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Antimicrobial peptides of vertebrates
Current Opinion in Immunology, 1998The past year brought several discoveries that focused attention on antimicrobial peptides on epithelial surfaces. The malfunction of these substances was implicated as a cause of airway infections in cystic fibrosis. Other highlights included new insights into the relative selectivity of antimicrobial peptides for microbial membranes, their primary ...
T, Ganz, R I, Lehrer
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Antimicrobial peptides in plants.
2010AbstractThis chapter provides an overview of plant antimicrobial peptides. It mainly focuses on one particular class of plant defence peptides, namely the cyclotides, which have been discovered over the last decade in plants from the Rubiaceae, Violaceae and Cucurbitaceae families.
Kaas, Quentin +3 more
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Antimicrobial Peptides: An Introduction
2016The "golden era" of antibiotic discovery has long passed, but the need for new antibiotics has never been greater due to the emerging threat of antibiotic resistance. This urgency to develop new antibiotics has motivated researchers to find new methods to combat pathogenic microorganisms resulting in a surge of research focused around antimicrobial ...
Evan F, Haney +2 more
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Antimicrobial Peptides in the Airway
2006The airway provides numerous defense mechanisms to prevent microbial colonization by the large numbers of bacteria and viruses present in ambient air. An important component of this defense is the antimicrobial peptides and proteins present in the airway surface fluid (ASF), the mucin-rich fluid covering the respiratory epithelium. These include larger
D M, Laube +4 more
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Antimicrobial Peptides of Lactoferrin
1994Lactoferrin was found to contain an antimicrobial sequence near its N-terminus which appears to function by a mechanism distinct from iron chelation. Antimicrobial peptides representing this domain were isolated following pepsin cleavage of human lactoferrin and bovine lactoferrin.
M, Tomita +3 more
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Descriptors for antimicrobial peptides
Expert Opinion on Drug Discovery, 2011A frightening increase in the number of isolated multidrug resistant bacterial strains linked to the decline in novel antimicrobial drugs entering the market is a great cause for concern. Cationic antimicrobial peptides (AMPs) have lately been introduced as a potential new class of antimicrobial drugs, and computational methods utilizing molecular ...
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Antimicrobial Peptides: The LPS Connection
2009An expanding body of evidence is rendering manifest that many cationic antimicrobial peptides are endowed with different properties and activities, well beyond their direct action on microbes. One of the most interesting and potentially important research avenue on the alternative use of antimicrobial peptides grounds on their affinity toward ...
GIULIANI A, PIRRI G, RINALDI, ANDREA
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In Silico Design of Antimicrobial Peptides
2014The rapid spread of drug-resistant pathogenic microbial strains has created an urgent need for the development of new anti-infective molecules, having different mechanism of action in comparison to existing drugs. Natural antimicrobial peptides (AMPs) represent a novel class of molecules with a broad spectrum of activity and a low rate in inducing ...
Maccari, Giuseppe +2 more
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The Potential of Human Peptide LL-37 as an Antimicrobial and Anti-Biofilm Agent
Antibiotics, 2021Joerg Overhage
exaly
Development of disulfide bond crosslinked antimicrobial peptide hydrogel
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2021Fengyi Cao, Lin Mei, Genxing Zhu
exaly