Results 41 to 50 of about 16,625 (206)
Frontiers in Oncology, 2021 BackgroundPemetrexed and gemcitabine are both antimetabolites drugs approved in advanced non-small cell lung cancer (NSCLC). Their toxicity profile is well known. However, rare vascular side effects can occur such as vascular acrosyndromes and especially
Margaux Geier +6 more
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Mechanism of Action and Use of Radiomimetic Compounds : Part 1 – Alkylating Agents and Antimetabolites [PDF]
, 2022 Radiomimetic substances are drugs producing similar symptoms in living organisms as ionising radiation does. They constitute a special subgroup of carcinogen, mutagen, teratogen compounds; their common characteristic is to cause DNA breaks and/or to ...
Deli, Gábor
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Agronomy, 2020 Conventional weed control practices have generated serious issues related to the environment and human health. Therefore, there is a demand for the development of alternative techniques for sustainable agriculture.
Tasawar Abbas +6 more
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Apoptotic enteropathy caused by antimetabolites and TNF-α antagonists
, 2014 AIMS: To investigate whether drugs others than mycophenolic acid and ipilimumab might cause graft-versus-host-like apoptotic enteropathy, the clinicopathological findings in four patients were examined who had developed watery diarrhoea and apoptotic ...
Rogler, Gerhard +6 more
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Oftalʹmologiâ, 2017 The article describes modern approaches for controlling wound healing after fistulizing glaucoma surgery. The review recounts international experience of steroidal and nonsteroidal anti-inflammatory drug and their efficacy research study ...
S. Yu. Petrov
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Advanced Science, EarlyView.Safe and precise bioorthogonal therapy of tumors was achieved by an ultrasound‐responsive heterostructured nanoreactor with on‐demand catalytic activity. Under piezoelectric catalysis, the system undergoes reversible Pd2+/Pd0 redox cycling, concurrently enabling spatiotemporally controlled prodrug activation and self‐terminating catalytic dose ...
Daqing Xia +9 more
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PharmaceuticalsOptimizing immunosuppressant dosing presents significant challenges in kidney transplantation due to narrow therapeutic ranges and considerable inter-patient pharmacokinetic differences.
Sholpan Altynova +5 more
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American Journal of Hematology, EarlyView.ABSTRACT Quizartinib is a tyrosine kinase inhibitor with single agent activity in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) and has demonstrated efficacy in first‐line therapy when combined with intensive chemotherapy in both FLT3 ITD‐negative and positive AML.
Teresa Bernal +29 more
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MODERN ONCO DRUG FOR INTERNAL USE
Фармация и фармакология (Пятигорск), 2018 Despite the development of biotherapy, chemotherapy remains one of the main methods of treatment of cancer patients. Currently, there are more than 100 anticancer drug substances, however, every year new drugs enter clinical practice and various ...
O. L. Orlova +7 more
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Syntheses of Antimetabolites [PDF]
, 1970 In these studies several different types of antimetabolites were synthesized, and their biological effects were examined in various assay systems. More extensive investigations were done in microbial systems in which many of the compounds proved to be ...
Clifton, George Gil
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