Results 121 to 130 of about 63,797 (281)

Financial Toxicity Associated with Biological Medicines: A Scoping Review

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 81-93, July 2026.
Financial toxicity, defined as the economic burden experienced by patients due to medication and other healthcare costs and their consequences, such as material, psychosocial and behavioral effects, represents a significant concern for individuals receiving biological medicines.
Laura Sara Maria Saarukka, Kamilla Yamileva, Kari Linden, Anniina Simonen, Anna‐Riia Holmström   +4 more
wiley   +1 more source

Resistance to Antimalarials [PDF]

Journal of Tropical Pediatrics, 2002
openaire   +2 more sources

Advances in the Neurotoxic Mechanisms of Acrylamide and Multitarget Intervention Strategies of Natural Products

Food Frontiers, Volume 7, Issue 4, July 2026.
This review summarizes recent advances in acrylamide neurotoxicity mechanisms and highlights the multitarget neuroprotective effects of diverse natural products while also addressing current challenges and future translational research directions.
Wen Du, Yifan Zhao, Li Dong, Chen Ma, Xiaosong Hu, Daotong Li, Fang Chen, Yinghua Luo   +7 more
wiley   +1 more source

Population Pharmacokinetics and Pharmacodynamics of Paracetamol in Malaysian Patients With Plasmodium knowlesi Malaria

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 7, July 2026.
ABSTRACT Paracetamol may improve renal function in patients with severe Plasmodium knowlesi malaria, particularly in those with acute kidney injury and hemolysis, via inhibition of cell‐free hemoglobin mediated oxidative kidney damage. We developed a population pharmacokinetic/pharmacodynamic (PK/PD) model to assess effects of paracetamol on creatinine,
Thanaporn Wattanakul, Daniel J. Cooper, Katherine Plewes, Matthew J. Grigg, Giri S. Rajahram, Timothy William, Arjen M. Dondorp, Michael D. Edstein, Geoffrey W. Birrell, Nicholas M. Anstey, Richard M. Hoglund, Bridget E. Barber, Joel Tarning   +12 more
wiley   +1 more source

Gingival and Periodontal Diseases and Conditions in Children and Adolescents: Consensus Report

Journal of Clinical Periodontology, Volume 53, Issue 7, Page 1068-1099, July 2026.
ABSTRACT Background The objectives of this Focused Workshop were to update the epidemiology, aetiology, risk factors, diagnosis and management of gingival and periodontal diseases and conditions in children and adolescents, and to explore the applicability of the 2018 Classification in children and adolescents.
Iain Chapple, Sotiria Gizani, Mariano Sanz, Dominique Declerck, Phoebus Madianos, Valerie Clerehugh, Monique Danser, Esti Davidovich, Janet Davies, Nikos Donos, Elisabeth Dursun, Elena Figuero, Filippo Graziani, Mervi Gursoy, Soren Jepsen, Clara Joseph, Moritz Kebschull, Norbert Kraemer, Tina Lambrinaki, Rodrigo López, David J. Manton, Joerg Meyle, Ana Molina, Lior Shapira, Cheryl Somani, Georgios Tsilingaridis, Svante Twetman, Nicola West, Biniyam Wondimu, Ferranti Wong, David Herrera   +30 more
wiley   +1 more source

From the Proteome to Therapeutics: A Multi‐Database Approach to Drug Discovery in Periodontitis—An Exploratory Pilot Study

Journal of Clinical Periodontology, Volume 53, Issue 7, Page 990-1004, July 2026.
ABSTRACT Introduction This explanatory pilot study presents a workflow to identify approved drugs, which could be repurposed for periodontitis therapy using salivary proteomics combined with drug‐target database screening. Methods Proteomic analyses of saliva using LC–MS/MS were conducted in two independent settings: a cohort (sub‐study I, N = 187) and
Taisir Bozo, Annette Murr, Birte Holtfreter, Sebastian‐Edgar Baumeister, Peter Meisel, Uwe Völker, Werner Weitschies, Henry Völzke, Philipp Kanzow, Elke Hammer, Manuela Gesell Salazar, Thomas Kocher   +11 more
wiley   +1 more source

Unusual Palatal Pigmentation in a 71‐Year‐Old Patient

Oral Diseases, EarlyView.
Lucía Lago‐Méndez, Carlos Manuel de Neira de Paz, Pedro Diz‐Dios, Márcio Diniz‐Freitas   +3 more
wiley   +1 more source

Co(II), Cu(II), and Ni(II) Coordination Complexes: Synthesis, Characterization, Experimental, and Computational Study on Potential Antiplasmodial Activity

ChemMedChem, Volume 21, Issue 12, 26 June 2026.
Four isostructural complexes (C1–C4) derived from 2‐(tert‐butoxy)‐6‐(1H‐imidazol‐1‐yl)pyridine with axial halides exhibit octahedral trans M(L)4X2 geometries, confirmed by X‐ray diffraction. They feature a discrete 1,6M7−1 topology, identified using ToposPro analysis.
David Ezenarro‐Salcedo, Daniela Fonseca‐López, Alexander Patiño‐Cubides, María C. Velasco‐Pareja, María F. Yasnot‐Acosta, Camilo Serrano‐Sterling, Ana Rodríguez, Mario A. Macías, Adrian L. Orjuela, Augusto Valderrama‐Aguirre, John J. Hurtado   +10 more
wiley   +1 more source

1,1‐and 1,2‐Diborylalkenes: Preparation and Synthetic Applications

Advanced Synthesis &Catalysis, Volume 368, Issue 12, 17 June 2026.
In this review, we highlight recent advances in the synthesis and reactivity of 1,1‐diborylalkenes and 1,2‐diborylalkenes, along with various transformations leading to C‐C, C‐heteroatom, and multicomponent products. By providing a comprehensive and practical resource, this review aims to assist researchers in exploring the synthetic utility of 1,1 and
Jayaram Vankudoth, Maruti Mali, Fabienne Berrée   +2 more
wiley   +1 more source

Electron Donor–Acceptor Mediated Hydrosulfonylation of Olefins From N‐Hydroxymethylphthalimide Sulfones

Advanced Synthesis &Catalysis, Volume 368, Issue 12, 17 June 2026.
Electron donor–acceptor complex formation between tertiary amines and N‐hydroxymethylphthalimide sulfones enables photocatalyst‐free hydrosulfonylation of olefins through light‐induced sulfinyl radical generation. Sulfones are widely used sulfur‐VI motifs in pharmaceuticals.
Makayla L. Williams, Twinkle I. Patel, Matthew J. Moschitto   +2 more
wiley   +1 more source