Results 111 to 120 of about 28,999 (273)

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

A Cautionary Tale: The Risks of Unproven Antimalarials

A Cautionary Tale: The Risks of Unproven Antimalarials ...

core   +3 more sources

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Malaria prevention in travelling children

South African Family Practice, 2012
Preventing malaria in children is often neglected. Prevention is very important, as malaria is still a significant cause of childhood mortality. Parents must be aware that the same measures must be taken by children to avoid being bitten by mosquitoes ...
S. Mathijs
doaj   +1 more source

Quality of anti-malarial drugs provided by public and private healthcare providers in south-east Nigeria. [PDF]

, 2009
BACKGROUND: There is little existing knowledge about actual quality of drugs provided by different providers in Nigeria and in many sub-Saharan African countries.
Hanson, Kara, Dike Nkem, Paul Okonkwo, Shu Elvis, Harparkash Kaur, Onwujekwe, Obinna, Uzochukwu, Benjamin, Nkem Dike, Hanson Kara, Okoye Viola, Obinna Onwujekwe, Uzochukwu Benjamin, Viola Okoye, Kaur, Harparkash, Okoye, Viola, Benjamin Uzochukwu, Kara Hanson, Shu, Elvis, Elvis Shu, Kaur Harparkash, Dike, Nkem, Okonkwo, Paul, Onwujekwe Obinna, Okonkwo Paul   +23 more
core   +1 more source

Electrochemical aptasensors for ultrasensitive multiplexed detection: Towards a new era of precision diagnostics and environmental monitoring

VIEW, EarlyView.
Electrochemical aptasensors are emerging as powerful platforms for precision diagnostics and environmental monitoring, owing to their high selectivity, programmability and compatibility with miniaturised systems. However, their broader application is constrained by limited signal intensity and challenges in reliable multiplexed detection.
Azadeh Abdi, Ngoan Thi Thao Nguyen, Riccardo Zulli, Jacopo Giaretta, Fariba Dehghani, Syamak Farajikhah   +5 more
wiley   +1 more source

Use of antimalarials among participants who sought treatment for fever.

, 2015
Use of antimalarials among participants who sought treatment for fever.
Seeba Amenga Etego (828398), Livesy Naafoe Abokyi (828395), Emmanuel Mahama (324670), Kwaku Poku Asante (96320), Anthony Kwarteng (733299), Patricia Akweongo (488556), Jennifer Ayaam (828397), Abubakari Sulemana (828396), Bernhards Ogutu (683944), Stephaney Gyaase (337622), David Dosoo (223143), Seth Owusu-Agyei (80063), Dennis Adu-Gyasi (324667)   +12 more
core   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Expanding horizons for clinical applications of chloroquine, hydroxychloroquine, and related structural analogues

Drugs in Context, 2019
Several experimental and clinical studies have transformed the traditional antimalarial role of chloroquine (CHQ) and related structural analogues to potent therapeutic agents for a host of nonmalarial indications.
Ashutosh M Shukla, Aparna Wagle Shukla
doaj   +1 more source

Discoid Lupus Erythematosus in Genital Skin: A Case Report and Review of the Literature

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Discoid lupus erythematosus (DLE) represents the most common variant of chronic cutaneous lupus erythematosus, a skin‐specific autoimmune disorder within the broader lupus erythematosus spectrum Clinically, DLE is characterized by erythematous, scaly plaques with areas of hyperpigmentation.
Ala' Abu‐Dayeh, Daniel Miller, Alessio Giubellino   +2 more
wiley   +1 more source