The intragraft vascularized bone marrow induces secondary donor-specific mystacial pad allograft tolerance [PDF]
IntroductionVascularized bone marrow (VBM) is essential in tolerance induction through chimerism. We hypothesized that the inclusion of VBM contributes to the induction of mystacial pad allotransplantation tolerance.MethodIn this study, 19 VBM, nine ...
Cheng-Hung Lin +6 more
doaj +2 more sources
Usefulness of valacyclovir prophylaxis for cytomegalovirus infection after anti-thymocyte globulin as rejection therapy [PDF]
Background/Aims Anti-thymocyte globulin (ATG) treatment for acute T-cell mediated rejection (TCMR) can increase the risk of cytomegalovirus (CMV) infection.
Eun Jeong Ko +3 more
doaj +1 more source
Key Clinical Message This report describes a rare case of developing Guillain–Barre syndrome (GBS) following receiving rabbit antithymocyte globulin (ATG) after kidney transplantation to prevent acute allograft rejection in a 34‐year‐old man. The patient
Farnaz Tavakoli +3 more
doaj +1 more source
Bioimaging of alloantigen-stimulated regulatory T cells in rat vascularized composite allotransplantation. [PDF]
BACKGROUND:Tipping the balance toward regulatory T cells (Tregs) through adoptive cell therapy has shown promise to induce transplantation tolerance. Although such strategy has been explored in many mice organ transplantation studies, less knowledge was ...
Hui-Yun Cheng +9 more
doaj +1 more source
In this study, we sought to test whether introduction of fetal cells into the adult rat thymus would promote immunotolerance to subsequent donor-type allografts in the injured spinal cord.
Daniel P. Theele, Paul J. Reier Ph.D.
doaj +1 more source
Tacrolimus rescue therapy for renal allograft rejection - Five-year experience [PDF]
Over the 5 year period from 7/14/1989 until 5/24/1994, we have attempted graft salvage with tacrolimus conversion in a total of 169 patients (median age 33 years, range 2-75 years) with ongoing rejection on baseline CsA immunosuppression after failure of
Demetris, AJ +12 more
core +1 more source
Hepatotoxicity induced by horse ATG and reversed by rabbit ATG: a case report
Background The use of antilymphocyte agents has improved patient and graft survival in hematopoietic stem cell and solid organ transplantation but has been associated with the development of short-term toxicities as well as long-term complications.
Al-Anazi Khalid A +5 more
doaj +1 more source
Avenues of future research in homotransplantation of the liver with particular reference to hepatic supportive procedures, antilymphocyte serum, and tissue typing [PDF]
Three general areas of research which bear on the developing field of liver transplantation are reviewed. These are: (1) the prospects of obtaining better immunosuppression with particular reference to heterologous antilymphocyte serum; (2) the possible ...
Anderson +31 more
core +1 more source
Heart Allograft Tolerance Induced and Maintained by Vascularized Hind-Limb Transplant in Rats
Organ/tissue transplantation has become an effective therapy for end-stage diseases. However, immunosuppression after transplantation may cause severe side effects. Donor-specific transplant tolerance was proposed to solve this problem. In this study, we
Quan Liu +5 more
doaj +1 more source
Successful Single Donor Islet Allotransplantation in the Streptozotocin Diabetes Rat Model
The objective of this study was to define pretransplant islet culture conditions for optimum tissue engraftment in the rat islet allotransplantation model. Lewis rat islets were cultured in TCM 199/5% fetal calf serum for 1 day at 37°C, followed by 1 day
Henning Jahr +3 more
doaj +1 more source

