Results 21 to 30 of about 2,125 (132)

New Therapeutic Targets for Mood Disorders [PDF]

, 2010
Existing pharmacological treatments for bipolar disorder (BPD) and major depressive disorder (MDD) are often insufficient for many patients. Here we describe a number of targets/compounds that clinical and preclinical studies suggest could result in ...
Carlos A. Zarate, Cristina Wheeler-Castillo, David Latov, Giacomo Salvadore, Ioline D. Henter, Jacqueline Baumann, Lobna Ibrahim, Nancy DiazGranados, Rodrigo Machado-Vieira   +8 more
core   +1 more source

Lithium and the risk of chronic kidney disease: A population‐based case–control study

Basic &Clinical Pharmacology &Toxicology, Volume 131, Issue 2, Page 129-137, August 2022., 2022
Abstract The association between lithium use and chronic kidney disease (CKD) needs further evaluation. We aimed to investigate this association using Danish nationwide healthcare registers and routinely collected plasma creatinine measurements from the Funen Laboratory Cohort.
Mikkel Højlund, Jane Sterndorff Winkel, Mads Nybo, Jesper Hallas, Daniel Pilsgaard Henriksen, Per Damkier   +5 more
wiley   +1 more source

Rapid cycling bipolar disorder: Literature review on pharmacological treatment illustrated by a case report on ketamine

Brain and Behavior, Volume 12, Issue 2, February 2022., 2022
The main objective of this review was to propose a critical review of the literature and to rank the pharmacological agent using a Level Of Evidence (LEO) adapted from the Center for Evidence‐Based Medicine, and to illustrate it with a case report on off‐label intravenous ketamine.
Alexis Bourla, Florian Ferreri, Thomas Baudry, Vincent Panizzi, Vladimir Adrien, Stéphane Mouchabac   +5 more
wiley   +1 more source

Real‐World Long‐Term Experience on Endoxifen in Bipolar Disorder with Psychotic Symptoms

Case Reports in Psychiatry, Volume 2022, Issue 1, 2022., 2022
Evidence suggests that inhibition of protein kinase C (PKC) signalling may have a contributing role in the treatment of bipolar affective disorder (BPAD). Endoxifen, an active metabolite of tamoxifen, is a potent direct PKC inhibitor. This report presents a severe case of a BPAD patient with a baseline Young Mania Rating Scale (YMRS) score of 49 ...
Vikas Thanvi, Yasuhiro Kaneda
wiley   +1 more source

HOW ASSESS DRUGS IN THE TREATMENT OF ACUTE BIPOLAR MANIA ?

Frontiers in Pharmacology, 2013
Bipolar affective disorder is a serious mental disease associated with significant morbidity and mortality. Good-quality research available to guide treatment strategies remains insufficient, particularly with regard to manic or hypomanic episodes.
Michel eBourin, Florence eThibaut
doaj   +1 more source

Donepezil and related cholinesterase inhibitors as mood and behavioral controlling agents. [PDF]

, 2000
Acetylcholinesterase inhibitors (ChEIs) enhance neuronal transmission by increasing the availability of acetylcholine in muscarinic and nicotinic receptors.
A Grob, BJ Carroll, BJ Steinberg, CH Dyck van, D Kaufer, DE Giles, DJ Safer, DS Geldmacher, DS Janowsky, DS Janowsky, DS Janowsky, DS Janowsky, DW Rowntree, EF Willoughby, JC Morris, JL Cummings, JL Cummings, JM Cooney, JM Cooney, KL Davis, KL Lanctot, LJ Thal, M Rosler, MA Raskind, MA Raskind, MA Raskind, MB Bowers, MF Weiner, MS Mega, MS Mega, N Sitaram, PJ Goodnick, PN Tariot, PS Kishnani, RE Becker, RT Rubin, SC Risch, SP Hoopes, SP Wengel, SS Leong, T Burt, Tal Burt, WJ Burke, YM Greene   +43 more
core   +1 more source

Real-world effectiveness of mood stabilizers on self-harm and suicide attempts in patients with bipolar disorder: A 2-year mirror-image study

Journal of Affective Disorders Reports, 2021
Background: Bipolar disorder (BD) is associated with a high incidence of intentional self-harm and suicide attempts (SH/SA), however the effectiveness of mood-stabilizers on SH/SA remains controversial.
Oskar Hougaard Jefsen, Søren Dinesen Østergaard, Jimmi Nielsen, Christopher Rohde   +3 more
doaj  

Factors modifying drug and placebo responses in randomized trials for bipolar mania [PDF]

, 2014
Factors modifying drug and placebo responses in randomized trials for bipolar mania. Yildiz A, Vieta E, Tohen M, Baldessarini RJ. Source Department of Psychiatry, Dokuz Eylül University, Izmir, Turkey.
Baldessarini, Ross J., Tohen, Mauricio, Vieta i Pascual, Eduard, 1963-, Yildiz, Aysegül   +3 more
core   +2 more sources

Transtornos de personalidade, psicopatia e serial killers Personality disorders, psychopathy and serial killers

Brazilian Journal of Psychiatry, 2006
OBJETIVO: Apresentar as características básicas dos diversos transtornos específicos de personalidade, mas centrando-se no transtorno de personalidade anti-social, fazendo sua diferenciação com psicopatia.
Hilda C P Morana, Michael H Stone, Elias Abdalla-Filho   +2 more
doaj   +1 more source

Treatment of psychotic symptoms in bipolar disorder with aripiprazole monotherapy: A meta-analysis [PDF]

, 2009
Background: We present a systematic review and meta-analysis of the available clinical trials concerning the usefulness of aripiprazole in the treatment of the psychotic symptoms in bipolar disorder.Methods: A systematic MEDLINE and repository search ...
A Cipriani, A Martinez-Aran, AH Young, B Corbella, C Toni, DJ Muzina, DP Prata, E Vieta, E Vieta, Eduard Vieta, EK Green, Frank Schmidt, G Sachs, G Selva, GS Sachs, GW Currier, H Akiskal, HG El-Sayeh, HS Akiskal, J Hunter, JG Storosum, K Aitchison, KN Fountoulakis, KN Fountoulakis, KN Fountoulakis, KN Fountoulakis, KN Fountoulakis, KN Fountoulakis, KN Fountoulakis, KN Fountoulakis, Konstantinos N Fountoulakis, LA Smith, M Garcia-Amador, M Maziade, M Sanford, M Tohen, MC O'Donovan, ME Thase, N Craddock, PB Mitchell, PE Keck, PE Keck Jr, PE Keck Jr, PE Keck Jr, PG Janicak, R Lenox, RH Perlis, RS McIntyre, RS McIntyre, T Kikuchi, T Suppes, Xenia Gonda, Y Oshiro   +52 more
core   +2 more sources