Results 161 to 170 of about 51,125 (324)

Mefloquine Suppresses Metastasis in Renal Cell Carcinoma Through Targeting SPC25

Cancer Science, Volume 116, Issue 5, Page 1239-1254, May 2025.
We addressed the clinical issue of renal cell carcinoma metastasis by identifying SPC25 protein as a research target through bioinformatics techniques and validation with clinical samples. We comprehensively validated the function of SPC25 protein and determined its impact on renal cancer.
Yongbo Wang, He Wang, Yipeng Xu, Jiawei Ling, Chuhong Zong, Yan Zhang, Xiaoxuan Guo, Guanan Zhao, Yuan Zhou, Jiahui Zhao, Pengrong Lou, Xigao Liu, Tengfei Xu, Qi Ma   +13 more
wiley   +1 more source

Superiority of "Camoquin" Over Other Antimalarials [PDF]

, 1952
Ishwar Singh, T. S. Kalyanum
openalex   +1 more source

Visions of Community Health and the Social Good in Kenya: Turning Community Health Workers into Entrepreneurs

Development and Change, EarlyView.
ABSTRACT In East Africa, social enterprises that fuse development work with entrepreneurial activities and a language of ‘innovation’ are becoming prominent. Critical of the NGO/donor model, which they hold as unsustainable, such organizations are funded by corporate investment and philanthropic capital but aim for self‐reliance through enlisting local
Edwin Ambani Ameso, Ruth Jane Prince
wiley   +1 more source

THE GLUCOSE METABOLISM OF PLASMODIUM GALLINACEUM, AND THE ACTION OF ANTIMALARIAL AGENTS [PDF]

, 1948
P. B. MARSHALL
openalex   +1 more source

Novel antimalarial targets and the antimalarial pipeline [PDF]

International Journal of Infectious Diseases, 2014
openaire   +3 more sources

A general language model for peptide identification [PDF]

arXiv
Advances in peptide identification are revolutionizing our ability to decipher protein functions and accelerate therapeutic discovery. We present PDeepPP, a deep learning framework that integrates pretrained protein language models with parallel transformer-CNN architectures, achieving state-of-the-art performance in peptide characterization tasks. The
arxiv  

Structure–activity analysis of imino‐pyrimidinone‐fused pyrrolidines aids the development of dual plasmepsin V and plasmepsin X inhibitors

The FEBS Journal, EarlyView.
Compounds were identified that inhibit the aspartic protease plasmepsin V from Plasmodium vivax. Further development of these compounds identified compounds, such as S‐WM48, that could inhibit both plasmepsin V and plasmepsin X but plasmepsin IX was not significantly inhibited.
Anthony N. Hodder, Brad E. Sleebs, Greg Adams, Sina Rezazadeh, Anna Ngo, Kate Jarman, Stephen Scally, Peter Czabotar, Hongwu Wang, John A. McCauley, David B. Olsen, Alan F. Cowman   +11 more
wiley   +1 more source

ACRIDINE DERIVATIVES AS ANTIMALARIALS. PART ll [PDF]

, 1939
U. P. BASU, S. J. DAS-GUPTA
openalex   +1 more source

d‐amino acids: new functional insights

The FEBS Journal, EarlyView.
This review explores recent advances in understanding d‐amino acids (d‐AAs) and their pivotal roles across organisms, from plants to humans. d‐AAs have been implicated in key physiological processes, including cancer, inflammation, immune regulation, kidney disease, diabetes, and nervous system function.
Loredano Pollegioni, Natasa Kustrimovic, Luciano Piubelli, Elena Rosini, Valentina Rabattoni, Silvia Sacchi   +5 more
wiley   +1 more source

The Diagnostic Performance of a Sysmex XN‐31 Automated Malaria Analyzer vs. Expert Microscopy

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Malaria is a common and life‐threatening infection. Malaria diagnosis needs to be fast and reliable. Although malaria microscopy is currently the gold standard, it is laborious, requires extensive training, and relies heavily on the proficiency of microscopists.
S. Onsongo, K. Otieno, L. Mathenge, E. Makotsi, G. Kariuki, V. Ngetich, G. Muriithi, A. T. Harrison, T. Odawo, S. Kariuki   +9 more
wiley   +1 more source