Results 31 to 40 of about 264,067 (270)

Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity. [PDF]

, 2017
Peptide-based supramolecular assemblies are a promising class of nanomaterials with important biomedical applications, specifically in drug delivery and tissue regeneration.
Adler-Abramovich, Lihi, Brahmachari, Sayanti, Bychenko, Darya, DeGrado, William F, Gazit, Ehud, Kolusheva, Sofiya, Mensa, Bruk, Schmidt, Nathan W, Schnaider, Lee, Shaham-Niv, Shira, Shimon, Linda JW   +10 more
core   +3 more sources

Targeted Antimicrobial Peptides [PDF]

Frontiers in Immunology, 2012
The existence of natural antimicrobial substances, contributing to the mechanisms of host defenses, has been recognized since the late nineteenth century. In 1963, the in vitro antibacterial activity of leukocyte extracts was attributed to basic proteins.
openaire   +3 more sources

A Review of Structural Characteristics and Structure-Function Relationship of Two-Peptide (Class IIb) Bacteriocins [PDF]

Shipin Kexue, 2023
The two-peptide (class IIb) bacteriocins are generally thermostable small-molecule (< 10 kDa) two-component antimicrobial peptides produced by Gram-positive bacteria.
ZHAO Penghao, SHANG Jiacui, CHEN Yuhan, DUAN Bofan, MENG Xiangchen
doaj   +1 more source

Cn-AMP2 from green coconut water is an anionic anticancer peptide [PDF]

, 2014
Globally, death due to cancers is likely to rise to over 20 million by 2030,which has created an urgent need for novel approaches to anticancer therapies such as the development of host defence peptides.
Al-Benna, Avner, Balderas-Renteria, Bray, Chan, Cho, Cho, Cragg, Cragg, Dawson, Dennison, Dennison, Dennison, Dennison, Gaspar, Gotay, Harris, Harris, Harris, Harris, Harris, Hess, Hogberg, Khazir, Li, Lumb, Malde, Mandal, Mandal, Martin Sabroso, Newman, Nicolas, Oh, Pasupuleti, Phoenix, Phoenix, Phoenix, Phoenix, Prabhu, Prabhu, Rajanbabu, Riedl, Saraswathy, Shekhar, Song, Tsuda, Unnati, Urruticoechea, Van der Spoel, Varadhachary, Wall, Wang, Wang, Whitmore, Whitmore, Whitmore, Yeung   +56 more
core   +1 more source

Design of a novel tryptophan-rich membrane-active antimicrobial peptide from the membrane-proximal region of the HIV glycoprotein, gp41

Beilstein Journal of Organic Chemistry, 2012
A number of physicochemical characteristics have been described which contribute to the biological activity of antimicrobial peptides. This information was used to design a novel antimicrobial peptide sequence by using an intrinsically inactive membrane ...
Evan F. Haney, Leonard T. Nguyen, David J. Schibli, Hans J. Vogel   +3 more
doaj   +1 more source

A novel antibacterial peptide derived from Crocodylus siamensis haemoglobin hydrolysate induces membrane permeabilization causing iron dysregulation, oxidative stress and bacterial death [PDF]

, 2017
Aims A novel antibacterial peptide from Crocodylus siamensis haemoglobin hydrolysate (CHH) was characterized for antimicrobial activity. Methods and Results CHHs were hydrolysed for 2 h (2 h-CHH), 4 h (4h-CHH), 6 h (6 h-CHH) and 8 h (8 h-CHH). The
Adje, Ali, Arroume, Arroume, Chitemerere, Daoud, Froidevaux, Gault, Jandaruang, Jangpromma, Kabbua, Maddocks, Maijaroen, Mbah, Michel, Miller, Osman, Pakdeesuwan, Pata, Phosri, Phosri, Sato, Schwyn, Solanky, Song, Srihongthong, Vasilchenko, Winkelmann, Yu, Zheng   +29 more
core   +2 more sources

Wheat antimicrobial peptides

Russian Journal of Genetics: Applied Research, 2013
Antimicrobial peptides (AMPs) are low-molecular-weight defense polypeptides, produced in all living organisms either constitutively or upon perception of signals from pathogenic microorganisms. They are important components of the immune system in both animals and plants. AMPs differ in structure and mode of action. Most of them belong to cysteine-rich
T. I. Odintsova, T. V. Korostyleva, L. L. Utkina, Ya. A. Andreev, A. A. Slavokhotova, E. A. Istomina, V. A. Pukhal’skii, T. A. Egorov   +7 more
openaire   +2 more sources

Molecular cloning, expression and in vitro analysis of soluble cationic synthetic antimicrobial peptide from salt-inducible Escherichia coli GJ1158 [PDF]

Journal of BioScience and Biotechnology, 2013
Antimicrobial peptides are the upcoming therapeutic molecules as alternative drugs to the existing antibiotics owing to their potent action against pathogenic microorganisms.
Jawahar Babu Peravali, Seetha Ram Kotra, Gogata Ravi Teja, Prudvi Nelavalli, Kona Prasad, Anmol Kumar, Kunkalaguntla V. Rajesh, Kota Sobha, Ruther Nelson, Krishna Kanth Pulicherla   +9 more
doaj  

Fatty Acid Conjugation Leads to Length-Dependent Antimicrobial Activity of a Synthetic Antibacterial Peptide (Pep19-4LF)

Antibiotics, 2020
The increasing number of infections caused by multidrug-resistant bacteria requires an intensified search for new antibiotics. Pep19-4LF is a synthetic antimicrobial peptide (GKKYRRFRWKFKGKLFLFG) that was previously designed with the main focus on high ...
Philip Storck, Florian Umstätter, Sabrina Wohlfart, Cornelius Domhan, Christian Kleist, Julia Werner, Klaus Brandenburg, Stefan Zimmermann, Uwe Haberkorn, Walter Mier, Philipp Uhl   +10 more
doaj   +1 more source

The pseudokinase NIPI-4 is a novel regulator of antimicrobial peptide gene expression. [PDF]

PLoS ONE, 2012
Hosts have developed diverse mechanisms to counter the pathogens they face in their natural environment. Throughout the plant and animal kingdoms, the up-regulation of antimicrobial peptides is a common response to infection. In C.
Sid Ahmed Labed, Shizue Omi, Martha Gut, Jonathan J Ewbank, Nathalie Pujol   +4 more
doaj   +1 more source