Results 11 to 20 of about 91,276 (376)
Marine Drugs, 2009 Malaria is an infectious disease causing at least 1 million deaths per year, and, unfortunately, the chemical entities available to treat malaria are still too limited.
Orazio Taglialatela-Scafati +1 more
doaj +4 more sources
On peroxide antimalarials [PDF]
Journal of the Serbian Chemical Society, 2007 Several dicyclohexylidene tetraoxanes were prepared in order to gain a further insight into structure-activity relationship of this kind of antimalarials.
Opsenica Igor +6 more
doaj +5 more sources
Tackling resistance: Emerging antimalarials and new parasite targets in the era of elimination [version 1; referees: 2 approved] [PDF]
F1000Research, 2018 Malaria remains a significant contributor to global human mortality, and roughly half the world’s population is at risk for infection with Plasmodium spp. parasites.
Matthews, Emily S, Odom John, Audrey R
core +3 more sources
Arthritis & Rheumatology, 2022 The pathogenesis of cutaneous lupus erythematosus (CLE) is multifactorial, and CLE is difficult to treat due to the heterogeneity of inflammatory processes among patients.
J. Patel +12 more
semanticscholar +1 more source
Acridine-Based Antimalarials—From the Very First Synthetic Antimalarial to Recent Developments
Molecules, 2021 Malaria is among the deadliest infectious diseases in the world caused by Plasmodium parasites. Due to the high complexity of the parasite’s life cycle, we partly depend on antimalarial drugs to fight this disease.
Mélanie Fonte +3 more
semanticscholar +1 more source
Quinoline Antimalarials Increase the Antibacterial Activity of Ampicillin
Frontiers in Microbiology, 2021 Bacterial and malaria co-infections are common in malaria endemic countries and thus necessitate co-administration of antibiotics and antimalarials. There have long been anecdotal clinical reports of interactions between penicillins and antimalarial ...
O. Olateju +6 more
semanticscholar +1 more source
Hydroxychloroquine and Antimalarials [PDF]
The Journal of Rheumatology, 2019 We read the editorial by Sandhu, et al1 about antimalarial-induced cardiomyopathy in systemic lupus erythematosus2, and we want to point out some inaccuracies in the brief review of the history of antimalarials that they presented.
LUIS CAMINAL-MONTERO +1 more
openaire +3 more sources
Journal of the Serbian Chemical Society, 2009 The problem of endemic malaria continues unabated globally. Malaria affects 40 % of the global population, causing an estimated annual mortality of 1.5-2.7 million people. The World Health Organization (WHO) estimates that 90 % of these deaths occur in sub-Saharan Africa among infants under the age of five.
Dejan Opsenica, Bogdan Solaja
openaire +4 more sources
Biomolecules, 2020 Chemotherapy plays a key role in breast cancer therapy, but drug resistance and unwanted side effects make the treatment less effective. We propose a new combination model that combines antineoplastic drugs and antimalarials for breast cancer therapy ...
Diana Duarte, N. Vale
semanticscholar +1 more source
Frontiers in Drug Safety and Regulation, 2023 Introduction: The antimalarials chloroquine and hydroxychloroquine have been used for several decades in treating malaria and some autoimmune diseases—mainly rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)—with excellent efficacy and ...
Pedro Santos-Moreno +8 more
doaj +1 more source