Results 121 to 130 of about 4,370 (170)

Visceral Leishmaniasis: Integrated In Silico Screening of Djiboutian Medicinal Plant Phytoconstituents Targeting <i>Leishmania donovani</i> and <i>Leishmania infantum</i>. [PDF]

Pharmaceuticals (Basel)
Mohamed Abdoul-Latif F, Bouribab A, Mohamed H, El Bouamri L, Rossafi B, Guerguer F, Yamari I, Ismael YA, Jutur PP, Chtita S.   +9 more
europepmc   +1 more source

Fagonia indica mediated biosynthesis of iron oxide nanoparticles with enhanced antimicrobial and therapeutic potential. [PDF]

Discov Nano
Kamal A, Nazish M, Kamal K, Abdelmohsen SAM, Alarfj SF, Rebouh NY, Muminov M, Razak SA, Xakimov N, Rzayev O, Mengistie YD, Zaman W.   +11 more
europepmc   +1 more source

Multiscale-Aware Graph Embedding Approach Uncovers LC-61, a Potent Anti-<i>Leishmania infantum</i> Compound. [PDF]

J Chem Inf Model
Costa VAF, Carvalho AMDS, Chelucci RC, Mendonça de Melo FDS, Felizardo GSS, Bernardes CAC, Martin HJ, Braga RC, Charneau S, Muratov EN, Andricopulo AD, Bastos IMD, Neves BJ.   +12 more
europepmc   +1 more source

Synthesis and Antileishmanial Activity of Cinnamic Acid-Amantadine Amides. [PDF]

ACS Omega
Fernandes ÉB, de Freitas CS, Silva Viana LP, Moreira da Silva C, Guedes NA, Romão W, Lacerda V, Dos Santos NA, de Oliveira FM, da Silva DA, Cerceau CI, de Oliveira MB, Belarmino WDS, Campos Serpa QH, de Oliveira OV, Costa AV, Coelho EAF, Teixeira RR.   +17 more
europepmc   +1 more source

Antileishmanial and Immunomodulatory Activity of Paclitaxel and Docetaxel Combined with Miltefosine and Paromomycin. [PDF]

Int J Mol Sci
Melcón-Fernández E, Balaña-Fouce R, García-Estrada C, Reguera RM, Fernández-Rubio C, Cendón-Álvarez M, Pérez-Pertejo Y.   +6 more
europepmc   +1 more source

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Antileishmanial agents part-IV: synthesis and antileishmanial activity of novel terpenyl pyrimidines

European Journal of Medicinal Chemistry, 2005
Some novel N- and O-substituted terpenyl pyrimidines 4 (a-j) have been synthesized and screened for in vitro antileishmanial activity profile in promastigote model. Some of the compounds exhibited 100% inhibition at 10 microg ml(-1) concentration.
Naveen Chandra, Neena Goyal, S N Suryawanshi   +2 more
exaly   +3 more sources

Natural and synthetic coumarins as antileishmanial agents: A review

European Journal of Medicinal Chemistry, 2020
The neglected tropical disease leishmaniasis is still a major public health problem that affects millions of people worldwide. Related to poor-living conditions, this vector-borne disease presents multiple clinical manifestations - from asymptomatic to systemic conditions.
Guilherme Arraché Gonçalves, Gustavo Machado Das Neves, Luciano Porto Kagami   +2 more
exaly   +3 more sources

Plants as Antileishmanial Agents: Current Scenario

Phytotherapy Research, 2016
Leishmaniasis is a clinical manifestation caused by the parasites of the genus Leishmania. Plants are reservoirs of bioactive compounds, which are known to be chemically balanced, effective and least injurious as compared with synthetic medicines. The current resistance and the toxic effects of the available drugs have brought the trend to assess the ...
Nazif Ullah, Akhtar Nadhman, Arshad Islam   +2 more
exaly   +3 more sources

Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents

European Journal of Medicinal Chemistry, 2007
Several compounds of great pharmacological interest contain the triazole and imidazole rings. In order to find new drugs with antileishmanial activity we have synthesized and evaluated new imidazole and triazole compounds carrying either the carbaldehyde or the difluoromethylene functionalities against promastigote forms of Leishmania amazonensis ...
Sabrina Baptista Ferreira, Nubia Boechat, Marilene M Canto-Cavalheiro   +2 more
exaly   +3 more sources