Results 31 to 40 of about 146,073 (265)
Antibiotics, 2020 The increasing number of infections caused by multidrug-resistant bacteria requires an intensified search for new antibiotics. Pep19-4LF is a synthetic antimicrobial peptide (GKKYRRFRWKFKGKLFLFG) that was previously designed with the main focus on high ...
Philip Storck +10 more
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Peptide Antimicrobial Agents [PDF]
Clinical Microbiology Reviews, 2006 SUMMARYAntimicrobial host defense peptides are produced by all complex organisms as well as some microbes and have diverse and complex antimicrobial activities. Collectively these peptides demonstrate a broad range of antiviral and antibacterial activities and modes of action, and it is important to distinguish between direct microbicidal and indirect ...
Håvard, Jenssen +2 more
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Antimicrobial Peptide–Polymer Conjugates
Pharmaceutics, 2022 The global health threat imposed by the fast spread of antibiotic-resistant bacteria is directing research not only towards the discovery of new antibacterial molecules but also to the repurposing of old drugs, while improving their efficiency and safety
Martijn Riool +2 more
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A Review of Structural Characteristics and Structure-Function Relationship of Two-Peptide (Class IIb) Bacteriocins [PDF]
Shipin Kexue, 2023 The two-peptide (class IIb) bacteriocins are generally thermostable small-molecule (< 10 kDa) two-component antimicrobial peptides produced by Gram-positive bacteria.
ZHAO Penghao, SHANG Jiacui, CHEN Yuhan, DUAN Bofan, MENG Xiangchen
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Upsala Journal of Medical Sciences, 2014 With increasing antibiotics resistance, there is an urgent need for novel infection therapeutics. Since antimicrobial peptides provide opportunities for this, identification and optimization of such peptides have attracted much interest during recent years.
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Snake Cathelicidin NA-CATH and Smaller Helical Antimicrobial Peptides Are Effective against Burkholderia thailandensis. [PDF]
PLoS Neglected Tropical Diseases, 2015 Burkholderia thailandensis is a Gram-negative soil bacterium used as a model organism for B. pseudomallei, the causative agent of melioidosis and an organism classified category B priority pathogen and a Tier 1 select agent for its potential use as a ...
Ryan J Blower +2 more
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Peptide Stapling Applied to Antimicrobial Peptides
Antibiotics, 2023 Antimicrobial peptides (AMPs) are considered a promising therapeutic approach against multi-drug resistant microorganisms. Besides their advantages, there are limitations to be overcome so that these molecules can become market competitive. One of the biggest limitations is proteolytic susceptibility, which could be overcome by structural modifications
Ana Laura Pereira Lourenço +4 more
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Pharmaceuticals, 2014 There is great interest in the development of antimicrobial peptides as a potentially novel class of antimicrobial agents. Several structural determinants are responsible for the antimicrobial and cytolytic activity of antimicrobial peptides.
Ammar Almaaytah +6 more
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Antimicrobial Peptides and Colitis [PDF]
Current Pharmaceutical Design, 2012 Antimicrobial peptides (AMPs) are important components of innate immunity. They are often expressed in response to colonic inflammation and infection. Over the last several years, the roles of several antimicrobial peptides have been explored. Gene expression of many AMPs (beta defensin HBD2-4 and cathelicidin) is induced in response to invasion of gut
Samantha, Ho +2 more
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Siliao yanjiu, 2021 The experiment studied the effect of different levels of antimicrobial peptides on growth performance, slaughter performance, meat quality and immune function of broilers.
Zhong-xin GUO, Tian-qi WANG
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