Results 81 to 90 of about 51,125 (324)
KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. [PDF]
, 2014 Preventing relapses of Plasmodium vivax malaria through a radical cure depends on use of the 8-aminoquinoline primaquine, which is associated with safety and compliance issues.
Borboa, Rachel +25 more
core +1 more source
Drug Design, Development and Therapy, 2018 Dan Liu,1,* Xiaodan Li,2,* Yonggang Zhang,3 Joey Sum-Wing Kwong,4,5 Ling Li,6 Yiyi Zhang,1 Chang Xu,6 Qianrui Li,1 Xin Sun,6 Haoming Tian,1 Sheyu Li1,7 1Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041,
Liu D +10 more
doaj
Memorias do Instituto Oswaldo Cruz, 2014 Due to the recent advances of atovaquone, a naphthoquinone, through clinical trials as treatment for malarial infection, 19 quinone derivatives with previously reported structures were also evaluated for blood schizonticide activity against the malaria ...
Nicolli Bellotti de Souza +6 more
doaj +1 more source
Acute Kidney Injury in a Patient Receiving Antimalarial Therapy: A Case Report
Haseki Tıp Bülteni, 2020 In this article, we present a case of Plasmodium falciparum malaria in a male patient who developed acute kidney injury during antimalarial treatment.
Heval Can Bilek +2 more
doaj +1 more source
Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline
Microbiology Spectrum, 2023 Malaria, especially Plasmodium falciparum infection, remains an enormous problem, and its treatment and control are seriously challenged by drug resistance. New antimalarial drugs are needed.
Oriana Kreutzfeld +20 more
doaj +1 more source
A mechanistic model quantifies artemisinin-induced parasite growth retardation in blood-stage Plasmodium falciparum infection [PDF]
, 2017 Falciparum malaria is a major parasitic disease causing widespread morbidity and mortality globally. Artemisinin derivatives---the most effective and widely-used antimalarials that have helped reduce the burden of malaria by 60% in some areas over the past decade---have recently been found to induce growth retardation of blood-stage Plasmodium ...
arxiv +1 more source
Chemical Components of the Dried Latex of Euphorbia resinifera Berg and Its Medicinal Features
Chemistry &Biodiversity, EarlyView.ABSTRACT A great deal of research has been carried out on the latex of Euphorbia resinifera Berg, which is an important source of several compounds of therapeutic and medicinal interest. Extraction, synthesis, and hemi synthesis pathways continue to reveal the existence of other new products with anticancer, antioxidant, antidiuretic, and antimalarial ...
Doaa Hammad +5 more
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 2015 Several species of Aspidospermaplants are used to treat diseases in the tropics, including Aspidosperma ramiflorum, which acts against leishmaniasis, an activity that is experimentally confirmed.
Anna CC Aguiar +5 more
doaj +1 more source
PlasmoFAB: A Benchmark to Foster Machine Learning for Plasmodium falciparum Protein Antigen Candidate Prediction [PDF]
arXiv, 2023 Motivation: Machine learning methods can be used to support scientific discovery in healthcare-related research fields. However, these methods can only be reliably used if they can be trained on high-quality and curated datasets. Currently, no such dataset for the exploration of Plasmodium falciparum protein antigen candidates exists.
arxiv
Chemistry &Biodiversity, EarlyView.Flow chat for the quantitative and qualitative profiles and the biological activities of T. violacea fruits and seeds. ABSTRACT Tulbaghia violacea is an established medicinal plant that is indigenous to southern Africa. All its plant parts have been profiled for their phytochemical constituents and medicinal potentials except for the seeds and fruits ...
Rebecca Opeyemi Oyerinde +1 more
wiley +1 more source