Results 21 to 30 of about 38,148 (251)

Focusing on quality patient care in the new global subsidy for malaria medicines. [PDF]

open access: yes, 2009
Tido von Schoen-Angerer and colleagues discuss the new Affordable Medicines Facility for malaria (AMFm), which subsidizes and facilitates access to artemisinin-based combination therapy, and what mechanisms are needed to ensure it stays focused on ...
Moon, S   +4 more
core   +2 more sources

Susceptibilidad in vitro de aislamientos colombianos de Plasmodium falciparum a diferentes antipalúdicos

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2008
Introducción. Los estudios de susceptibilidad in vitro de Plasmodium falciparum a los medicamentos antipalúdicos son herramientas importantes para vigilar la utilidad de esos medicamentos; tales estudios son escasos en Colombia. Objetivo.
Silvia Blair   +2 more
doaj   +1 more source

Targeting proteases and proteolytic processing of unusual N-terminal extensions of Plasmodium proteins: parasite peculiarity

open access: yesFrontiers in Drug Discovery, 2023
More than sesquicentennial years of malarial research, however the unique malarial parasite, Plasmodium still bewilders us with its atypical characteristic features.
Ankita Tehlan   +3 more
doaj   +1 more source

Genetic and genomic approaches for the discovery of parasite genes involved in antimalarial drug resistance [PDF]

open access: yes, 2013
The biggest threat to the war on malaria is the continued evolution of drug resistance by the parasite. Resistance to almost all currently available antimalarials now exists in Plasmodium falciparum which causes the most suffering among all human malaria
Mwangi, J.M., Ranford-Cartwright, L.C.
core   +1 more source

Malaria: The Past and the Present

open access: yesMicroorganisms, 2019
Malaria is a severe disease caused by parasites of the genus Plasmodium, which is transmitted to humans by a bite of an infected female mosquito of the species Anopheles.
Jasminka Talapko   +4 more
doaj   +1 more source

In vitro synergy and enhanced murine brain penetration of saquinavir coadministered with mefloquine. [PDF]

open access: yes, 2005
Highly active antiretroviral therapy has substantially improved prognosis in human immunodeficiency virus (HIV). However, the integration of proviral DNA, development of viral resistance, and lack of permeability of drugs into sanctuary sites (e.g ...
Back, DJ   +9 more
core   +1 more source

Knowledge of Malaria and Its Uncomplicated Treatment with Argemone mexicana L. in Selected Districts of Jimma Zone, Oromia Regional State, Ethiopia: A Community-Based Cross Sectional Survey

open access: yesInfection and Drug Resistance, 2022
Tamirat Tekassa,1 Gemmechu Hasen,1 Hailu Merga,2 Anne-Laure Cavin,3 Bertrand Graz,3 Sultan Suleman1 1School of Pharmacy, Institute of Health, Jimma University, Jimma, Oromia Regional State, Ethiopia; 2Department of Epidemiology, Institute of Health ...
Tekassa T   +5 more
doaj  

Adherence to a Six-Dose Regimen of Artemether-Lumefantrine for Treatment of Uncomplicated Plasmodium Falciparum Malaria in Uganda. [PDF]

open access: yes, 2004
Measuring baseline levels of adherence and identifying risk factors for non-adherence are important steps before the introduction of new antimalarials. In Mbarara in southwestern Uganda, we assessed adherence to artemether-lumefantrine (Coartem) in its ...
Bajunirwe, F   +9 more
core   +2 more sources

Impact of Drug Pressure versus Limited Access to Drug in Malaria Control: The Dilemma

open access: yesMedicines, 2022
Malaria burden has severe impact on the world. Several arsenals, including the use of antimalarials, are in place to curb the malaria burden. However, the application of these antimalarials has two extremes, limited access to drug and drug pressure ...
Chinedu Ogbonnia Egwu   +6 more
doaj   +1 more source

The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin. [PDF]

open access: yes, 2002
Trypanosoma cruzi glutathione-dependent peroxidase I (TcGPXI) can reduce fatty acid, phospholipid, and short chain organic hydroperoxides utilizing a novel redox cycle in which enzyme activity is linked to the reduction of trypanothione, a parasite ...
Docampo   +56 more
core   +3 more sources

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