Results 51 to 60 of about 91,276 (376)
Treating lupus patients with antimalarials: analysis of safety profile in a single-center cohort
Lupus, 2018 This longitudinal retrospective study aims at describing the safety profile and the reasons for discontinuation of antimalarials in patients with systemic lupus erythematosus (SLE) and discoid lupus erythematosus (DLE), focusing on ocular toxicity.
F. Spinelli +11 more
semanticscholar +1 more source
Antimalarial drug resistance [PDF]
Journal of Clinical Investigation, 2004 Malaria, the most prevalent and most pernicious parasitic disease of humans, is estimated to kill between one and two million people, mainly children, each year. Resistance has emerged to all classes of antimalarial drugs except the artemisinins and is responsible for a recent increase in malaria-related mortality, particularly in Africa.
openaire +5 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Parasite, 2007 Methylene blue (MB) is the oldest synthetic antimalarial. It is not used anymore as antimalarial but should be reconsidered. For this purpose we have measured its impact on both chloroquine sensitive and resistant Plasmodium strains.
Garavito G. +7 more
doaj +1 more source
Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants.
, 2009 Intermittent preventive treatment in infants (IPTi) is an effective and safe malaria control strategy. However, it remains unclear what antimalarials should be used to replace sulfadoxine-pyrimethamine (SP) when and where SP is no longer an effective ...
Cairns, Matthew +5 more
core +1 more source
Reappraisal of Antimalarials in Interferonopathies: New Perspectives for Old Drugs.
Current Medicinal Chemistry, 2018 The story of antimalarials as antinflammatory drugs dates back several centuries. Chinin, the extract of the Cinchona bark, has been exploited since the 18th century for its antimalarial and antifebrile properties. Later, during the Second World War, the
E. Piscianz +5 more
semanticscholar +1 more source
Hydroxychloroquine Associated with Lower Glomerular Filtration Rate Decline in Lupus Nephritis
Arthritis Care &Research, Accepted Article.Background Hydroxychloroquine (HCQ) protects kidney function in lupus nephritis (LN) by preventing flares, yet some cohort studies show no significant benefit in kidney function with HCQ. Clarifying these conflicting findings by showing early and long‐term benefits of HCQ on kidney function preservation is critical. Therefore, we analyzed data from our
Shivani Garg +9 more
wiley +1 more source
Scientific ReportsWe explored whether isotope ratio mass spectrometry (IRMS) is useful to investigate the origin of falsified antimalarials. Forty-four falsified and genuine antimalarial samples (artesunate, artemether-lumefantrine, dihydroartemisinin-piperaquine and ...
Paul N. Newton +6 more
doaj +1 more source
Malaria prevention in travelling children
South African Family Practice, 2012 Preventing malaria in children is often neglected. Prevention is very important, as malaria is still a significant cause of childhood mortality. Parents must be aware that the same measures must be taken by children to avoid being bitten by mosquitoes ...
S. Mathijs
doaj +1 more source
International Journal of Public Health, 2022 Objective: The objective was to describe the relationship between the location of care, the malaria test result, and the type of medicine consumed for the fever, and to determine whether community-based access to malaria testing reduced polypharmacy ...
Jeremiah Laktabai +8 more
doaj +1 more source