Results 71 to 80 of about 15,196 (172)
International Journal for Parasitology: Drugs and Drug Resistance, 2017 Leishmania pyrimidine salvage is replete with opportunities for therapeutic intervention with enzyme inhibitors or antimetabolites. Their uptake into cells depends upon specific transporters; therefore it is essential to establish whether various ...
Khalid J.H. Alzahrani +7 more
doaj +1 more source
Pigment Cell &Melanoma Research, Volume 39, Issue 4, July 2026.ADI‐PEG20 enhances melphalan‐induced DNA DSBs in UM cells. We describe potentiation of DNA DSBs in UM cell lines upon treatment with ADI‐PEG20 and melphalan (92.1 cells with STRIDE by intoDNA). ADI‐PEG20 suppresses multiple members of the FA pathway—a known resistance mechanism for melphalan—providing a rationale for exploring this drug combination in ...
Iuliia Pavlyk +10 more
wiley +1 more source
Cisplatin resistance coupled to enhanced sensitivity to metabolic interventions
Molecular & Cellular Oncology, 2018 Specific metabolic alterations have recently been observed in cisplatin-resistant cancers. As a result, cisplatin resistance can be overcome by co-administration of pyridoxine, and cisplatin-resistant cancer cells become exquisitely sensitive to killing ...
Maria Castedo +2 more
doaj +1 more source
Indian Journal of Ophthalmology. Case ReportsWe report four cases of use of Inj mitomycin C (MMC) (20 mcg) in the subconjunctival space adjacent to bleb of MMC augmented trabeculectomies, followed by bleb massage regimen.
Anukool S Deshpande, Sushama N Rahate
doaj +1 more source
Antimetabolites in the treatment of arthritis:current status of the use of antimetabolites
Nucleosides, nucleotides & nucleic acids, 2004 Rheumatoid arthritis (RA) is an autoimmune disease characterized by a chronic inflammation of the synovial joints and infiltration of blood-derived cells. In daily practice rheumatologists use the antimetabolites methotrexate (MTX) and leflunomide for the treatment of patients with rheumatoid arthritis.
Dijkmans, B A C, Jansen, G
openaire +2 more sources
Sequential versus Combined Glaucoma and Cataract Procedures in Siriraj Hospital
Siriraj Medical Journal, 2006 Objective: To compare the efficacy of intraocular pressure (IOP) control after combined cataract and trabeculectomy with sequential cataract surgery after trabeculectomy, both with and without antimetabolites.
Darin Sakiyalak +2 more
doaj
A Study of Efficacy of Intraoperative Application of Mitomycin-C in Endoscopic Dacryocystorhinostomy
Bengal Journal of Otolaryngology and Head Neck Surgery, 2018 Introduction Common cause for failure of endonasal dacryocystorhinostomy is closure of the intranasal ostium usually due to granulation tissue formation.
Harikesh Sharma, Ajay Mallick
doaj
Indian Journal of Ophthalmology, 1997 Thirty-three eyes of 33 patients were prospectively evaluated to study the short term efficacy, safety, and overall surgical outcome of initial trabeculectomy for primary glaucomas with adjunctive intraoperative or postoperative 5-Fluorouracil (5-FU) use.
Lamba P, Pandey P, Raina U, Krishna V
doaj
Differential Effects of T-Cell Inhibitors and Antimetabolites on Graft Survival in High-Risk Penetrating Keratoplasty: A Tertiary Center Experience. [PDF]
Ophthalmol SciChokesuwattanaskul S +4 more
europepmc +1 more source