Results 21 to 30 of about 33,834 (203)

Comparison of Health Service Utilization for Febrile Children Before and After Introduction of Malaria Rapid Diagnostic Tests and Artemisinin-Based Combination Therapy in Rural Papua New Guinea

Frontiers in Public Health, 2018
BackgroundIn Papua New Guinea (PNG), a malaria treatment policy using rapid diagnostic tests (RDTs) plus artemisinin-based combination therapy (ACT) was widely introduced to rural communities in 2012.
Takahiro Tsukahara, Takahiro Tsukahara, Takuma Sugahara, Takuro Furusawa, Francis Wanak Hombhanje   +4 more
doaj   +1 more source

New 4-aminoquinolines as moderate inhibitors of P. falciparum malaria [PDF]

Journal of the Serbian Chemical Society, 2021
Synthesis of novel aminoquinoline derivatives has been accomplished and their activity against malaria strains has been examined. The compounds showed moderate in vitro antimalarial activity against two P.
Opsenica Igor, Selaković Milica, Tot Mikloš, Verbić Tatjana, Srbljanović Jelena, Štajner Tijana, Đurković-Đaković Olgica, Šolaja Bogdan   +7 more
doaj   +1 more source

Differential effects of clinically used derivatives and metabolites of artemisinin in the activation of constitutive androstane receptor isoforms [PDF]

, 2012
BACKGROUND AND PURPOSE Widespread resistance to antimalarial drugs requires combination therapies with increasing risk of pharmacokinetic drugdrug interactions.
Alexander, Arnold, Asimus, Auerbach, Auerbach, Baes, Berman, Blättler, Burk, Burk, di Masi, Dring, Elsherbiny, Faucette, Gautam, Giao, Grace, Halgren, Hesse, Hoffart, Honda, Huey, Hustert, Jyrkkärinne, Kawamoto, Kerb, Khoo, Krey, Kyle, Lee, Maglich, Moore, Morris, Navaratnam, Nussler, Pan, Pissios, Ross, Sanner, Simonsson, Skinner-Adams, Svensson, Svärd, Wang, Ward, White, WHO, WHO, Windshügel, Wolbold, Xu, Zhang   +51 more
core   +1 more source

Susceptibilidad in vitro de aislamientos colombianos de Plasmodium falciparum a diferentes antipalúdicos

Biomédica: revista del Instituto Nacional de Salud, 2008
Introducción. Los estudios de susceptibilidad in vitro de Plasmodium falciparum a los medicamentos antipalúdicos son herramientas importantes para vigilar la utilidad de esos medicamentos; tales estudios son escasos en Colombia. Objetivo.
Silvia Blair, Eliana Arango, Jaime Carmona Fonseca   +2 more
doaj   +1 more source

The Rare, the Best: Spread of Antimalarial-Resistant Plasmodium falciparum Parasites by Anopheles Mosquito Vectors

Microbiology Spectrum, 2021
The emergence of resistance to antimalarials has prompted the steady switch to novel therapies for decades. Withdrawal of antimalarials, such as chloroquine in sub-Saharan Africa in the late 1990s, led to rapid declines in the prevalence of resistance ...
Antoine Berry, Sandie Menard, Sandrine E. Nsango, Luc Abate, Didier Concordet, Majoline Tchioffo Tsapi, Xavier Iriart, Parfait H. Awono-Ambéné, Benjamin Roche, Isabelle Morlais   +9 more
doaj   +1 more source

Comparative analysis of two methods for measuring sales volumes during malaria medicine outlet surveys. [PDF]

, 2013
BACKGROUND: There is increased interest in using commercial providers for improving access to quality malaria treatment. Understanding their current role is an essential first step, notably in terms of the volume of diagnostics and anti-malarials they ...
Goodman, Catherine, Hanson, Kara, Kleinschmidt, Immo, O'Connell, Kate, Palafox, Benjamin, Patouillard, Edith, Pok, Sochea, Tougher, Sarah   +7 more
core   +2 more sources

Malaria: The Past and the Present

Microorganisms, 2019
Malaria is a severe disease caused by parasites of the genus Plasmodium, which is transmitted to humans by a bite of an infected female mosquito of the species Anopheles.
Jasminka Talapko, Ivana Škrlec, Tamara Alebić, Melita Jukić, Aleksandar Včev   +4 more
doaj   +1 more source

The COVID-19 Treatment Landscape: A South African Perspective on a Race Against Time

Frontiers in Medicine, 2021
The pandemic caused by SARS-CoV-2 has infected more than 94 million people worldwide (as of 17 January 2020). Severe disease is believed to be secondary to the cytokine release syndrome (CRS or “cytokine storm”) which causes local tissue damage as well ...
Candice Laverne Hendricks, Candice Herd, Marcel Nel, Gregory Tintinger, Michael Sean Pepper   +4 more
doaj   +1 more source

Polymeric Nanocarriers for the Delivery of Antimalarials

Molecules, 2018
Malaria is an infectious disease caused by a protozoan parasite which is transmitted by female Anopheles mosquitoes around tropical and sub-tropical regions. Half of the world’s population is at risk of being infected by malaria.
Zandile Mhlwatika, Blessing Atim Aderibigbe   +1 more
doaj   +1 more source

The Knockout for G Protein-Coupled Receptor-Like PfSR25 Increases the Susceptibility of Malaria Parasites to the Antimalarials Lumefantrine and Piperaquine but Not to Medicine for Malaria Venture Compounds

Frontiers in Microbiology, 2021
Previously we have reported that the G protein-coupled receptor (GPCR)-like PfSR25 in Plasmodium falciparum is a potassium (K+) sensor linked to intracellular calcium signaling and that knockout parasites (PfSR25-) are more susceptible to oxidative ...
Benedito M. Santos, Bárbara K. M. Dias, Myna Nakabashi, Celia R. S. Garcia   +3 more
doaj   +1 more source