Results 161 to 170 of about 91,276 (376)
Plant-derived antimalarial agents: from crude extracts to isolated bioactive compounds [PDF]
, 2011 Despite decades of intense research, malaria remains a deadly disease of the developing worlds. Drugresistance to limited available antimalarials, in part, has contributed to the persistence of this infectious disease.
Abdullah, Wan Omar, Ismail, Patimah
core
The FEBS Journal, EarlyView.Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk +8 more
wiley +1 more source
Editorial: Frontiers in malaria research
Frontiers in Microbiology, 2023 Ritu Gill +5 more
doaj +1 more source
ACRIDINE DERIVATIVES AS ANTIMALARIALS. PART ll [PDF]
, 1939 U. P. BASU, S. J. DAS-GUPTA
openalex +1 more source
Novel antimalarial targets and the antimalarial pipeline [PDF]
International Journal of Infectious Diseases, 2014 openaire +3 more sources
The FEBS Journal, EarlyView.Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner +13 more
wiley +1 more source
A Prospective Analysis of Adverse Drug Reactions in a South Indian Hospital [PDF]
, 2009 Adverse drug reactions are a great cause of concern to the medical profession, the patients and the pharmaceutical industry. However ADR reporting and monitoring is yet to catch up in India.
Adhikari, P, Padmaja, U, Pereira, P
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Effectiveness of Antimalarial Drugs
New England Journal of Medicine, 2005 A global resurgence of malaria has taken place as a result of a lapse in preventive efforts and the emergence of resistance to standard antimalarial drugs. New therapies are available, but because of social, economic, and clinical factors, the use of older drugs persists.
openaire +4 more sources
Highly divergent apicomplexan cytoskeletons provide additional models for actin biology
The FEBS Journal, EarlyView.Actin is a highly conserved, abundant and central molecule in eukaryotes. Apicomplexans contain some of the most sequence‐divergent actin cytoskeletons known. This divergence results in overlapping yet different biochemical properties. Here, we highlight the remarkable divergence of the actin cytoskeleton by comparing apicomplexan to classical systems,
Yukino Kobayashi, Ross G. Douglas
wiley +1 more source