Deep Learning Enables Identification of Antimicrobial Peptides Through Mechanochromic Fingerprints
Angewandte Chemie, EarlyView.We demonstrate a new platform for antimicrobial peptide identification by combining polydiacetylene, hyperspectral imaging, and deep learning. The trained model classifies distinct spectral fingerprints into 14 peptide classes with 96.79% accuracy, revealing previously hidden molecular information beyond conventional colorimetric sensing.
Jiali Chen +4 more
wiley +2 more sources
The impact of faster antimicrobial susceptibility testing report and dual antimicrobial susceptibility testing cards on the antibiotic therapy and economics of hospitalized bloodstream infection patients. [PDF]
BMC MicrobiolYue J +9 more
europepmc +1 more source
Refining a preclinical model of viral myocarditis in accordance with biotech standards
Animal Models and Experimental Medicine, EarlyView.This study aimed to refine a murine model of Coxsackievirus B3‐induced myocarditis by integrating dietary and imaging innovations to improve animal welfare, data quality, and clinical applicability. The refined diet significantly reduced animal health burden, reduced weight loss, and stabilized blood glucose during development of cardiac inflammation ...
Jonas Stewen +9 more
wiley +1 more source
Evaluation of an automated reader for disc diffusion antimicrobial susceptibility testing in a routine microbiology laboratory. [PDF]
PLoS OneOrlandi Barth P +9 more
europepmc +1 more source
Natural Aging of Biomaterials in Ambient and Physiological Environments
Advanced NanoBiomed Research, EarlyView.Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley +1 more source
The impact of inoculation methods on bacterial aggregation and antimicrobial susceptibility testing. [PDF]
Microbiology (Reading)Cai YM, Wang ZZ, Webber MA, Malone JG.
europepmc +1 more source
Nanodiamonds as Bioactive Platforms to Modulate Microbial, Mammalian, and Vertebrate Systems
Advanced NanoBiomed Research, EarlyView.Nanodiamonds (NDs) are biocompatible and antibacterial nanomaterials that support mammalian cell growth while inhibiting bacterial pathogens. NDs showed strong antibacterial activity, with Escherichia coli being more sensitive than Staphylococcus aureus. At 10 mg/mL, both bacteria exhibited ~8% viability.
Aaqil Rifai +6 more
wiley +1 more source
Modified Titanium Dental Implants: The Current Progress of Soft‐Tissue Integration Methods
Advanced NanoBiomed Research, EarlyView.Dental implants are an established solution for tooth loss, yet achieving soft tissue integration (STI) around the transmucosal region remains a challenge. The natural tooth–gingiva interface is poorly replicated on titanium implants. This review explores surface modification strategies, ranging from surface chemistry and topography to biological ...
Daniel De Maria +5 more
wiley +1 more source
Poloxamer dilution as an on-demand alternative to agar dilution-based antimicrobial susceptibility testing. [PDF]
J Clin MicrobiolUy MTJ +4 more
europepmc +1 more source
Piezoelectric Nanocomposite Hydrogel for Wireless Neural Stimulation and Tissue Augmentation
Advanced NanoBiomed Research, EarlyView.A cell/tissue supporting piezoelectric hydrogel system (PZ‐gel) that incorporates ferroelectric, pyroelectric, and piezoelectric ceramic material barium titanate into an alginate/carboxymethyl chitosan hydrogel. The PZ‐gel can be sonoactivated for wireless neural cell and tissue stimulation, with the potential to be used as a stimulatory cell substrate
Mohammad Mohammadi +3 more
wiley +1 more source