Results 41 to 50 of about 29,390 (250)

Clinical Characteristics and Management of Patients With Clinical Amyopathic Dermatomyositis: A Retrospective Study of 64 Patients at a Tertiary Dermatology Department

Frontiers in Medicine, 2021
Background: Clinical amyopathic dermatomyositis (CADM) represents a subtype of 5–20% of patients with dermatomyositis (DM), which can be categorized into amyopathic dermatomyositis (ADM) and hypomyopathic dermatomyositis (HDM).
Keyun Tang, Hanlin Zhang, Hongzhong Jin
doaj   +1 more source

The Interplay Between Molybdopterin Synthase and Metal Metabolism Contributes to Pathogenicity in Acinetobacter baumannii

Advanced Science, EarlyView.
Pathogenic Acinetobacter baumannii scavenges metal ions as nutritional elements to survive within the host. This study demonstrates that molybdopterin synthase is essential for pathogenesis and full virulence during infection. Molybdopterin synthase subunit MoaE constitutes an intrinsically disordered C‐terminal histidine rich tail, which mediates ...
Min Jiao, Wenbo He, Zhenlin Ouyang, Ruochen Wang, Jiaxin Zhang, Xin Liu, Yiting Jing, Qinyue Yu, Xiaoyu He, Qian Qin, Litao Guo, Peter M. Hwang, Fang Zheng, Yurong Wen   +13 more
wiley   +1 more source

Optimization of 2,3-Dihydroquinazolinone-3-carboxamides as Antimalarials Targeting PfATP4

, 2023
Optimization of 2,3-Dihydroquinazolinone-3-carboxamides as Antimalarials Targeting ...
DA Fidock (14529620), X Zhang (6084905), B Chandra Maity (19861182), TD Ashton (14467038), T Yeo (13371246), KE Jarman (19453840), A Churchyard (10042406), AF Cowman (14467050), MG Dans (14461737), D Qiu (13534753), J Baum (13685923), KN Lowes (14461743), BE Sleebs (14461755), S Brand (7776398), AM Lehane (15822026), AC Uhlemann (14527571), A Ngo (9854420), KA Schindler (22234438), PF Jackson (19453858), D Baud (17409018), P Favuzza (13410966), H Park (7811786), N De (19561534)   +22 more
core  

Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria

American Journal of Hematology, EarlyView.
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho, Hasrini Rini, Noy N. Kambuaya, Syawal Satria, Freis Candrawati, Putu A. I. Shanti, King Alexander, Benediktus Andries, Aisah R. Amelia, Anjana Rai, Kim A. Piera, Agatha M. Puspitasari, Ristya Amalia, Pak Prayoga, Leo Leonardo, Maulina Hafidzah, Theo Situmorang, Dewi S. Margayani, Desandra A. Rahmayenti, Pengxing Cao, Enny Kenangalem, Leily Trianty, Damian Oyong, Julie A. Simpson, Rintis Noviyanti, Pierre A. Buffet, Jeanne R. Poespoprodjo, Nicholas M. Anstey   +27 more
wiley   +1 more source

Attempts to Prepare Antimalarials. Part IV. Derivatives of Cotarnine.

, 1933
Attempts to Prepare Antimalarials. Part IV.
GURCHARAN SINGH AHLUWALIA, JNANENDRA NATH RÂY, KANSHI NATH KAUL   +2 more
core   +1 more source

Human pharmacokinetics of antimalarials tested in this study.

, 2013
Human pharmacokinetics of antimalarials tested in this study.
Ingmar Peitz (503779), R. Kiplin Guy (160393), Margaret A. Phillips (270292), Richard K. Haynes (450226), Jonathan L. Vennerstrom (503780), Kelly Chibale (503778), Rob Hooft van Huijsduijnen (151694), Gerhard Kelter (78338), Timothy N. C. Wells (422572), Yongyuth Yuthavong (269209)   +9 more
core   +1 more source

Increased Risk of Intrahepatic Cholestasis of Pregnancy in Women With Systemic Lupus Erythematosus Exposed to Azathioprine

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the risk of intrahepatic cholestasis of pregnancy (ICP) in azathioprine (AZA)–exposed versus unexposed systemic lupus erythematosus (SLE) pregnancies within the multicenter prospective Lupus in Pregnancy (LEGACY) cohort. Methods LEGACY is conducted at Systemic Lupus International Collaborating Clinics in Canada, South Korea, Peru,
Reem Farhat, Maria del Carmen Zamora‐Medina, Sang‐Cheol Bae, Megan R. W. Barber, Ann E. Clarke, Paul R. Fortin, Zahi Touma, Carl A. Laskin, Isabelle Malhamé, Giada Sebastiani, Christine Peschken, Manuel F. Ugarte‐Gil, Alexandra Legge, Sasha Bernatsky, Évelyne Vinet   +14 more
wiley   +1 more source

A Cautionary Tale: The Risks of Unproven Antimalarials

A Cautionary Tale: The Risks of Unproven Antimalarials ...

core   +3 more sources

Plasmodium vivax malaria elimination: should innovative ideas from the past be revisited?

Memorias do Instituto Oswaldo Cruz, 2014
In the 1950s, the strategy of adding chloroquine to food salt as a prophylaxis against malaria was considered to be a successful tool. However, with the development of Plasmodium resistance in the Brazilian Amazon, this control strategy was abandoned ...
Fernando Fonseca Val, Vanderson Souza Sampaio, Maria Belén Cassera, Raquel Tapajós Andrade, Pedro Luiz Tauil, Wuelton Marcelo Monteiro, Marcus Vinícius Guimarães Lacerda   +6 more
doaj   +1 more source

Peripheral Blood DNA Methylation Changes Precede Lymphoma Diagnosis in Primary Sjögren's Disease

Arthritis &Rheumatology, EarlyView.
Objective Primary Sjögren's disease (SjD) is a systemic autoimmune disease associated with an increased risk of lymphoma. The molecular mechanisms underlying lymphomagenesis remain poorly understood, and sensitive biomarkers for early identification of patients at high risk of developing lymphoma are lacking.
Hanna Lidberg, Cecilia Fugmann, Juliana Imgenberg‐Kreuz   +2 more
wiley   +1 more source