Results 211 to 220 of about 410,913 (288)

Antimicrobial Resistance Profiles of Bacteria Isolated from the Animal Health Sector in Zambia (2020-2024): Opportunities to Strengthen Antimicrobial Resistance Surveillance and Stewardship Programs. [PDF]

Antibiotics (Basel)
Sinyawa T, Goma F, Chileshe C, Mudenda NB, Mudenda S, Siame A, Simwinji FM, Hadunka MA, Chibwe B, Kaunda K, Mainda G, Phiri BSJ, Kasanga M, Mufwambi W, Mukale S, Bambala A, Hangoma J, Mabuku N, Bowa B, Kabunda O, Nkamba M, Chazya R, Nakazwe R, Malambo M, Muhimba Z, Mubamba S, Champo M, Mukuma M, Dautu G, Lukwesa C, Shikanga OT, Masaninga F, Chibi M, Mwadetsa SD, Savory T, Chizimu JY, Muma JB, Maseka C, Chilengi R.   +38 more
europepmc   +1 more source

ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging

Advanced Science, EarlyView.
In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo, Shengjie Cui, Xi Wen, Yidi Wang, Ben Wu, Yixiang Wang, Yan Gu   +6 more
wiley   +1 more source

Identification of antimicrobial resistance genes in Escherichia coli through network diffusion. [PDF]

J Antimicrob Chemother
Mansouri A, Durazzi F, Ihsan MA, Griffin S, Manfreda G, Valdramidis VP, Pasquali F, Remondini D.   +7 more
europepmc   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

A Bayesian Semi-Mechanistic Framework for Modelling Antimicrobial Resistance

Srimokla O, Cavany S, Petrie J, Pritchard M, Nebykova A, Aguilar G, Dolecek C, Cooper B.   +7 more
europepmc   +1 more source

Advances in biosensor technologies for the detection of antimicrobial resistance in <i>Staphylococcus aureus</i>. [PDF]

Front Cell Infect Microbiol
Pérez-Rodríguez M, Serrano-Pertierra E, Blanco-López MC.   +2 more
europepmc   +1 more source

Structural and Functional Characterization of EXPO‐Derived Extracellular Vesicles in Plants

Advanced Science, EarlyView.
In this study, 3D electron tomography (ET), cryo‐ET, and immunogold transmission electron microscopy (TEM) are employed to characterize plant extracellular vesicles (EVs) under physiological conditions. EVs are classified into three distinct categories according to their size, content, and molecular‐marker profiles. Furthermore, Exo70E2‐positive medium
Jiayang Gao, Yanbin Li, Shengqi Zhang, Yilin He, Zhiqi Liu, Juan Wang, Jingmin Hua, Jinyu Chen, Junru Zhong, Huan Zhong, Yiji Xia, Yong Cui, Liwen Jiang   +12 more
wiley   +1 more source

SeqAfrica: empowering Africa's fight against antimicrobial resistance through genomics. [PDF]

Front Public Health
Nilsson P, Gibson CT, Thornval NR, Lacy-Roberts N, Odgaard C, Owusu-Nyantakyi C, Amuasi GR, Boateng W, Mohktar Q, Bortey A, Odih EE, Sunmonu GT, Kumburu HH, Sonda T, Bhiman JN, Amoako DG, du Plessis M, Adu B, van Zwetselaar M, von Gottberg A, Mmbaga BT, Okeke IN, Smith AM, Egyir B, Hendriksen RS.   +24 more
europepmc   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source