Results 111 to 120 of about 1,951,078 (347)

Impaired Transporter Associated with Antigen Processing-Dependent Peptide Transport during Productive EBV Infection [PDF]

, 2005
Maaike E. Ressing, Sinéad E. Keating, Daphne van Leeuwen, Danijela Koppers‐Lalic, Isabel Y. Pappworth, Emmanuel J. H. J. Wiertz, Martin Rowe   +6 more
openalex   +1 more source

Large Scale Ex Vivo Expansion of γδ T cells Using Artificial Antigen-presenting Cells

, 2022
Justin C. Boucher, Bin Yu, Gongbo Li, Bishwas Shrestha, David A. Sallman, Ana Marie Landin, Cheryl A. Cox, Kumar Karyampudi, Claudio Anasetti, Marco L. Davila, Nelli Bejanyan   +10 more
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Benign tumors broaden the field of application for immunotherapy

Frontiers in Immunology
Immunotherapy has shown significant potential for treating malignancies. Not yet widely considered is the opportunity to employ immunotherapy for the treatment of benign tumors.
Mohamed A. Youssef, Mohamed A. Youssef, Hisham Al-Sharif, Brian T. McGrath, Maria M. Picken, I. Caroline Le Poole   +5 more
doaj   +1 more source

Relationship Between Rotavirus P[6] Infection in Korean Neonates and Histo-Blood Group Antigen: a Single-Center Study

, 2020
Su Kyung Lee, Su Jin Oh, Seoheui Choi, Soo‐Han Choi, Seon Hee Shin, Eun Jin Lee, Eun‐Jung Cho, Jungwon Hyun, Hyun Soo Kim   +8 more
openalex   +1 more source

The rapid generation of recombinant functional monoclonal antibodies from individual, antigen-specific bone marrow-derived plasma cells isolated using a novel fluorescence-based method [PDF]

, 2013
Alison Clargo, Ashley R Hudson, Welcome Ndlovu, Rebecca J Wootton, Louise A Cremin, Victoria O’Dowd, Carla R. Nowosad, Dale Starkie, Sophie P. Shaw, Joanne Compson, Dominic P. White, Brendon MacKenzie, James Snowden, Laura E Newnham, Michael Wright, Paul E. Stephens, Meryn Griffiths, Alastair D. G. Lawson, Daniel Lightwood   +18 more
openalex   +1 more source

Alternative tumour-specific antigens

Nature Reviews. Cancer, 2019
Christof C. Smith, Sara R. Selitsky, Shengjie Chai, P. Armistead, B. Vincent, J. Serody   +5 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

HER2-Specific Chimeric Antigen Receptor–Modified Virus-Specific T Cells for Progressive Glioblastoma

, 2017
Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Kevin Bielamowicz, Mamta Kalra, Daniel Landi, Catherine Robertson, Tara Gray, Oumar Diouf, Amanda Wakefield, Alexia Ghazi, Claudia Gerken, Zhongzhen Yi, Aidin Ashoori, Meng-Fen Wu, Hao Liu, Cliona M. Rooney, Gianpietro Dotti, Adrian P. Gee, Jack Su, Yvonne Kew, David S. Baskin, Yi Jonathan Zhang, Pamela New, Bambi Grilley, Milica Stojakovic, John Hicks, Suzanne Z. Powell, Malcolm K. Brenner, Helen E. Heslop, Robert G. Grossman, Winfried S. Wels, Stephen Gottschalk   +32 more
openalex   +2 more sources