Results 21 to 30 of about 146,943 (259)

Molecular cloning, expression and in vitro analysis of soluble cationic synthetic antimicrobial peptide from salt-inducible Escherichia coli GJ1158 [PDF]

open access: yesJournal of BioScience and Biotechnology, 2013
Antimicrobial peptides are the upcoming therapeutic molecules as alternative drugs to the existing antibiotics owing to their potent action against pathogenic microorganisms.
Jawahar Babu Peravali   +9 more
doaj  

A Review of Structural Characteristics and Structure-Function Relationship of Two-Peptide (Class IIb) Bacteriocins [PDF]

open access: yesShipin Kexue, 2023
The two-peptide (class IIb) bacteriocins are generally thermostable small-molecule (< 10 kDa) two-component antimicrobial peptides produced by Gram-positive bacteria.
ZHAO Penghao, SHANG Jiacui, CHEN Yuhan, DUAN Bofan, MENG Xiangchen
doaj   +1 more source

The pseudokinase NIPI-4 is a novel regulator of antimicrobial peptide gene expression. [PDF]

open access: yesPLoS ONE, 2012
Hosts have developed diverse mechanisms to counter the pathogens they face in their natural environment. Throughout the plant and animal kingdoms, the up-regulation of antimicrobial peptides is a common response to infection. In C.
Sid Ahmed Labed   +4 more
doaj   +1 more source

Fatty Acid Conjugation Leads to Length-Dependent Antimicrobial Activity of a Synthetic Antibacterial Peptide (Pep19-4LF)

open access: yesAntibiotics, 2020
The increasing number of infections caused by multidrug-resistant bacteria requires an intensified search for new antibiotics. Pep19-4LF is a synthetic antimicrobial peptide (GKKYRRFRWKFKGKLFLFG) that was previously designed with the main focus on high ...
Philip Storck   +10 more
doaj   +1 more source

Antimicrobial Peptide–Polymer Conjugates

open access: yesPharmaceutics, 2022
The global health threat imposed by the fast spread of antibiotic-resistant bacteria is directing research not only towards the discovery of new antibacterial molecules but also to the repurposing of old drugs, while improving their efficiency and safety
Martijn Riool   +2 more
doaj   +1 more source

Antimicrobial Peptides in Action [PDF]

open access: yesJournal of the American Chemical Society, 2006
Molecular dynamics simulations of the magainin MG-H2 peptide interacting with a model phospholipid membrane have been used to investigate the mechanism by which antimicrobial peptides act. Multiple copies of the peptide were randomly placed in solution close to the membrane.
Leontiadou, H.   +2 more
openaire   +5 more sources

Snake Cathelicidin NA-CATH and Smaller Helical Antimicrobial Peptides Are Effective against Burkholderia thailandensis. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2015
Burkholderia thailandensis is a Gram-negative soil bacterium used as a model organism for B. pseudomallei, the causative agent of melioidosis and an organism classified category B priority pathogen and a Tier 1 select agent for its potential use as a ...
Ryan J Blower   +2 more
doaj   +1 more source

Antimicrobial peptides

open access: yesUpsala Journal of Medical Sciences, 2014
With increasing antibiotics resistance, there is an urgent need for novel infection therapeutics. Since antimicrobial peptides provide opportunities for this, identification and optimization of such peptides have attracted much interest during recent years.
openaire   +2 more sources

Enhanced Antimicrobial Activity of AamAP1-Lysine, a Novel Synthetic Peptide Analog Derived from the Scorpion Venom Peptide AamAP1

open access: yesPharmaceuticals, 2014
There is great interest in the development of antimicrobial peptides as a potentially novel class of antimicrobial agents. Several structural determinants are responsible for the antimicrobial and cytolytic activity of antimicrobial peptides.
Ammar Almaaytah   +6 more
doaj   +1 more source

Peptide Self-Assembly Is Linked to Antibacterial, but Not Antifungal, Activity of Histatin 5 Derivatives

open access: yesmSphere, 2020
The rise of multidrug-resistant pathogens has awakened interest in new drug candidates such as antimicrobial peptides and their derivatives. Recent work suggests that some antimicrobial peptides have the ability to self-assemble into ordered amyloid-like
Lee Schnaider   +5 more
doaj   +1 more source

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