Results 31 to 40 of about 262,820 (287)

Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity. [PDF]

, 2017
Peptide-based supramolecular assemblies are a promising class of nanomaterials with important biomedical applications, specifically in drug delivery and tissue regeneration.
Adler-Abramovich, Lihi, Brahmachari, Sayanti, Bychenko, Darya, DeGrado, William F, Gazit, Ehud, Kolusheva, Sofiya, Mensa, Bruk, Schmidt, Nathan W, Schnaider, Lee, Shaham-Niv, Shira, Shimon, Linda JW   +10 more
core   +3 more sources

Novel antimicrobial activities of a peptide derived from a Japanese soybean fermented food, Natto, against Streptococcus pneumoniae and Bacillus subtilis group strains

AMB Express, 2017
We recently isolated a tumoricidal peptide from Natto, a Japanese traditional fermented food. In the present study, antimicrobial activity of the Natto peptide was examined. The peptide consisted of 45 amino acid residues, and its structure was predicted
Manabu Kitagawa, Tsukasa Shiraishi, Soh Yamamoto, Ryosuke Kutomi, Yasuo Ohkoshi, Toyotaka Sato, Hideki Wakui, Hideaki Itoh, Atsushi Miyamoto, Shin-ichi Yokota   +9 more
doaj   +1 more source

Cn-AMP2 from green coconut water is an anionic anticancer peptide [PDF]

, 2014
Globally, death due to cancers is likely to rise to over 20 million by 2030,which has created an urgent need for novel approaches to anticancer therapies such as the development of host defence peptides.
Al-Benna, Avner, Balderas-Renteria, Bray, Chan, Cho, Cho, Cragg, Cragg, Dawson, Dennison, Dennison, Dennison, Dennison, Gaspar, Gotay, Harris, Harris, Harris, Harris, Harris, Hess, Hogberg, Khazir, Li, Lumb, Malde, Mandal, Mandal, Martin Sabroso, Newman, Nicolas, Oh, Pasupuleti, Phoenix, Phoenix, Phoenix, Phoenix, Prabhu, Prabhu, Rajanbabu, Riedl, Saraswathy, Shekhar, Song, Tsuda, Unnati, Urruticoechea, Van der Spoel, Varadhachary, Wall, Wang, Wang, Whitmore, Whitmore, Whitmore, Yeung   +56 more
core   +1 more source

A Review of Structural Characteristics and Structure-Function Relationship of Two-Peptide (Class IIb) Bacteriocins [PDF]

Shipin Kexue, 2023
The two-peptide (class IIb) bacteriocins are generally thermostable small-molecule (< 10 kDa) two-component antimicrobial peptides produced by Gram-positive bacteria.
ZHAO Penghao, SHANG Jiacui, CHEN Yuhan, DUAN Bofan, MENG Xiangchen
doaj   +1 more source

In silico structural evaluation of short cationic antimicrobial peptides [PDF]

, 2018
© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).Cationic peptides with ...
Malkinson, John, Passarini, Ilaria, Rossiter, Sharon, Zloh, Mire   +3 more
core   +3 more sources

Targeted Antimicrobial Peptides [PDF]

Frontiers in Immunology, 2012
The existence of natural antimicrobial substances, contributing to the mechanisms of host defenses, has been recognized since the late nineteenth century. In 1963, the in vitro antibacterial activity of leukocyte extracts was attributed to basic proteins.
openaire   +3 more sources

Antisense PNA accumulates in Escherichia coli and mediates a long post-antibiotic effect [PDF]

, 2007
Antisense agents that target growth-essential genes display surprisingly potent bactericidal properties. In particular, peptide nucleic acid (PNA) and phosphorodiamidate morpholino oligomers linked to cationic carrier peptides are effective in time kill ...
Behmanesh, Mehrdad, Dryselius, Rikard, Faridani, Omid R, Ganyu, Anita, Goh, Shan, Good, Liam, Klok, Erik Jan, Nikravesh, Abbas, Sadeghizadeh, Majid, Zain, Rula   +9 more
core   +2 more sources

Design of a novel tryptophan-rich membrane-active antimicrobial peptide from the membrane-proximal region of the HIV glycoprotein, gp41

Beilstein Journal of Organic Chemistry, 2012
A number of physicochemical characteristics have been described which contribute to the biological activity of antimicrobial peptides. This information was used to design a novel antimicrobial peptide sequence by using an intrinsically inactive membrane ...
Evan F. Haney, Leonard T. Nguyen, David J. Schibli, Hans J. Vogel   +3 more
doaj   +1 more source

A novel antibacterial peptide derived from Crocodylus siamensis haemoglobin hydrolysate induces membrane permeabilization causing iron dysregulation, oxidative stress and bacterial death [PDF]

, 2017
Aims A novel antibacterial peptide from Crocodylus siamensis haemoglobin hydrolysate (CHH) was characterized for antimicrobial activity. Methods and Results CHHs were hydrolysed for 2 h (2 h-CHH), 4 h (4h-CHH), 6 h (6 h-CHH) and 8 h (8 h-CHH). The
Adje, Ali, Arroume, Arroume, Chitemerere, Daoud, Froidevaux, Gault, Jandaruang, Jangpromma, Kabbua, Maddocks, Maijaroen, Mbah, Michel, Miller, Osman, Pakdeesuwan, Pata, Phosri, Phosri, Sato, Schwyn, Solanky, Song, Srihongthong, Vasilchenko, Winkelmann, Yu, Zheng   +29 more
core   +2 more sources

Phosphonopeptides Revisited, in an Era of Increasing Antimicrobial Resistance [PDF]

, 2020
Given the increase in resistance to antibacterial agents, there is an urgent need for the development of new agents with novel modes of action. As an interim solution, it is also prudent to reinvestigate old or abandoned antibacterial compounds to assess
Anderson, Rosaleen, Bedernjak, Alexandre F., Cummings, Stephen P., Day, Kathryn M., Gray, Mark, Jones, Amanda L., Marrs, Emma C.L., Perry, John D., Varadi, Linda   +8 more
core   +2 more sources