Results 31 to 40 of about 90,280 (287)
Antibiotics, 2023 Here we designed and synthesized analogs of two antimicrobial peptides, namely C10:0-A2, a lipopeptide, and TA4, a cationic α-helical amphipathic peptide, and used non-proteinogenic amino acids to improve their therapeutic properties. The physicochemical
Maria Veronica Humpola +6 more
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Cationic Antimicrobial Peptide Resistance in Neisseria meningitidis [PDF]
Journal of Bacteriology, 2005 ABSTRACT Cationic antimicrobial peptides (CAMPs) are important components of the innate host defense system against microbial infections and microbial products. However, the human pathogen Neisseria meningitidis is intrinsically highly resistant to CAMPs, such as polymyxin B (PxB) (MIC ≥ 512 μg/ml).
Yih-Ling, Tzeng +6 more
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Interaction of Cationic Antimicrobial Peptides with Model Membranes [PDF]
Journal of Biological Chemistry, 2001 A series of natural and synthetic cationic antimicrobial peptides from various structural classes, including alpha-helical, beta-sheet, extended, and cyclic, were examined for their ability to interact with model membranes, assessing penetration of phospholipid monolayers and induction of lipid flip-flop, membrane leakiness, and peptide translocation ...
L, Zhang, A, Rozek, R E, Hancock
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Frontiers in Immunology, 2020 Cationic antimicrobial peptides (AMPs) are active immune effectors of multicellular organisms and are also considered as new antimicrobial drug candidates.
Alexandro Rodríguez-Rojas +8 more
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Antibacterial activity of active peptide from marine macroalgae Chondrus crispus protein hydrolysate against Staphylococcus aureus [PDF]
Pharmacia, 2023 Macroalgae is a protein source with the potential to yield antimicrobial peptides (AMPs) that exhibit a wide range of biological activities. This study aimed to find bioactive peptide-based antibacterial compounds from marine macroalgae Chondrus crispus ...
Ahmad Habibie +3 more
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Antimicrobial peptides: the role of hydrophobicity in the alpha helical structure [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2013 The antimicrobial peptides (AMPs) are a class of molecule obtained from plants, insects, animals, and humans. These peptides have been classified into five categories: 1. Anionic peptide, 2. Linear alpha helical cationic peptide, 3.
Pandurangan Perumal, Vijaya P. Pandey
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Functions of Cationic Host Defense Peptides in Immunity
Pharmaceuticals, 2016 Cationic host defense peptides are a widely distributed family of immunomodulatory molecules with antimicrobial properties. The biological functions of these peptides include the ability to influence innate and adaptive immunity for efficient resolution ...
Mahadevappa Hemshekhar +2 more
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Interaction of cationic antimicrobial peptides with Mycoplasma pulmonis [PDF]
FEBS Letters, 2013 We investigated the mode of action underlying the anti‐mycoplasma activity of cationic antimicrobial peptides (AMPs) using four known AMPs and Mycoplasma pulmonis as a model mycoplasma. Scanning electron microscopy revealed that the integrity of the M.
Park, Ho Jin +5 more
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Frontiers in Chemistry, 2017 The preclinical in vitro and in vivo benchmark figures of cationic antimicrobial peptides have to be revisited based on the newly discovered alternative modes of action.
Laszlo Otvos, Laszlo Otvos
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Antibiotics, 2020 Ocellatins are a family of antimicrobial peptides found exclusively in the Leptodactylus genus. To date, 10 species have been studied and more than 23 peptides described.
Mariela M. Marani +5 more
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