Results 201 to 210 of about 8,144,327 (289)

Associations of Inherited Chromosomally-Integrated Human Herpesvirus 6 With Dementia Incidence, Inflammation, and Other Dementia Risk Factors in the UK Biobank. [PDF]

J Med Virol
Qiya Z, Mandic M, Waterboer T, Ruijie X, Brenner H, Schöttker B.   +5 more
europepmc   +1 more source

Integration of scRNA‐Seq and scATAC‐Seq Revealed the Role of lncRNA RP11‐661C8.2 by Promoting EMT in Clear Cell Renal Cell Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Long noncoding RNAs (lncRNAs) play an important role in tumor progression. However, most of the previously discovered lncRNAs that promote or inhibit tumor progression were derived from bulk RNA‐seq results. Data from single‐cell RNA sequencing (scRNA‐seq) and single‐cell assay for transposase‐accessible chromatin using sequencing (scATAC‐seq)
Jizhen Cen, Xuefang Liang, Zheng Wen, Shengzhu Huang, Jiaping Li, Haibiao Yan, Kaiqiang Tang, Guifen Zhou, Ning Liang, Qi Zheng, Cheng Su, Zengnan Mo, Zhenyuan Yu   +12 more
wiley   +1 more source

Non-PF4/heparin-binding, platelet-activating antibodies in heparin-induced thrombocytopenia. [PDF]

Blood
Zhou L, Cao A, Zhu W, Villalobos-Garcia D, Marchan M, Curtis B, Rauova L, Poncz M, Aster R, Padmanabhan A, Wang D, Wen R.   +11 more
europepmc   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Investigating human platelet antigens and antibodies in pregnancy: An 11-year experience from a Canadian reference laboratory. [PDF]

Vox Sang
Tordon B, Clarke G, Wong J, Peregrin A, Gupta A.   +4 more
europepmc   +1 more source

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

Medicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo, Kaeun Chae, Jueun Lee, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Cell Membrane-Coated Nanoparticles as Biomimetic Drug Delivery Systems: Design, Therapeutic Applications, and Translational Challenges. [PDF]

Pharmaceutics
Jacob S, Varkey NR, Rao R, Shinu P, Khanam R.   +4 more
europepmc   +1 more source

Human platelet specific antigens and their importance.

Indian pediatrics, 2004
Dpika, Mohanty, Bipin, Kulkarni, Kanjaksha, Ghosh, Sona, Nair, Amit, Khare   +4 more
openaire   +1 more source

Aptamer–Based Targeted Protein Degradation: Mechanistic Principles, Delivery Strategies, and Translational Opportunities

Medicinal Research Reviews, EarlyView.
ABSTRACT Targeted elimination of pathogenic proteins remains a fundamental challenge in therapeutic intervention, particularly for proteins considered “undruggable” by conventional inhibition‐based approaches. Aptamer–based targeted protein degradation (TPD) has emerged as a versatile strategy that leverages the high specificity, structural ...
Ambrin Malik, Suyeon Son, Jaesung Lee, Ki Soo Park   +3 more
wiley   +1 more source

Beyond Hemostasis: Platelets' Multifaceted Functions in Immune Responses. [PDF]

Life (Basel)
Doolittle WKL, Walters EL, Maitta RW.
europepmc   +1 more source