Results 51 to 60 of about 26,961 (258)
Frontiers in Pharmacology, 2023 Due to the outbreak of the SARS-CoV-2 virus, drug repurposing and Emergency Use Authorization have been proposed to treat the coronavirus disease 2019 (COVID-19) during the pandemic. While the efficiency of the drugs has been discussed, it was identified
Seung-Hyun Yoon +6 more
doaj +1 more source
Antiretrovirals as Antimalarial Agents [PDF]
The Journal of Infectious Diseases, 2004 Recent studies have indicated that antiretroviral protease inhibitors may affect outcome in malarial disease. We have investigated the antimalarial activities of 6 commonly used antiretroviral agents. Our data indicate that, in addition to the previously published effects on cytoadherence and phagocytosis, the human immunodeficiency virus (HIV)-1 ...
S. Skinner-Adams, Tina +4 more
openaire +5 more sources
Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus
Arthritis Care &Research, EarlyView.Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai +7 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Objective Systemic lupus erythematosus (SLE) significantly impacts employment capacity. This study aimed to investigate the impact of burden of disease activity, damage, and treatment on employment outcomes and transitions in patients with SLE. Materials and Methods Using data from a single center, we analyzed employment transitions, adjusted mean ...
Javier Mencia‐Ledo +4 more
wiley +1 more source
Endoperoxide antimalarials: development, structural diversity and pharmacodynamic aspects with reference to 1,2,4-trioxane-based structural scaffold [PDF]
, 2016 Mithun Rudrapal, Dipak Chetia Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, India Abstract: Malaria disease continues to be a major health problem worldwide due to the emergence of multidrug-resistant strains of Plasmodium ...
Chetia D, Rudrapal M
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Human pharmacokinetics of antimalarials tested in this study. [PDF]
, 2013 Human pharmacokinetics of antimalarials tested in this study.
Ingmar Peitz (503779) +9 more
core +1 more source
Malaria prevention in travelling children
South African Family Practice, 2012 Preventing malaria in children is often neglected. Prevention is very important, as malaria is still a significant cause of childhood mortality. Parents must be aware that the same measures must be taken by children to avoid being bitten by mosquitoes ...
S. Mathijs
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang +7 more
wiley +1 more source
Photocatalytic Synthesis of Pentafluorosulfanyl Ketones, Acetals, and BCP Motifs Utilizing SF6
Advanced Science, EarlyView.A photocatalytic single electron reduction strategy is reported for the activation and valorization of sulfur hexafluoride (SF6), a potent greenhouse gas. Under mild conditions, SF6 is reduced to generate pentafluorosulfanyl (SF5) radicals, enabling direct access to pentafluorosulfanyl ketones, acetals, and BCP motifs.
Chen‐Hui Jiang +11 more
wiley +1 more source
A Review of Quinolone Antimalarials [PDF]
, 2020 Malaria affects millions of people worldwide. Resistance to drugs that treat malaria has increased the demand for efficient drugs. The search for antimalarial drugs has led to the synthesis of a vast number of quinolone analogues as potential ...
Velazquez, Miriam
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