Results 51 to 60 of about 51,125 (324)
Genetic and genomic approaches for the discovery of parasite genes involved in antimalarial drug resistance [PDF]
, 2013 The biggest threat to the war on malaria is the continued evolution of drug resistance by the parasite. Resistance to almost all currently available antimalarials now exists in Plasmodium falciparum which causes the most suffering among all human malaria
Mwangi, J.M., Ranford-Cartwright, L.C.
core +1 more source
Antiplasmodial activity of p-substituted benzyl thiazinoquinone derivatives and their potential against parasitic infections [PDF]
, 2020 Malaria is a life-threatening disease and, what is more, the resistance to available antimalarial drugs is a recurring problem. The resistance of Plasmodium falciparum malaria parasites to previous generations of medicines has undermined malaria control ...
Basilico, Nicoletta +6 more
core +1 more source
Parasite, 2007 Methylene blue (MB) is the oldest synthetic antimalarial. It is not used anymore as antimalarial but should be reconsidered. For this purpose we have measured its impact on both chloroquine sensitive and resistant Plasmodium strains.
Garavito G. +7 more
doaj +1 more source
End-to-end Malaria Diagnosis and 3D Cell Rendering with Deep Learning [PDF]
arXiv, 2021 Malaria is a parasitic infection that poses a significant burden on global health. It kills one child every 30 seconds and over one million people annually. If diagnosed in a timely manner, however, most people can be effectively treated with antimalarial therapy. Several deaths due to malaria are byproducts of disparities in the social determinants of
arxiv
Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials. [PDF]
, 2008 BACKGROUND: Artemisinin combination therapies (ACT), which are increasingly being introduced for treatment of Plasmodium falciparum malaria, are more effective against sexual stage parasites (gametocytes) than previous first-line antimalarials and ...
Bousema, Teun +4 more
core +3 more sources
Hydroxychloroquine‐induced erythema multiforme
Clinical Case Reports, 2020 Hydroxychloroquine is a commonly used medication and rarely may result in development of erythema multiforme. This potential cutaneous side effect should be highlighted in information given to patients prior to hydroxychloroquine commencement.
Dimitra Koumaki +10 more
doaj +1 more source
Diamond magnetic microscopy of malarial hemozoin nanocrystals [PDF]
Phys. Rev. Applied 11, 034029 (2019), 2018 Magnetic microscopy of malarial hemozoin nanocrystals was performed using optically detected magnetic resonance imaging of near-surface diamond nitrogen-vacancy centers. Hemozoin crystals were extracted from $Plasmodium$-$falciparum$-infected human blood cells and studied alongside synthetic hemozoin crystals.
arxiv +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Andrea Kuemmerle +13 more
wiley +2 more sources
The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs
Advanced NanoBiomed Research, EarlyView.Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He +11 more
wiley +1 more source
, 2013 PURPOSE: It is increasingly common for health care professionals from developed countries to travel to developing regions of the world to learn or teach.
Drain +6 more
core +1 more source