Results 41 to 50 of about 26,961 (258)

Hydroxychloroquine‐induced erythema multiforme

Clinical Case Reports, 2020
Hydroxychloroquine is a commonly used medication and rarely may result in development of erythema multiforme. This potential cutaneous side effect should be highlighted in information given to patients prior to hydroxychloroquine commencement.
Dimitra Koumaki, Vasiliki Koumaki, George Bertsias, Sotirios Boumpoucheropoulos, Alexander Katoulis, Maria Stefanidou, Orestis Miaris, George Evangelou, Kyriaki Zografaki, Sabine Elke Krueger‐Krasagakis, Konstantinos Krasagakis   +10 more
doaj   +1 more source

Antimalarials: Pre-Clinical development update [PDF]

, 2017
Diverse strategies exist for the development of novel antimalarials drug to tackle the increasing incidence of artemisin resistance. New molecules have been developed which hold a promise to cater to this unmet need.
Koustuv Chowdhury, Rajasree Sinha, Sandeep Lahiry, Shouvik Choudhury, Moumita Bala, Ayan Mukherjee, Prajesh Kiran Bhunya   +6 more
core   +1 more source

Blood schizontocidal activity of methylene blue in combination with antimalarials against Plasmodium falciparum

Parasite, 2007
Methylene blue (MB) is the oldest synthetic antimalarial. It is not used anymore as antimalarial but should be reconsidered. For this purpose we have measured its impact on both chloroquine sensitive and resistant Plasmodium strains.
Garavito G., Bertani S., Rincon J., Maurel S., Monje M.C., Landau I., Valentin A., Deharo E.   +7 more
doaj   +1 more source

In vitro drug interaction of ionophores with artemisinin and chloroquine against Plasmodium falciparum 3D7 blood-stage infection

Frontiers in Drug Discovery, 2023
The prevalence of clinical resistance of P. falciparum towards artemisinin and its partner drugs has significantly hampered malarial chemotherapy. To circumvent this situation, identifying a new class of partner drugs with significant anti-malarial ...
Vinoth Rajendran, Keerthana Gurukkalot
doaj   +1 more source

Discovery and development of 2-aminobenzimidazoles as potent antimalarials. [PDF]

, 2021
The emergence of Plasmodium falciparum resistance to frontline antimalarials, including artemisinin combination therapies, highlights the need for new molecules that act via novel mechanisms of action.
De Paoli, Amanda, Scammells, Peter J, Creek, Darren J, Devine, Shane M, Challis, Matthew P, Siddiqui, Ghizal, Kigotho, Jomo K, Norton, Raymond S, MacRaild, Christopher A, Avery, Vicky M   +9 more
core   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Mucocutaneous Disease Activity and Damage Accrual in Systemic Lupus Erythematosus: Analyses From the Asia‐Pacific Lupus Collaboration Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective This research article aims to describe the prevalence, associations, and health‐related quality of life (HRQoL) impact of mucocutaneous features of systemic lupus erythematosus (SLE). Methods Data from the Asia‐Pacific Lupus Collaboration cohort were analyzed (2013–2021).
Amanda M. Saracino, Yanjie Hao, Dylan Hansen, Yi‐Hsing Chen, Alberta Hoi, Vera Golder, Jiacai Cho, Aisha Lateef, Worawit Louthrenoo, Laniyati Hamijoyo, Shue Fen Luo, Yeong‐Jian Jan Wu, Sandra Navarra, Leonid Zamora, Chak Sing Lau, Shirley Chan, Zhanguo Li, Hai‐hong Yao, Sargunan Sockalingam, B. M. D. B. Basnayake, Yasuhiro Katsumata, Masayoshi Harigai, Zhuoli Zhang, Jun Kikuchi, Yuko Kaneko, Tsutomu Takeuchi, Madelynn Chan, Sang‐Cheol Bae, Fiona Goldblatt, Sean O'Neill, Geraldine Hassett, Kristine Ng, Nicola Tugnet, Mark Sapsford, Yih Jia Poh, Michael Tee, Cherica Tee, Naoaki Ohkubo, Yoshiya Tanaka, Rangi Kandane‐Rathnayake, Eric Morand, Shereen Oon, Mandana Nikpour   +42 more
wiley   +1 more source

Antimalarials and the eye [PDF]

, 1989
Following the first reports in 1954 of the beneficial effects of chloroquine in cases of lupus erythematosus, this drug and its numerous derivatives have been used extensively in the treatment of systemic and discoid lupus erythematosus and rheumatoid ...
Coleiro, Joseph A.
core  

Attempts to Prepare Antimalarials. Part IV. Derivatives of Cotarnine. [PDF]

, 1933
Attempts to Prepare Antimalarials. Part IV.
GURCHARAN SINGH AHLUWALIA, JNANENDRA NATH RÂY, KANSHI NATH KAUL   +2 more
core   +1 more source

Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activity [PDF]

, 2021
Malaria is a devastating disease caused by Plasmodium parasites. Emerging resistance against current antimalarial therapeutics has engendered the need to develop antimalarials with novel structural classes.
Wilson, D.W., Boddey, J.A., Lowes, KN, Parkyn Schneider, M., Avery, V.M., Duffy, S., Ashton, T.D., Gilson, P.R., Romeo, O., Sabroux, H.J., Bullen, H.E., Sabroux, HJ, Nguyen, N., Parkyn Schneider, M, Duffy, S, Boddey, JA, Cowman, A.F., Ashton, TD, Bullen, HE, Nguyen, N, Wilson, DW, Steel, RWJ, Avery, VM, Favuzza, P, Ngo, A., Gancheva, M.R., Ngo, A, Steel, R.W.J., Lowes, K.N., Sleebs, B.E., Romeo, O, Gancheva, MR, Favuzza, P., et al.   +33 more
core   +1 more source