Results 21 to 30 of about 262,820 (287)
Prediction of antimicrobial activity of a food peptide and evaluation of its effectiveness in vitro
Vestnik MGTU, 2023 Food antimicrobial peptides are increasingly relevant in the treatment of bacterial infections and have a number of advantages in comparison with drugs: slower emergence of resistance in bacterial strains, high activity against antibiotic films and ...
Merzlyakova N. V. +4 more
doaj +1 more source
Antimicrobial dendrimeric peptides [PDF]
European Journal of Biochemistry, 2002 Dendrimeric peptides selective for microbial surfaces have been developed to achieve broad antimicrobial activity and low hemolytic activity to human erythrocytes. The dendrimeric core is an asymmetric lysine branching tethered with two to eight copies of a tetrapeptide (R4) or an octapeptide (R8).
James P, Tam, Yi-An, Lu, Jin-Long, Yang
openaire +2 more sources
The frog skin-derived antimicrobial peptide esculentin-1a(1-21)nh2 promotes the migration of human hacat keratinocytes in an egf receptor-dependent manner: a novel promoter of human skin wound healing? [PDF]
, 2015 One of the many functions of skin is to protect the organism against a wide range of pathogens. Antimicrobial peptides (AMPs) produced by the skin epithelium provide an effective chemical shield against microbial pathogens. However, whereas antibacterial/
Cappiello, Floriana +6 more
core +7 more sources
Antimicrobial peptides: agents of border protection for companion animals. [PDF]
, 2012 Over the past 20 years, there have been significant inroads into understanding the roles of antimicrobial peptides in homeostatic functions and their involvement in disease pathogenesis.
Affolter, Verena K +2 more
core +1 more source
Antimicrobial Peptide Nanomaterials
, 2023 Antimicrobial peptides exist throughout nature and are produced by multicellular organisms as a defence mechanism against pathogenic microbes. Multi-drug resistant bacteria pose a serious threat to public health. In the increasing absence of new antibiotic agents, there is a need for the development of novel strategies to target bacterial infections ...
Coulter, Sophie, Laverty, Garry
openaire +3 more sources
Frontiers in Chemistry, 2022 Peptide-Peptide Nucleic Acid (PNA) conjugates targeting essential bacterial genes have shown significant potential in developing novel antisense antimicrobials. The majority of efforts in this area are focused on identifying different PNA targets and the
Nitin A. Patil +12 more
doaj +1 more source
Antimicrobial Peptides in Action [PDF]
Journal of the American Chemical Society, 2006 Molecular dynamics simulations of the magainin MG-H2 peptide interacting with a model phospholipid membrane have been used to investigate the mechanism by which antimicrobial peptides act. Multiple copies of the peptide were randomly placed in solution close to the membrane.
Leontiadou, H. +2 more
openaire +3 more sources
Destabilization of α-helical structure in solution improves bactericidal activity of antimicrobial peptides: Opposing effects on bacterial and viral targets [PDF]
, 2016 We have previously examined the mechanism of antimicrobial peptides on the outer membrane of vaccinia virus. Here we show that the formulation of peptides LL37 and magainin-2B amide in polysorbate 20 (Tween-20™) results in greater reductions in virus ...
Beck, Konrad +4 more
core +2 more sources
Hydrocarbon Stapled Antimicrobial Peptides [PDF]
The Protein Journal, 2018 Abstract Antimicrobial peptides are promising candidates for anti-infective pharmaceuticals. Unfortunately, because of their low proteolytic and chemical stability, their usage is generally narrowed down to topical formulations. Until now, numerous approaches to increase peptide stability have been proposed.
Dorian Migoń +2 more
openaire +2 more sources
Frontiers in Marine Science, 2022 The overuse of antibiotics leads to the emergence of bacterial resistance, which poses a serious threat to aquaculture. Antimicrobial peptides (AMPs) display excellent antimicrobial activity and are thought to be the most feasible replacements for ...
Yijun Lin +8 more
doaj +1 more source