T-cell differentiation into regulatory T-cells.
Mouldy Sioud   +5 more
doaj   +1 more source

Production of Abzymes in Th, CBA, and C57BL/6 Mice before and after MOG Treatment: Comparing Changes in Cell Differentiation and Proliferation

open access: yesBiomolecules, 2019
Till yet there is no data concerning mechanisms of autoimmune diseases development. Experimental autoimmune encephalomyelitis (EAE) prone C57BL/6 (T- and B-lymphocyte response), non-autoimmune CBA, and Th mice with T cell response were immunized with ...
Kseniya S. Aulova   +11 more
doaj   +1 more source

II. Detection of an antigen on resting T cells down-regulated after activation [PDF]

open access: yes, 1987
The expression of an antigen on porcine T lymphocytes detected by murine monoclonal antibody (mAb) 8/1 was investigated by functional studies and dual-parameter immunofluorescence.
Bühring, Hans-Jörg   +4 more
core   +1 more source

Generation and Characterization of a Murine Monoclonal Antibody Specific for the Human T1-Cd5 Molecule

open access: yesThe International Journal of Biological Markers, 1987
Murine monoclonal antibodies (MoAbs) have found widespread applications in the characterization of the molecular and functional features of lymphocyte differentiation antigens.
Federico Genzano   +8 more
doaj   +1 more source

New insights into Blimp-1 in T lymphocytes: a divergent regulator of cell destiny and effector function

open access: yesJournal of Biomedical Science, 2017
B lymphocyte-induced maturation protein-1 (Blimp-1) serves as a master regulator of the development and function of antibody-producing B cells. Given that its function in T lymphocytes has been identified within the past decade, we review recent findings
Shin-Huei Fu   +4 more
doaj   +1 more source

The synergistic and enhancive effects of IL-6 and M-CSF to expand and differentiate functional dendritic cells from human monocytes under serum-free condition

open access: yesJournal of Biological Engineering, 2023
Background Dendritic cells (DCs) are differentiated from monocytes, and have a strong ability to perform phagocytosis, present antigens and activate T cell immune response.
Chao-Ling Yao, Tsung-Yu Tseng
doaj   +1 more source

Functional characterization of infiltrating T lymphocytes in human hepatic allografts [PDF]

open access: yes, 1986
We have employed recently developed techniques in T-cell culturing to study the nature and function of infiltrating hepatic allograft T cells. Using the rationale that intragraft T cells are activated during cell mediated damage to the allograft, we were
Adriana Zeevi   +53 more
core   +1 more source

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