Results 171 to 180 of about 25,615 (222)

Substituted Xanthones as Antimycobacterial Agents, Part 2: Antimycobacterial Activity

Archiv der Pharmazie, 1998
A series of substituted xanthones was tested for their activity against four mycobacterial strains (Mycobacterium tuberculosis, M. avium, M. lufu, M. smegmatis) by determination of the minimum inhibitory concentrations (MIC values). For the most active compounds, supplementary characterisation was performed by bacterial growth kinetics, which allows a ...
Pickert, Martina, Schaper, Klaus Jürgen, Frahm, August Wilhelm   +2 more
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Antimycobacterial thiobenzanilides

Collection of Czechoslovak Chemical Communications, 1990
A group of 30 thiobenzanilides active against Mycobacterium kansasii have been synthesized and their 1H NMR and UV spectra and RM values (TLC on silica gel impregnated with methylsilicone oil) have been measured. From the correlation between the chemical shifts of the thioamide proton in the 1H NMR spectra and the Hammett constants it can be concluded ...
Karel Waisser, Nestor Houngbedji, Miloš Macháček, Miroslav Sekera, Josef Urban, Želmíra Odlerová   +5 more
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Malabsorption of Antimycobacterial Medications

New England Journal of Medicine, 1993
To the Editor: Malabsorption of antimycobacterial drugs has been reported in one person with AIDS coinfected with Mycobacterium tuberculosis and 26 patients with AIDS coinfected with M.
C A, Peloquin, A A, MacPhee, S E, Berning   +2 more
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Quinones as antimycobacterial agents

Bioorganic & Medicinal Chemistry, 2004
Mycobacterium tuberculosis is a serious worldwide health threat, killing almost 3 million people per year. Other mycobacterial species, especially Mycobacterium avium, are emerging pathogens in the immunocompromised population, most notably AIDS patients. These nontuberculous mycobacteria (NTM) are ubiquitous in the environment, and naturally resistant
Thuyanh, Tran, Ekta, Saheba, Ariana V, Arcerio, Violeta, Chavez, Qing-Yi, Li, Luis E, Martinez, Todd P, Primm   +6 more
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Antimycobacterial activity of ‘Virkon’

Journal of Hospital Infection, 1993
The peroxygen-based disinfectant, 'Virkon' (at concentrations of 2, 3 and 4%) was tested against Mycobacterium tuberculosis and M. avium-intracellulare over exposure times ranging between 30 and 120 min. Two test procedures were used: (a) a standard plate method, (b) a method incorporating the use of the 'Bactec' 460 radiometric system to chart ...
S J, Broadley, J R, Furr, P A, Jenkins, A D, Russell   +3 more
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New Agents with Antimycobacterial Activity

Archiv der Pharmazie, 2005
AbstractIn this paper, we report that a series of structurally simple a‐halogenoacetamides (1–8) show potent and excellent antimycobacterial activities against drug‐sensitive Mycobacterium tuberculosis H37Rv and drug‐resistant M. avium.
José, Marco-Contelles, Elena, Gómez-Sánchez   +1 more
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Heterocyclic Isosters of Antimycobacterial Salicylanilides.

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Josef, Matyk, Karel, Waisser, Katerina, Drazková, Jirí, Kunes, Vera, Klimesová, Karel, Palát, Jarmila, Kaustová   +6 more
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Natural Antimycobacterial Metabolites: Current Status

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Adewole L, Okunade, Memory P F, Elvin-Lewis, Walter H, Lewis   +2 more
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Antimycobacterial Drugs

1998
Abstract Antimycobacterial agents embrace a wide array of drug classes and are used to treat a host of infections. These infections include tuberculosis, the disease caused by Mycobacterium tuberculosis (MTB); leprosy, the disease caused by M.
Charles A Peloquin, Michael D Iseman
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Antimycobacterial agents

2016
Compounds represented by the formula [1] ##STR1## R.sub.1 is H or a substituent; R.sub.2 and R.sub.3 are C.sub.1 -C.sub.3 alkyl; R.sub.4 is siderophore group e.g. CH.sub.3 --(CH.sub.2).sub.n --C(O)--N(OH)--(CH.sub.2).sub.m -- with n=10-22, m=2-6; X is O, S, or NH; X.sub.1 is O or NH; Y is H or alkyl; Z is H or substituted amino, e.g., t-BocNH or CbzNH,
Miller, Marvin J, Xu, Yanping
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