Results 1 to 10 of about 156,998 (310)
Expression of the CD6 T lymphocyte differentiation antigen in normal human brain [PDF]
Journal of Neuroimmunology, 1990 Antigens shared by the immune and central nervous systems (CNS) have been described repeatedly. The present study reports the expression of the CD6 lymphocyte differentiation antigen in normal human brain evidenced by immunohistochemistry and Northern ...
Funke, Ilona +4 more
core +5 more sources
The Effect of Immunosuppressive Adjuvant Kynurenine on Type 1 Diabetes Vaccine
Frontiers in Immunology, 2021 Inducing antigen-specific tolerance is a promising treatment for preventing or reversing Type 1 diabetes (T1D). In contrast to a vaccine that induces immune responses against pathogens, a tolerogenic vaccine can suppress immunity against antigens causing
Jing Sun +12 more
doaj +1 more source
The role of immune checkpoints in cardiovascular disease
Frontiers in Pharmacology, 2022 Immune checkpoint inhibitors (ICI) are monoclonal antibodies which bind to immune checkpoints (IC) and their ligands to prevent inhibition of T-cell activation by tumor cells.
Laura I. Yousif +4 more
doaj +1 more source
Assessing in vitro and in vivo Trogocytosis By Murine CD4+ T cells
Bio-Protocol, 2020 Recognition of antigens by lymphocytes (B, T, and NK) on the surface of an antigen-presenting cell (APC) leads to lymphocyte activation and the formation of an immunological synapse between the lymphocyte and the APC.
Jim Reed, Scott Wetzel
doaj +1 more source
Frontiers in Immunology, 2022 BackgroundThe Human Cell Differentiation Molecules (HCDM) organizes Human Leukocyte Differentiation Antigen (HLDA) workshops to test and name clusters of antibodies that react with a specific antigen.
Daniela Kužílková +8 more
doaj +1 more source
Acquisition of cytotoxic T lymphocyte-specific carbohydrate differentiation antigens. [PDF]
The Journal of experimental medicine, 1985 Cytotoxic T cell (CTL)-specific activation antigens, termed CT determinants, have been detected by monoclonal antibodies (mAb) that inhibit CTL function. At the cell surface, the CT antigens are associated with the T200 glycoproteins and two other proteins of Mr 140,000 and 85,000 and are present on a secreted protein, gp155.
L, Lefrancois +3 more
openaire +2 more sources
Molecular Therapy: Oncolytics, 2021 Recently, oncolytic vaccinia viruses (VACVs) have shown their potential to provide for clinically effective cancer treatments. The reason for this clinical usefulness is not only the direct destruction of infected cancer cells but also activation of ...
Stephanie Riederer +5 more
doaj +1 more source
Regulated progression of B lymphocyte differentiation from cultured fetal liver. [PDF]
, 1987 Lymphoid fetal liver cultures (LFLC) are long-term, nontransformed cultures of early B lymphoid lineage cells which appear developmentally blocked at the pre-B stage in vitro.
Denis, KA, Dorshkind, K, Witte, ON
core +2 more sources
Genetic deletion of Mst1 alters T cell function and protects against autoimmunity. [PDF]
PLoS ONE, 2014 Mammalian sterile 20-like kinase 1 (Mst1) is a MAPK kinase kinase kinase which is involved in a wide range of cellular responses, including apoptosis, lymphocyte adhesion and trafficking.
Konstantin V Salojin +24 more
doaj +1 more source
Simultaneous expression of CD4 and CD8 antigens by a substantial proportion of resting porcine T lymphocytes [PDF]
, 1987 The existence of four subpopulations in resting porcine T lymphocytes is documented. In addition to the two known subpopulations which are typified by a mutually exclusive expression of either the CD8 or the CD4 differentiation antigen, CD4-CD8+ and CD4 ...
Bevan +19 more
core +3 more sources