Plasmodium vivax malaria elimination: should innovative ideas from the past be revisited?
Memorias do Instituto Oswaldo Cruz, 2014 In the 1950s, the strategy of adding chloroquine to food salt as a prophylaxis against malaria was considered to be a successful tool. However, with the development of Plasmodium resistance in the Brazilian Amazon, this control strategy was abandoned ...
Fernando Fonseca Val +6 more
doaj +1 more source
Rheumatology &Autoimmunity, EarlyView.Recent multi‐omics studies have demonstrated that belimumab specifically targets naïve B cells and a subset of memory B cells. This observation is consistent with belimumab's established efficacy and safety profile. Abstract Belimumab is an antibody targeting the cytokine B‐cell activating factor (BAFF), which is crucial for B cell differentiation, and
Keishi Fujio +5 more
wiley +1 more source
Nanomedicine Approaches for Autophagy Modulation in Cancer Therapy
Small Science, EarlyView.Autophagy modulation holds promise for enhancing cancer treatment, yet clinical translation remains challenging. This review explores nanomedicine‐based strategies to improve autophagy‐targeting drugs, highlighting their synergy with chemotherapy, immunotherapy, phototherapy, and gene therapy. It also discusses nanoparticle design and clinical progress,
Sohaib Mahri +11 more
wiley +1 more source
PROGUANIL—THE ISOLATION OF A METABOLITE WITH HIGH ANTIMALARIAL ACTIVITY [PDF]
, 1953 A. F. Crowther, A. A. Levi
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Global emergency medicine: A scoping review of the literature from 2023
Academic Emergency Medicine, Volume 32, Issue 5, Page 553-569, May 2025.Abstract Objective The Global Emergency Medicine Literature Review (GEMLR) highlights the highest‐quality research addressing emergency care in resource‐limited settings (ECRLS). This 18th edition reviews global emergency medicine (GEM) literature published during 2023.
Braden J. Hexom +76 more
wiley +1 more source
STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. I. METHOD FOR THE QUANTITATIVE ASSAY OF SUPPRESSIVE ANTIMALARIAL ACTION IN VIVAX MALARIA 123 [PDF]
, 1948 James A. Shannon +3 more
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Opportunities and Challenges of Population Pharmacogenomics
Annals of Human Genetics, EarlyView.ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou +3 more
wiley +1 more source
Antimalarial Activity and Toxicity of a Metabolic Derivative of Quinine [PDF]
, 1946 F. E. Kelsey +3 more
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Production and characterization of different types of malaria pigment (hemozoin) and their potential use for screening for hemozoin inhibiting drugs [PDF]
, 2012 Tese de mestrado. Biologia (Microbiologia Aplicada). Universidade de Lisboa, Faculdade de Ciências, 2012Malarial pigment, hemozoin, appears to modulate the immune system, however it remains controversial if it has stimulatory or inhibitory effects ...
Góis, Ana Margarida Ferreira, 1988-
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